Difference between revisions of "Team:KU Leuven/Research"

 
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<h2>Research</h2>
 
<h2>Research</h2>
 
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  <img src="https://static.igem.org/mediawiki/2015/1/1d/KU_Leuven_Arrows_wiki.png" alt="Scroll down" width="100%">
 
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<a href="https://twitter.com/kuleuven_igem" height="100%"><img src="https://static.igem.org/mediawiki/2015/b/b8/KU_Leuven_Twitter-logo.png" alt="Twitter" width="100%"></a>   
 
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<a href="https://www.facebook.com/KULeuveniGEM?fref=ts" alt="Facebook" height="50px"><img src="https://static.igem.org/mediawiki/2015/d/df/KU_Leuven_Fblogo.png" alt="mail" width="100%"></a>   
 
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<div id="summarylogomail">
 
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<a href="mailto:igem@chem.kuleuven.be"><img src="https://static.igem.org/mediawiki/2015/1/11/KU_Leuven_mail.png" alt="mail" width="50px"></a>   
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<a href="mailto:igem@chem.kuleuven.be"><img src="https://static.igem.org/mediawiki/2015/1/11/KU_Leuven_mail.png" alt="mail" width="100%"></a>   
 
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<div class="summary">
 
<div class="summary">
 
<p>
 
<p>
We designed a circuit capable of forming patterns in a controlled way. Using a modified and temperature-sensitive lambda repressor (cI), we can trigger formation at desired points in time. This time-dependent controllability, together with the possibility to change many different parameters and output signals, leads to an enormous tunability in the creation of the patterns. Our mechanism will stimulate advancements in a variety of industrial processes like the creation of novel bio-materials. This fundamental project could also speed up medical research projects like tumor formation and tissue regeneration.  
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We designed a circuit capable of forming patterns in a controlled way. Using a modified and temperature-sensitive lambda repressor (cI), we can trigger formation at desired points in time. This time-dependent controllability, together with the possibility to change many different parameters and output signals, leads to an enormous tunability in the creation of the patterns. Our mechanism will stimulate advancements in a variety of industrial processes like the creation of novel bio-materials. This fundamental project could also speed up medical research projects like tumor formation.  
 
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Idea">
  <img src="https://static.igem.org/mediawiki/2015/4/4d/KU_Leuven_scheme_pattern_formation.png" width="95%" >
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Methods">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Idea">
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<h2>Idea</h2>
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<p> A detailed description about the interaction between our two cells and the genetic circuit can be found here.
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</p>
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  <img src="https://static.igem.org/mediawiki/2015/3/32/KU_Leuven_AgarPlates.jpg" width="100%">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Methods">
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  <h2>Methods</h2>
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<p> Besides an overview of the performed steps to create two different cell types, you can also find a description of the detailed protein quantification methods to determine interesting parameters.
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</p>
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<img src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png" height="40%" width="85%" alt="Read more">
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<img src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png" height="40%" width="85%" alt="Read more">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Basic_Part">
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  <img src="https://static.igem.org/mediawiki/2015/e/e6/KU_Leuven_Wiki_Button_-_Parts2.png" width="100%">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Results">
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<img src="https://static.igem.org/mediawiki/2015/e/e0/KU_Leuven_Wiki_Button_-_Results2.png" width="100%">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Idea">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Basic_Part">
  <h2>Idea</h2>
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  <h2>Basic Parts</h2>
  <p> A detailed description about the interaction between our two cells and the genetic circuit can be found here.
+
  <p> Our new, self-designed basic parts necessary to control cell-cell interactions and <i>E. Coli</i> motility.</p>
<br/>
+
<div class="more"><p>Read more</p></div>
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</p>
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</a>
 
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<div class="subtext">
 
<div class="subtext">
  <h2>Parts</h2>
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Composite_Part">
<p>
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  <h2>Composite Parts</h2>
More coming soon
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<p> Our basic parts were combined with each other and with existing iGEM promotors, RBS and terminators.
 
</p>
 
</p>
<!---------<p>A list of all used biobricks, the modifications we performed on them and the new ones we designed.
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</a>
<br/>
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<a href="https://2015.igem.org/Team:KU_Leuven/Project/About">Read more</a>
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</p>------->
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<div class="subtext">
  <h2>Methods</h2>
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Results">
<p>
+
  <h2>Results</h2>
More coming soon
+
<p> The results of our experiments will appear here.
 
</p>
 
</p>
<!---<p>Here you can find the performed steps to create two different cell types and detailed quantification methods to determine interesting parameters
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</a>
<br/>
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</div>
<a href="https://2015.igem.org/Team:KU_Leuven/Project/About">Read more</a>
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</p>----->
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<img src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png" height="40%" width="85%" alt="Read more">
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<img src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png" height="40%" width="85%" alt="Read more">
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<div class="subtext">
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<!------
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<a href="https://2015.igem.org/Team:KU_Leuven/Project/About">---->
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<h2>Results</h2>
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<div class="subimgrm">
<p>
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Results">
More coming soon
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<div id="more">
</p>
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<img src="https://static.igem.org/mediawiki/2015/7/73/KUL_Wiki_Button_-_Read_more.png" height="40%" width="85%" alt="Read more">
<!--------<p>The results of our experiments will appear here.
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Read more</p>
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    <b>Idea</b>
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<img src="https://static.igem.org/mediawiki/2015/5/5e/KU_Leuven_Wiki_Button_-_Idea2.png" width="100%" ></a>
 
