Difference between revisions of "Team:Warwick"

 
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        <div class = "title">Under Construction.</div>
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        <p>Warwick iGEM</p>
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        <a href="https://twitter.com/WarwickIgem15" class="twitter-follow-button" data-show-count="true" data-size="large">Follow @WarwickIgem15</a>
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<h4> Our Project </h4>
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<p>Our team's aim is to create a tool box allowing the selective allocation of specific cell types to an engineered DNA scaffold, using zinc finger binding proteins on an E. coli model. Our research would allow for the self assembly of complex multi-type cell structures. The project will advance in progressive bands of complexity: designing and cloning the zinc finger coated E. coli cells, constructing DNA structure to allow for the cells to bind, further development of the zinc finger binding proteins allowing for multiple cell types to coexist on the DNA structure, and finally designing complex 3-D structures that the cells will be able to self assemble into. This has possible applications throughout medicine. Our research would contribute potentially to 3-D printing organic tissues, allowing for customised living tissues to be engineered.
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At Warwick iGEM we are passionate about the art of science, the way we can meld biology with design to make a product greater than the sum of its parts. We were inspired by this paper (http://www.nature.com/nmeth/journal/v10/n5/full/nmeth.2407.html) on using zinc fingers to barcode cells with fluorescently tagged double stranded DNA oligos; and considered whether it was possible to use these same zinc finger proteins in a way that has never been done before. By modifying our cells to express zinc finger binding domains on the outside of the cell wall could we, in the same manner that the DNA is bound to the cells in the paper, instead bind the cells to fixed structured DNA on a 2D plane? And then, using existing DNA origami research, could we expand this into creating self assembling 3D cell structures? It’s an improbable feat with an impossible goal, yet we shall strive all the more to reach it.
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Fluorescent microscopy has long been the go to method for validating protein expression, and we are carrying on this long tradition by tying the expression of cell surface zinc fingers with the expression of fluorescent proteins inside the cell. By using multiple different zinc fingers with unique specific binding sites we allow different cell types to bond simultaneously to our DNA structure. The potential applications of this are limitless, imagine layers of different types of synthetic tissues; the construction of lab made skin and other organs. Imagine also a world where advanced materials with enhanced properties made cheaply by multiple different cells working together is possible.
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As a proof of concept, that it is possible to bind different cell types to the same structure we are engineering E. coli to express different coloured fluorescent proteins along with their unique zinc finger proteins, showing visually how many different coloured cells can coexist in a controlled environment. Coincidentally, this allows us also to create art by arranging groups of coloured cells into images, allowing for some of the first fully coloured images made using only living cells.
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margin-left: 0;
 +
