Difference between revisions of "Team:NCTU Formosa"

 
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<P>We are 2015 NCTU_Formosa!</P>
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<P>Abstract</P>
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        <P>Our project focuses on providing a new examination method both prior to and after target drug treatments. By allowing our fluorescent Escherichia coli (E. coli) to display single chain fragment variable (scFv) antibodies on the membrane surface, we hope to enlarge the fluorescence emission during immunostaining tissue or tumor cells in pre-examination. After undergoing treatment, health personnel and patients need to extensively track medicine usage to ensure the target drugs are still effective. </P>
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        <P>Our engineered E. coli allow users to interchange various types of scFv, thus creating several varieties of antibody-antigen detection and further progresses various study fields. For example, the newly created immunobiosensor can help further the medical field due to the effective determination of target drugs.</P>
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        <P>In addition, this E. coli increases the convenience of using assorted modes of currently existing detection machines, such as quartz crystal microbalance (QCM) , surface plasmon resonance (SPR), etcetera. Since our cells are able to efficiently stick on gold surfaces and our receptors can stand on E. coli's surface, the situation of random orientation can be greatly reduced. The theory is that the binding sides of the cell cannot capture the respective molecules commendably even if there is scFv.</P>
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/*圖案*/
  
         <P>As a whole, we provide a feasible and new synthetic biological method for nowadays detection field!</P>
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        <div style="position:absolute;bottom:30%;width:100%;text-align:center;font-size:18pt;letter-spacing:5px;">The only thing we can detect is everything.</div>
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      <div class="photocontent1"><h2>Who we are</h2>
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      NCTU_Formosa created an organization—APOllO, which stands for Almighty Probe of scFv Organization. APOllO is devoted to developing detection technology by utilizing antibodies. In 2015, we cooperated with iGEM to create a brand new detection platform using synthetic biology.</div>
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    <img src="https://static.igem.org/mediawiki/2015/2/2e/NCTU_Formosa_Homepage_antibody.png" align="middle" height=250px>
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      <div class="photocontent1"><h2>What's new</h2>
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APOllO E.Cotector:<br> 
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Our organization creates a customized scFv detection platform by co-transforming any desired plasmid in to <i>E. coli</i>. ScFv utilizes antigen-antibody interaction to act as probes. Therefore, our E.Cotector has the function of a detector.
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        <div class="photocontent1"><h2>What we care about</h2>
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In 2015, we focused on helping doctors select appropriate candidates for monoclonal-antibody targeted drug treatments—reducing the price of patients' treatment. If the cost for diagnosis decreases, more patients can afford it. Therefore lowering the mortality rate of cancer. <br>
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        <div style="position:absolute;bottom:17vh;right:20vw;font-size:20pt;"><a href="https://2015.igem.org/Team:NCTU_Formosa/Project" style="color:#000;"><u>Get Ready to Explore</a></U></div>
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Latest revision as of 02:41, 19 September 2015

The only thing we can detect is everything.

Who we are

NCTU_Formosa created an organization—APOllO, which stands for Almighty Probe of scFv Organization. APOllO is devoted to developing detection technology by utilizing antibodies. In 2015, we cooperated with iGEM to create a brand new detection platform using synthetic biology.

What's new

APOllO E.Cotector:
Our organization creates a customized scFv detection platform by co-transforming any desired plasmid in to E. coli. ScFv utilizes antigen-antibody interaction to act as probes. Therefore, our E.Cotector has the function of a detector.

What we care about

In 2015, we focused on helping doctors select appropriate candidates for monoclonal-antibody targeted drug treatments—reducing the price of patients' treatment. If the cost for diagnosis decreases, more patients can afford it. Therefore lowering the mortality rate of cancer.