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      <a href="https://2015.igem.org/Team:KU_Leuven/Research/Idea" >
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        <p>
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          A detailed description about the interaction between our two cells and the genetic circuit can be found here.
 +
        </p>
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    </a>
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  </div>
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</div>
  
<div class="center" id="footer">
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<div class="sponsorsleft">
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  <a href="https://www.eppendorf.com/BE-en/">
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  <img src="https://static.igem.org/mediawiki/2015/d/d3/KU_Leuven_LOGO_Eppendorf2.jpg" alt="Eppendorf" width="100%">
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  </a>
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Methods" >
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    <b>Methods</b>
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<img src="https://static.igem.org/mediawiki/2015/1/1a/KU_Leuven_Wiki_Button_-_Methods2.png" width="100%" ></a>
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      <a href="https://2015.igem.org/Team:KU_Leuven/Research/Methods" >
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        <p>
 +
Besides an overview of the performed steps to create two different cell types, you can also find a description of the detailed protein quantification methods to determine interesting parameters.
 +
        </p>
 +
    </a>  
 
   </div>
 
   </div>
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</div>
  
<div id="bioke">
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<div class="subimgrowm">
  <a href="https://www.bioke.com/">
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<div class="whiterow">
  <img src="https://static.igem.org/mediawiki/2015/2/23/KU_Leuven_LOGO_Bioke.jpg" alt="Bioké" width="100%">
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  </a>
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</div>
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<div class="subimgrowm">
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<div class="subimgm">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Basic_Part" >
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    <b>Basic Parts</b>
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<img src="https://static.igem.org/mediawiki/2015/e/e6/KU_Leuven_Wiki_Button_-_Parts2.png" width="100%" ></a>
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      <a href="https://2015.igem.org/Team:KU_Leuven/Research/Basic_Part" >
 +
        <p>
 +
          Our new, self-designed basic parts necessary to control cell-cell interactions and <i>E. Coli</i> motility.
 +
        </p>
 +
    </a>  
 
   </div>
 
   </div>
 
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</div>
<div id="kuleuven">
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  <a href="http://www.kuleuven.be/">
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<div class="subimgrowm">
  <img src="https://static.igem.org/mediawiki/2015/0/08/KULEUVEN_groot.png" alt="bioSCENTer" width="100%">
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<div class="whiterow">
  </a>
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</div>
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</div>
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<div class="subimgrowm">
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<div class="subimgm">
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Composite_Part" >
 +
    <b>Composite Parts</b>
 +
<img src="https://static.igem.org/mediawiki/2015/0/08/KU_Leuven_Wiki_Button_-_Composite_parts2.png" width="100%" ></a>
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</div>
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<div class="whitespace">
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</div>
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  <div class="subtextm">
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      <a href="https://2015.igem.org/Team:KU_Leuven/Research/Composite_Part" >
 +
        <p>
 +
          Our basic parts were combined with each other and with existing iGEM promotors, RBS and terminators.
 +
        </p>
 +
    </a>  
 
   </div>
 
   </div>
 
+
</div>
<div id="LRD">
+
 
  <a href="http://lrd.kuleuven.be/">
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  <img src="https://static.igem.org/mediawiki/2015/b/b4/KU_Leuven_HR_LRD_CMYK_LOGO.jpg" alt="KU Leuven Research & Development" width="100%">
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  </a>
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<div class="whiterow">
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<div id="youreca">
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  <a href="http://www.kuleuven.be/onderzoek/youreca/">
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<div class="subimgrowm">
  <img src="https://static.igem.org/mediawiki/2015/4/4f/KU_Leuven_YOURECA.png" alt="YOURECA" width="100%">
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<div class="subimgm">
  </a>
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<a href="https://2015.igem.org/Team:KU_Leuven/Research/Results" >
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    <b>Results</b>
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<img src="https://static.igem.org/mediawiki/2015/e/e0/KU_Leuven_Wiki_Button_-_Results2.png" width="100%" ></a>
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      <a href="https://2015.igem.org/Team:KU_Leuven/Research/Results" >
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        <p>
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        Click here to discover our results
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        </p>
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    </a>  
 
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<h3> Contact </h3>
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<p style="font-size:1.3em; text-align: center">
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Address: Celestijnenlaan 200G room 00.08 - 3001 Heverlee<br>
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Telephone: +32(0)16 32 73 19<br>
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Email: igem@chem.kuleuven.be<br>  
 
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Latest revision as of 09:33, 20 October 2015

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We designed a circuit capable of forming patterns in a controlled way. Using a modified and temperature-sensitive lambda repressor (cI), we can trigger formation at desired points in time. This time-dependent controllability, together with the possibility to change many different parameters and output signals, leads to an enormous tunability in the creation of the patterns. Our mechanism will stimulate advancements in a variety of industrial processes like the creation of novel bio-materials. This fundamental project could also speed up medical research projects like tumor formation.





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Address: Celestijnenlaan 200G room 00.08 - 3001 Heverlee
Telephone: +32(0)16 32 73 19
Email: igem@chem.kuleuven.be