}
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 +
width: 75%;
 +
clear: none;
 +
margin-left: 0;
 +
}
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 +
width: 66.6666666667%;
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clear: none;
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margin-left: 0;
 +
}
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 +
width: 58.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
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.\36 u\28wide\29, .\36 u\24\28wide\29 {
 +
width: 50%;
 +
clear: none;
 +
margin-left: 0;
 +
}
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.\35 u\28wide\29, .\35 u\24\28wide\29 {
 +
width: 41.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
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.\34 u\28wide\29, .\34 u\24\28wide\29 {
 +
width: 33.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\33 u\28wide\29, .\33 u\24\28wide\29 {
 +
width: 25%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
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.\32 u\28wide\29, .\32 u\24\28wide\29 {
 +
width: 16.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 u\28wide\29, .\31 u\24\28wide\29 {
 +
width: 8.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 2u\24\28wide\29 + *,
 +
.\31 1u\24\28wide\29 + *,
 +
.\31 0u\24\28wide\29 + *,
 +
.\39 u\24\28wide\29 + *,
 +
.\38 u\24\28wide\29 + *,
 +
.\37 u\24\28wide\29 + *,
 +
.\36 u\24\28wide\29 + *,
 +
.\35 u\24\28wide\29 + *,
 +
.\34 u\24\28wide\29 + *,
 +
.\33 u\24\28wide\29 + *,
 +
.\32 u\24\28wide\29 + *,
 +
.\31 u\24\28wide\29 + * {
 +
clear: left;
 +
}
 +
 +
.\-11u\28wide\29 {
 +
margin-left: 91.66667%;
 +
}
 +
 +
.\-10u\28wide\29 {
 +
margin-left: 83.33333%;
 +
}
 +
 +
.\-9u\28wide\29 {
 +
margin-left: 75%;
 +
}
 +
 +
.\-8u\28wide\29 {
 +
margin-left: 66.66667%;
 +
}
 +
 +
.\-7u\28wide\29 {
 +
margin-left: 58.33333%;
 +
}
 +
 +
.\-6u\28wide\29 {
 +
margin-left: 50%;
 +
}
 +
 +
.\-5u\28wide\29 {
 +
margin-left: 41.66667%;
 +
}
 +
 +
.\-4u\28wide\29 {
 +
margin-left: 33.33333%;
 +
}
 +
 +
.\-3u\28wide\29 {
 +
margin-left: 25%;
 +
}
 +
 +
.\-2u\28wide\29 {
 +
margin-left: 16.66667%;
 +
}
 +
 +
.\-1u\28wide\29 {
 +
margin-left: 8.33333%;
 +
}
 +
 +
}
 +
 +
@media screen and (max-width: 1080px) {
 +
 +
.row > * {
 +
padding: 40px 0 0 40px;
 +
}
 +
 +
.row {
 +
margin: -40px 0 -1px -40px;
 +
}
 +
 +
.row.uniform > * {
 +
padding: 40px 0 0 40px;
 +
}
 +
 +
.row.uniform {
 +
margin: -40px 0 -1px -40px;
 +
}
 +
 +
.row.\32 00\25 > * {
 +
padding: 80px 0 0 80px;
 +
}
 +
 +
.row.\32 00\25 {
 +
margin: -80px 0 -1px -80px;
 +
}
 +
 +
.row.uniform.\32 00\25 > * {
 +
padding: 80px 0 0 80px;
 +
}
 +
 +
.row.uniform.\32 00\25 {
 +
margin: -80px 0 -1px -80px;
 +
}
 +
 +
.row.\31 50\25 > * {
 +
padding: 60px 0 0 60px;
 +
}
 +
 +
.row.\31 50\25 {
 +
margin: -60px 0 -1px -60px;
 +
}
 +
 +
.row.uniform.\31 50\25 > * {
 +
padding: 60px 0 0 60px;
 +
}
 +
 +
.row.uniform.\31 50\25 {
 +
margin: -60px 0 -1px -60px;
 +
}
 +
 +
.row.\35 0\25 > * {
 +
padding: 20px 0 0 20px;
 +
}
 +
 +
.row.\35 0\25 {
 +
margin: -20px 0 -1px -20px;
 +
}
 +
 +
.row.uniform.\35 0\25 > * {
 +
padding: 20px 0 0 20px;
 +
}
 +
 +
.row.uniform.\35 0\25 {
 +
margin: -20px 0 -1px -20px;
 +
}
 +
 +
.row.\32 5\25 > * {
 +
padding: 10px 0 0 10px;
 +
}
 +
 +
.row.\32 5\25 {
 +
margin: -10px 0 -1px -10px;
 +
}
 +
 +
.row.uniform.\32 5\25 > * {
 +
padding: 10px 0 0 10px;
 +
}
 +
 +
.row.uniform.\32 5\25 {
 +
margin: -10px 0 -1px -10px;
 +
}
 +
 +
.\31 2u\28normal\29, .\31 2u\24\28normal\29 {
 +
width: 100%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 1u\28normal\29, .\31 1u\24\28normal\29 {
 +
width: 91.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 0u\28normal\29, .\31 0u\24\28normal\29 {
