Difference between revisions of "Team:OUC-China"
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Revision as of 13:38, 2 September 2015
![](https://static.igem.org/mediawiki/2015/4/4b/OUC-China-Team_Logo.png)
Platform for Electronmagnetic Control
HOW DOES IT WORK?
This summer we are trying to design a platform for remote regular of gene expression by electromagnetic signal.
![](https://static.igem.org/mediawiki/2015/9/97/OUC-China-ThumbGallery_01.png)
STEP 1
The platform is mainly constructed by magnetic receiver and regulator.
![](https://static.igem.org/mediawiki/2015/a/aa/OUC-China-ThumbGallery_02.png)
STEP 2
Induced by electromagnetic fidle, magnetic receiver would be heated.
![](https://static.igem.org/mediawiki/2015/3/39/OUC-China-ThumbGallery_03.png)
STEP 3
In response to change in temprature, thermosensitive regulator would activate GFP expression.
Magnetic Receiver
For magnetic receiver, we choose ferritin, the iron-storage protein in organisms, which could synthesis terric***core in its hollow protein shell. When exposed to electromagnetic field, the ferritin oxihydroxide core would be heated.
More details![](https://static.igem.org/mediawiki/2015/1/19/OUC-China-ThumbGallery_04.png)
![](https://static.igem.org/mediawiki/2015/9/93/OUC-China-ThumbGallery_05.png)
Thermosensitive Regulator
For thermosensitive regulator, we choose RNA thermosensitive and constructed a thermosensitive T7 RNA polymerase. RNA thermometer is a structured RNA which could expose RBS only when heated. The thermosensitive T7 RNA polymerase is a normal T7 RNA polymerase at the selected locus of which was inserted by a temprature-sensitive intein, which could self-splice at specific temperature.
More details