 +
width: 83.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\39 u\28normal\29, .\39 u\24\28normal\29 {
 +
width: 75%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\38 u\28normal\29, .\38 u\24\28normal\29 {
 +
width: 66.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\37 u\28normal\29, .\37 u\24\28normal\29 {
 +
width: 58.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\36 u\28normal\29, .\36 u\24\28normal\29 {
 +
width: 50%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\35 u\28normal\29, .\35 u\24\28normal\29 {
 +
width: 41.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\34 u\28normal\29, .\34 u\24\28normal\29 {
 +
width: 33.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\33 u\28normal\29, .\33 u\24\28normal\29 {
 +
width: 25%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\32 u\28normal\29, .\32 u\24\28normal\29 {
 +
width: 16.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 u\28normal\29, .\31 u\24\28normal\29 {
 +
width: 8.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 2u\24\28normal\29 + *,
 +
.\31 1u\24\28normal\29 + *,
 +
.\31 0u\24\28normal\29 + *,
 +
.\39 u\24\28normal\29 + *,
 +
.\38 u\24\28normal\29 + *,
 +
.\37 u\24\28normal\29 + *,
 +
.\36 u\24\28normal\29 + *,
 +
.\35 u\24\28normal\29 + *,
 +
.\34 u\24\28normal\29 + *,
 +
.\33 u\24\28normal\29 + *,
 +
.\32 u\24\28normal\29 + *,
 +
.\31 u\24\28normal\29 + * {
 +
clear: left;
 +
}
 +
 +
.\-11u\28normal\29 {
 +
margin-left: 91.66667%;
 +
}
 +
 +
.\-10u\28normal\29 {
 +
margin-left: 83.33333%;
 +
}
 +
 +
.\-9u\28normal\29 {
 +
margin-left: 75%;
 +
}
 +
 +
.\-8u\28normal\29 {
 +
margin-left: 66.66667%;
 +
}
 +
 +
.\-7u\28normal\29 {
 +
margin-left: 58.33333%;
 +
}
 +
 +
.\-6u\28normal\29 {
 +
margin-left: 50%;
 +
}
 +
 +
.\-5u\28normal\29 {
 +
margin-left: 41.66667%;
 +
}
 +
 +
.\-4u\28normal\29 {
 +
margin-left: 33.33333%;
 +
}
 +
 +
.\-3u\28normal\29 {
 +
margin-left: 25%;
 +
}
 +
 +
.\-2u\28normal\29 {
 +
margin-left: 16.66667%;
 +
}
 +
 +
.\-1u\28normal\29 {
 +
margin-left: 8.33333%;
 +
}
 +
 +
}
 +
 +
@media screen and (max-width: 840px) {
 +
 +
.row > * {
 +
padding: 30px 0 0 30px;
 +
}
 +
 +
.row {
 +
margin: -30px 0 -1px -30px;
 +
}
 +
 +
.row.uniform > * {
 +
padding: 30px 0 0 30px;
 +
}
 +
 +
.row.uniform {
 +
margin: -30px 0 -1px -30px;
 +
}
 +
 +
.row.\32 00\25 > * {
 +
padding: 60px 0 0 60px;
 +
}
 +
 +
.row.\32 00\25 {
 +
margin: -60px 0 -1px -60px;
 +
}
 +
 +
.row.uniform.\32 00\25 > * {
 +
padding: 60px 0 0 60px;
 +
}
 +
 +
.row.uniform.\32 00\25 {
 +
margin: -60px 0 -1px -60px;
 +
}
 +
 +
.row.\31 50\25 > * {
 +
padding: 45px 0 0 45px;
 +
}
 +
 +
.row.\31 50\25 {
 +
margin: -45px 0 -1px -45px;
 +
}
 +
 +
.row.uniform.\31 50\25 > * {
 +
padding: 45px 0 0 45px;
 +
}
 +
 +
.row.uniform.\31 50\25 {
 +
margin: -45px 0 -1px -45px;
 +
}
 +
 +
.row.\35 0\25 > * {
 +
padding: 15px 0 0 15px;
 +
}
 +
 +
.row.\35 0\25 {
 +
margin: -15px 0 -1px -15px;
 +
}
 +
 +
.row.uniform.\35 0\25 > * {
 +
padding: 15px 0 0 15px;
 +
}
 +
 +
.row.uniform.\35 0\25 {
 +
margin: -15px 0 -1px -15px;
 +
}
 +
 +
.row.\32 5\25 > * {
 +
padding: 7.5px 0 0 7.5px;
 +
}
 +
 +
.row.\32 5\25 {
 +
margin: -7.5px 0 -1px -7.5px;
 +
}
 +
 +
.row.uniform.\32 5\25 > * {
 +
padding: 7.5px 0 0 7.5px;
 +
}
 +
 +
.row.uniform.\32 5\25 {
 +
margin: -7.5px 0 -1px -7.5px;
 +
}
 +
 +
.\31 2u\28narrow\29, .\31 2u\24\28narrow\29 {
 +
width: 100%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 1u\28narrow\29, .\31 1u\24\28narrow\29 {
 +
width: 91.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 0u\28narrow\29, .\31 0u\24\28narrow\29 {
 +
width: 83.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\39 u\28narrow\29, .\39 u\24\28narrow\29 {
 +
width: 75%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\38 u\28narrow\29, .\38 u\24\28narrow\29 {
 +
width: 66.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\37 u\28narrow\29, .\37 u\24\28narrow\29 {
 +
width: 58.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\36 u\28narrow\29, .\36 u\24\28narrow\29 {
 +
width: 50%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\35 u\28narrow\29, .\35 u\24\28narrow\29 {
 +
width: 41.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\34 u\28narrow\29, .\34 u\24\28narrow\29 {
 +
width: 33.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\33 u\28narrow\29, .\33 u\24\28narrow\29 {
 +
width: 25%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\32 u\28narrow\29, .\32 u\24\28narrow\29 {
 +
width: 16.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 u\28narrow\29, .\31 u\24\28narrow\29 {
 +
width: 8.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 2u\24\28narrow\29 + *,
 +
.\31 1u\24\28narrow\29 + *,
 +
.\31 0u\24\28narrow\29 + *,
 +
.\39 u\24\28narrow\29 + *,
 +
.\38 u\24\28narrow\29 + *,
 +
.\37 u\24\28narrow\29 + *,
 +
.\36 u\24\28narrow\29 + *,
 +
.\35 u\24\28narrow\29 + *,
 +
.\34 u\24\28narrow\29 + *,
 +
.\33 u\24\28narrow\29 + *,
 +
.\32 u\24\28narrow\29 + *,
 +
.\31 u\24\28narrow\29 + * {
 +
clear: left;
 +
}
 +
 +
.\-11u\28narrow\29 {
 +
margin-left: 91.66667%;
 +
}
 +
 +
.\-10u\28narrow\29 {
 +
margin-left: 83.33333%;
 +
}
 +
 +
.\-9u\28narrow\29 {
 +
margin-left: 75%;
 +
}
 +
 +
.\-8u\28narrow\29 {
 +
margin-left: 66.66667%;
 +
}
 +
 +
.\-7u\28narrow\29 {
 +
margin-left: 58.33333%;
 +
}
 +
 +
.\-6u\28narrow\29 {
 +
margin-left: 50%;
 +
}
 +
 +
.\-5u\28narrow\29 {
 +
margin-left: 41.66667%;
 +
}
 +
 +
.\-4u\28narrow\29 {
 +
margin-left: 33.33333%;
 +
}
 +
 +
.\-3u\28narrow\29 {
 +
margin-left: 25%;
 +
}
 +
 +
.\-2u\28narrow\29 {
 +
margin-left: 16.66667%;
 +
}
 +
 +
.\-1u\28narrow\29 {
 +
margin-left: 8.33333%;
 +
}
 +
 +
}
 +
 +
@media screen and (max-width: 736px) {
 +
 +
.row > * {
 +
padding: 20px 0 0 20px;
 +
}
 +
 +
.row {
 +
margin: -20px 0 -1px -20px;
 +
}
 +
 +
.row.uniform > * {
 +
padding: 20px 0 0 20px;
 +
}
 +
 +
.row.uniform {
 +
margin: -20px 0 -1px -20px;
 +
}
 +
 +
.row.\32 00\25 > * {
 +
padding: 40px 0 0 40px;
 +
}
 +
 +
.row.\32 00\25 {
 +
margin: -40px 0 -1px -40px;
 +
}
 +
 +
.row.uniform.\32 00\25 > * {
 +
padding: 40px 0 0 40px;
 +
}
 +
 +
.row.uniform.\32 00\25 {
 +
margin: -40px 0 -1px -40px;
 +
}
 +
 +
.row.\31 50\25 > * {
 +
padding: 30px 0 0 30px;
 +
}
 +
 +
.row.\31 50\25 {
 +
margin: -30px 0 -1px -30px;
 +
}
 +
 +
.row.uniform.\31 50\25 > * {
 +
padding: 30px 0 0 30px;
 +
}
 +
 +
.row.uniform.\31 50\25 {
 +
margin: -30px 0 -1px -30px;
 +
}
 +
 +
.row.\35 0\25 > * {
 +
padding: 10px 0 0 10px;
 +
}
 +
 +
.row.\35 0\25 {
 +
margin: -10px 0 -1px -10px;
 +
}
 +
 +
.row.uniform.\35 0\25 > * {
 +
padding: 10px 0 0 10px;
 +
}
 +
 +
.row.uniform.\35 0\25 {
 +
margin: -10px 0 -1px -10px;
 +
}
 +
 +
.row.\32 5\25 > * {
 +
padding: 5px 0 0 5px;
 +
}
 +
 +
.row.\32 5\25 {
 +
margin: -5px 0 -1px -5px;
 +
}
 +
 +
.row.uniform.\32 5\25 > * {
 +
padding: 5px 0 0 5px;
 +
}
 +
 +
.row.uniform.\32 5\25 {
 +
margin: -5px 0 -1px -5px;
 +
}
 +
 +
.\31 2u\28mobile\29, .\31 2u\24\28mobile\29 {
 +
width: 100%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 1u\28mobile\29, .\31 1u\24\28mobile\29 {
 +
width: 91.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 0u\28mobile\29, .\31 0u\24\28mobile\29 {
 +
width: 83.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\39 u\28mobile\29, .\39 u\24\28mobile\29 {
 +
width: 75%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\38 u\28mobile\29, .\38 u\24\28mobile\29 {
 +
width: 66.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\37 u\28mobile\29, .\37 u\24\28mobile\29 {
 +
width: 58.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\36 u\28mobile\29, .\36 u\24\28mobile\29 {
 +
width: 50%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\35 u\28mobile\29, .\35 u\24\28mobile\29 {
 +
width: 41.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\34 u\28mobile\29, .\34 u\24\28mobile\29 {
 +
width: 33.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\33 u\28mobile\29, .\33 u\24\28mobile\29 {
 +
width: 25%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\32 u\28mobile\29, .\32 u\24\28mobile\29 {
 +
width: 16.6666666667%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 u\28mobile\29, .\31 u\24\28mobile\29 {
 +
width: 8.3333333333%;
 +
clear: none;
 +
margin-left: 0;
 +
}
 +
 +
.\31 2u\24\28mobile\29 + *,
 +
.\31 1u\24\28mobile\29 + *,
 +
.\31 0u\24\28mobile\29 + *,
 +
.\39 u\24\28mobile\29 + *,
 +
.\38 u\24\28mobile\29 + *,
 +
.\37 u\24\28mobile\29 + *,
 +
.\36 u\24\28mobile\29 + *,
 +
.\35 u\24\28mobile\29 + *,
 +
.\34 u\24\28mobile\29 + *,
 +
.\33 u\24\28mobile\29 + *,
 +
.\32 u\24\28mobile\29 + *,
 +
.\31 u\24\28mobile\29 + * {
 +
clear: left;
 +
}
 +
 +
.\-11u\28mobile\29 {
 +
margin-left: 91.66667%;
 +
}
 +
 +
.\-10u\28mobile\29 {
 +
margin-left: 83.33333%;
 +
}
 +
 +
.\-9u\28mobile\29 {
 +
margin-left: 75%;
 +
}
 +
 +
.\-8u\28mobile\29 {
 +
margin-left: 66.66667%;
 +
}
 +
 +
.\-7u\28mobile\29 {
 +
margin-left: 58.33333%;
 +
}
 +
 +
.\-6u\28mobile\29 {
 +
margin-left: 50%;
 +
}
 +
 +
.\-5u\28mobile\29 {
 +
margin-left: 41.66667%;
 +
}
 +
 +
.\-4u\28mobile\29 {
 +
margin-left: 33.33333%;
 +
}
 +
 +
.\-3u\28mobile\29 {
 +
margin-left: 25%;
 +
}
 +
 +
.\-2u\28mobile\29 {
 +
margin-left: 16.66667%;
 +
}
 +
 +
.\-1u\28mobile\29 {
 +
margin-left: 8.33333%;
 +
}
 +
 +
}
 +
 +
/* Basic */
 +
 +
 +
body.is-scroll {
 +
background-attachment: scroll, scroll;
 +
background-size: auto, 100% auto;
 +
}
 +
 +
 +
 +
h1, h2, h3, h4, h5, h6 {
 +
 +
text-transform: uppercase;
 +
 +
}
 +
 +
h1 a, h2 a, h3 a, h4 a, h5 a, h6 a {
 +
color: inherit;
 +
text-decoration: none;
 +
}
 +
 +
h2 {
 +
font-size: 1.25em;
 +
letter-spacing: 8px;
 +
}
 +
 +
h3 {
 +
font-size: 1em;
 +
letter-spacing: 5px;
 +
}
 +
 +
strong, b {
 +
 +
}
 +
 +
em, i {
 +
font-style: italic;
 +
}
 +
 +
 +
 +
 +
 +
 +
 +
/* Image */
 +
 +
.image {
 +
display: inline-block;
 +
border: 0;
 +
}
 +
 +
.image img {
 +
display: block;
 +
width: 100%;
 +
}
 +
 +
.image.featured {
 +
display: block;
 +
width: 100%;
 +
margin: 0 0 2em 0;
 +
}
 +
 +
.image.fit {
 +
display: block;
 +
width: 100%;
 +
}
 +
 +
.image.left {
 +
float: left;
 +
margin: 0 2em 2em 0;
 +
}
 +
 +
.image.centered {
 +
display: block;
 +
margin: 0 0 2em 0;
 +
}
 +
 +
.image.centered img {
 +
margin: 0 auto;
 +
width: auto;
 +
}
 +
 +
 +
/* Form */
 +
 +
form label {
 +
display: block;
 +
margin: 0 0 0.5em 0;
 +
}
 +
 +
form input[type="text"],
 +
form input[type="email"],
 +
form input[type="password"],
 +
form select,
 +
form textarea {
 +
-moz-transition: background-color 0.35s ease-in-out;
 +
-webkit-transition: background-color 0.35s ease-in-out;
 +
-ms-transition: background-color 0.35s ease-in-out;
 +
transition: background-color 0.35s ease-in-out;
 +
-webkit-appearance: none;
 +
display: block;
 +
border: 0;
 +
background: #f1f1f1;
 +
width: 100%;
 +
padding: 0.75em;
 +
}
 +
 +
form input[type="text"]:focus,
 +
form input[type="email"]:focus,
 +
form input[type="password"]:focus,
 +
form select:focus,
 +
form textarea:focus {
 +
background: #f8f8f8;
 +
}
 +
 +
form input[type="text"],
 +
form input[type="email"],
 +
form input[type="password"],
 +
form select {
 +
line-height: 1em;
 +
}
 +
 +
form textarea {
 +
min-height: 12em;
 +
}
 +
 +
form .formerize-placeholder {
 +
color: #5a5959 !important;
 +
}
 +
 +
form ::-webkit-input-placeholder {
 +
color: #5a5959 !important;
 +
}
 +
 +
form :-moz-placeholder {
 +
color: #5a5959 !important;
 +
}
 +
 +
form ::-moz-placeholder {
 +
color: #5a5959 !important;
 +
}
 +
 +
form :-ms-input-placeholder {
 +
color: #5a5959 !important;
 +
}
 +
 +
form ::-moz-focus-inner {
 +
border: 0;
 +
}
 +
 +
form ul.actions {
 +
margin-bottom: 0;
 +
text-align: center;
 +
}
 +
 +
 +
 +
/* Button */
 +
 +
input[type="button"],
 +
input[type="submit"],
 +
input[type="reset"],
 +
button,
 +
.button {
 +
-moz-transition: background-color 0.35s ease-in-out, color 0.35s ease-in-out;
 +
-webkit-transition: background-color 0.35s ease-in-out, color 0.35s ease-in-out;
 +
-ms-transition: background-color 0.35s ease-in-out, color 0.35s ease-in-out;
 +
transition: background-color 0.35s ease-in-out, color 0.35s ease-in-out;
 +
-webkit-appearance: none;
 +
position: relative;
 +
display: inline-block;
 +
border: 0;
 +
background: #35b88f;
 +
color: #fff;
 +
text-shadow: 0 0 0.5px rgba(255, 255, 255, 0.25);
 +
cursor: pointer;
 +
text-decoration: none;
 +
outline: 0;
 +
padding: 1em 3em 1em 3em;
 +
text-align: center;
 +
border-radius: 3em;
 +
 +
}
 +
 +
input[type="button"]:hover,
 +
input[type="submit"]:hover,
 +
input[type="reset"]:hover,
 +
button:hover,
 +
.button:hover {
 +
background: #45c89f;
 +
}
 +
 +
input[type="button"].style2,
 +
input[type="submit"].style2,
 +
input[type="reset"].style2,
 +
button.style2,
 +
.button.style2 {
 +
color: #3a3939;
 +
background: #fff;
 +
box-shadow: inset 0 0 0 1px #fff;
 +
}
 +
 +
input[type="button"].style2:hover,
 +
input[type="submit"].style2:hover,
 +
input[type="reset"].style2:hover,
 +
button.style2:hover,
 +
.button.style2:hover {
 +
background: rgba(255, 255, 255, 0.1);
 +
color: #fff !important;
 +
text-shadow: 0 0 0.5px rgba(255, 255, 255, 0.25) !important;
 +
}
 +
 +
input[type="button"].style3,
 +
input[type="submit"].style3,
 +
input[type="reset"].style3,
 +
button.style3,
 +
.button.style3 {
 +
background: none;
 +
color: #3a3939;
 +
box-shadow: inset 0 0 0 1px #dad9d9;
 +
}
 +
 +
input[type="button"].style3:hover,
 +
input[type="submit"].style3:hover,
 +
input[type="reset"].style3:hover,
 +
button.style3:hover,
 +
.button.style3:hover {
 +
background: rgba(58, 57, 57, 0.025);
 +
}
 +
 +
/* Box */
 +
 +
.box {
 +
position: relative;
 +
margin-top: 9em;
 +
margin-bottom: 0;
 +
}
 +
 +
.box:after {
 +
content: '';
 +
display: block;
 +
position: absolute;
 +
top: -9em;
 +
left: 50%;
 +
height: 9em;
 +
border-left: solid 1px #fff;
 +
}
 +
 +
.box:before {
 +
content: '';
 +
display: block;
 +
width: 90px;
 +
height: 66px;
 +
position: absolute;
 +
left: 50%;
 +
top: -4.5em;
 +
margin-left: -45px;
 +
margin-top: -33px;
 +
background: url("images/arrow.svg") no-repeat;
 +
}
 +
 +
.box :last-child {
 +
margin-bottom: 0;
 +
}
 +
 +
.box.style1 {
 +
background: #fff;
 +
padding: 3em;
 +
}
 +
 +
.box.style1 .image {
 +
display: block;
 +
position: absolute;
 +
top: 0;
 +
width: 50%;
 +
height: 100%;
 +
background: #152E33;
 +
overflow: hidden;
 +
}
 +
 +
.box.style1 .image img {
 +
position: absolute;
 +
top: 0;
 +
height: 100%;
 +
width: auto;
 +
}
 +
 +
.box.style1 .inner > :last-child {
 +
margin: 0;
 +
}
 +
 +
.box.style1.right .image {
 +
left: 0;
 +
}
 +
 +
.box.style1.right .image img {
 +
right: 0;
 +
}
 +
 +
.box.style1.right .inner {
 +
margin-left: 50%;
 +
padding-left: 3em;
 +
}
 +
 +
.box.style1.left .image {
 +
right: 0;
 +
}
 +
 +
.box.style1.left .image img {
 +
left: 0;
 +
}
 +
 +
.box.style1.left .inner {
 +
margin-right: 50%;
 +
padding-right: 3em;
 +
}
 +
 +
.box.style2 {
 +
text-align: center;
 +
}
 +
 +
.box.style2 header {
 +
display: inline-block;
 +
background: #fff;
 +
padding: 2em 3em 2em 3em;
 +
margin: 0;
 +
}
 +
 +
.box.style2 header p {
 +
padding: 0;
 +
}
 +
 +
.box.style2 .inner {
 +
position: relative;
 +
padding: 40px 0 0px 0;
 +
}
 +
 +
.box.style2 .inner:after {
 +
content: '';
 +
display: block;
 +
position: absolute;
 +
top: 0;
 +
left: 50%;
 +
height: 100%;
 +
border-left: solid 1px #fff;
 +
}
 +
 +
.box.style2 .inner .row {
 +
position: relative;
 +
}
 +
 +
.box.style2 .inner .row:before {
 +
content: '';
 +
display: block;
 +
position: absolute;
 +
top: 50%;
 +
left: 20px;
 +
width: calc(100% - 40px);
 +
border-bottom: solid 1px #fff;
 +
}
 +
 +
.box.style2 .inner .image {
 +
position: relative;
 +
z-index: 1;
 +
padding: 20px;
 +
}
 +
 +
.box.style3 {
 +
background: #fff;
 +
padding: 3em;
 +
}
 +
 +
.box.style3 header {
 +
text-align: center;
 +
}
 +
 +
 +
/* Header */
 +
 +
#header {
 +
position: relative;
 +
color: #fff;
 +
text-shadow: 0 0 0.5px rgba(255, 255, 255, 0.25);
 +
text-align: center;
 +
margin: 0;
 +
padding: 14em 0 14em 0;
 +
cursor: default;
 +
}
 +
 +
#header header {
 +
display: inline-block;
 +
padding: 0 0 4.5em 0;
 +
}
 +
 +
#header header h1 {
 +
font-size: 2em;
 +
letter-spacing: 10px;
 +
}
 +
 +
#header header p {
 +
border-top: solid 1px rgba(255, 255, 255, 0.5);
 +
color: rgba(255, 255, 255, 0.75);
 +
text-shadow: 0 0 0.5px rgba(255, 255, 255, 0.1875);
 +
font-size: 1em;
 +
text-transform: uppercase;
 +
letter-spacing: 3px;
 +
padding: 0;
 +
margin-top: 0.35em;
 +
}
 +
 +
 +
 +
 +
 +
 +
 +
/* Banner */
 +
 +
#banner {
 +
position: relative;
 +
color: #fff;
 +
text-shadow: 0 0 0.5px rgba(255, 255, 255, 0.25);
 +
text-align: center;
 +
background: #35b88f url("images/banner.svg") bottom center no-repeat;
 +
padding: 5em 0 5em 0;
 +
margin: 0;
 +
background-size: 125% auto;
 +
}
 +
 +
#banner .button {
 +
color: #35b882;
 +
text-shadow: 0 0 0.5px rgba(53, 184, 130, 0.25);
 +
}
 +
 +
#banner header {
 +
margin: 0 0 2em 0;
 +
}
 +
 +
#banner header h2 {
 +
font-size: 1.75em;
 +
letter-spacing: 8px;
 +
}
 +
 +
#banner p {
 +
margin: 0;
 +
}
 +
 +
#banner footer {
 +
margin: 2em 0 0 0;
 +
}
 +
 +
#banner a {
 +
color: inherit;
 +
border-bottom-color: rgba(255, 255, 255, 0.5);
 +
}
 +
 +
#banner a:hover {
 +
border-bottom-color: rgba(255, 255, 255, 0);
 +
}
 +
 +
 +
 +
 +
 +
 +
 +
/* Narrow */
 +
 +
@media screen and (max-width: 840px) {
 +
 +
/* Basic */
 +
 +
body {
 +
background-color: #203936;
 +
background-size: auto, 100% auto;
 +
background-position: top left, top center;
 +
background-attachment: scroll, scroll;
 +
}
 +
 +
input, textarea, select {
 +
font-size: 14pt;
 +
}
 +
 +
h1, h2, h3, h4, h5, h6 {
 +
line-height: 1.5em;
 +
}
 +
 +
 +
/* Box */
 +
 +
.box {
 +
position: relative;
 +
}
 +
 +
.box section {
 +
margin: 0 0 2em 0;
 +
}
 +
 +
.box.style1 {
 +
padding: 2.5em 2em 2.5em 2em;
 +
}
 +
 +
.box.style1.right .inner {
 +
padding-left: 2em;
 +
}
 +
 +
.box.style1.left .inner {
 +
padding-right: 2em;
 +
}
 +
 +
.box.style2 header {
 +
padding: 2em;
 +
}
 +
 +
.box.style2 .inner {
 +
position: relative;
 +
padding: 30px 0 0 0;
 +
}
 +
 +
.box.style3 {
 +
padding: 2.5em 2em 2.5em 2em;
 +
}
 +
 +
/* Banner */
 +
 +
#banner {
 +
padding: 3.5em;
 +
background-size: 200% auto;
 +
}
 +
 +
#banner br {
 +
display: none;
 +
}
 +
 +
}
 +
 +
/* Mobile */
 +
 +
@media screen and (max-width: 736px) {
 +
 +
/* Basic */
 +
 +
* {
 +
text-shadow: none !important;
 +
}
 +
 +
body, input, textarea, select {
 +
line-height: 1.5em;
 +
font-size: 12pt;
 +
letter-spacing: 0;
 +
}
 +
 +
h2, h3, h4, h5, h6 {
 +
font-size: 1em;
 +
}
 +
 +
h2 {
 +
font-size: 1.25em;
 +
letter-spacing: 4px;
 +
}
 +
 +
 +
/* Button */
 +
 +
input[type="button"],
 +
input[type="submit"],
 +
input[type="reset"],
 +
button,
 +
.button {
 +
padding: 0.75em 0 0.75em 0;
 +
width: 100%;
 +
max-width: 320px;
 +
}
 +
 +
/* Box */
 +
 +
.box {
 +
margin-top: 4.5em;
 +
}
 +
 +
.box:after {
 +
top: -4.5em;
 +
height: 4.5em;
 +
}
 +
 +
.box:before {
 +
width: 45px;
 +
height: 33px;
 +
top: -2.25em;
 +
margin-left: -22.5px;
 +
margin-top: -16.5px;
 +
background-size: 45px 33px;
 +
}
 +
 +
.box.style1 {
 +
padding: 0;
 +
text-align: center;
 +
}
 +
 +
.box.style1 .image {
 +
position: relative !important;
 +
left: 0 !important;
 +
width: 100% !important;
 +
height: auto !important;
 +
}
 +
 +
.box.style1 .image img {
 +
position: relative;
 +
height: auto;
 +
width: 100%;
 +
}
 +
 +
.box.style1 .inner {
 +
margin: 0 !important;
 +
padding: 2em 1.25em 2em 1.25em !important;
 +
}
 +
 +
.box.style2 .inner .row:before {
 +
display: none;
 +
}
 +
 +
.box.style2 .inner .image {
 +
padding: 0;
 +
max-width: 250px;
 +
margin: 0 auto 20px auto;
 +
}
 +
 +
.box.style3 {
 +
padding: 2em 1.25em 2em 1.25em;
 +
}
 +
 +
/* Header */
 +
 +
#header {
 +
padding: 6em 0 6em 0;
 +
}
 +
 +
#header header {
 +
padding-left: 2em;
 +
padding-right: 2em;
 +
}
 +
 +
#header header h1 {
 +
font-size: 1.75em;
 +
letter-spacing: 6px;
 +
}
 +
 +
#header footer {
 +
bottom: 4.5em;
 +
padding: 0 2em 0 2em;
 +
}
 +
 +
#header footer:after {
 +
bottom: -4.5em;
 +
left: 50%;
 +
height: 4.5em;
 +
}
 +
 +
#header footer:before {
 +
width: 45px;
 +
height: 33px;
 +
bottom: -2.25em;
 +
margin-left: -22.5px;
 +
margin-bottom: -16.5px;
 +
background-size: 45px 33px;
 +
}
 +
 +
/* Banner */
 +
 +
#banner {
 +
padding: 3em 2em 3em 2em;
 +
background-size: auto 150%;
 +
}
 +
 +
#banner header {
 +
margin: 0 0 1em 0;
 +
}
 +
 +
#banner header h2 {
 +
font-size: 1.5em;
 +
letter-spacing: 6px;
 +
}
 +
 +
 +
 +
}</style>
 +
 +
 +
 +
 +
<!--[if lte IE 8]><style>
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
#header header p {
 +
border-top: solid 1px #888;
 +
}</style><![endif]-->
 +
</head>
 +
<body>
 +
 +
<!-- Header -->
 +
<section id="header" style="padding: 188px 0px;">
 +
<header>
 +
<h1 style="padding-top: 5px">Warwick iGEM 2015</h1>
 +
<p>Brixells</p>
 +
<br>
 +
<br>
 +
<br>
 +
<br>
 +
<br>
 +
<br>
 +
<br>
 +
<br>
 +
<br>
 +
 +
</header>
 +
<footer><b></b><a href="#home" class="btn btn-default" id="menu-toggle">Skip to Home</a></p>
 +
 +
 +
 +
<a class="button style2 scrolly-middle" href="#banner">Learn about Cell LEGO</a>
 +
 +
 +
</footer><p style="float: right;"><img src="https://static.igem.org/mediawiki/2015/3/3c/WarwickLogoforhome.png" height="200px" width="300px" border="100px"></p>
 +
 +
</section>
 +
 +
<!-- Banner -->
 +
<section id="banner">
 +
 +
<header>
 +
<h2>Brixells<br><br> biological building blocks</h2>
 +
</header>
 +
<p>DNA programmed assembly of cells:
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<br>We are inventing a novel method of producing microscopic cell-cell binding
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<br>using intracellular proteins modified to express on the surface of the cell
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<br>The applications are endless: medicine, micro- and synthetic biology research,
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<br>synthetic organs, insight into multicellularity, meta-material production,
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<br> whatever you can imagine.
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...the Brixell Collection</h2>
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Latest revision as of 18:18, 18 September 2015


Our Submitted Parts
...the Brixell Collection


Click on the image to the right to see what parts we submitted for the competition or continue scrolling.










Our Project

Click on the images below to explore our different sections.

Please Contact Us

We will respond as quickly as possible.