Difference between revisions of "Team:Valencia UPV"

 
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<p align = "center"><font size = 5> AladDNA </font></p>
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<h4><p align = "center"><font size = 3> It makes your wishes come true! </font></p></h4>
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          <h1>AladDNA</h1>
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          <figure>
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<img src="https://static.igem.org/mediawiki/2015/7/72/ValenciaUPVMain1.png">
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<img src="https://static.igem.org/mediawiki/2015/9/97/ValenciaUPVMain2.png">
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<img src="https://static.igem.org/mediawiki/2015/2/24/ValenciaUPVMain3.png">
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<img src="https://static.igem.org/mediawiki/2015/7/72/ValenciaUPVMain1.png">
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<img src="https://static.igem.org/mediawiki/2015/9/97/ValenciaUPVMain2.png">
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<style>  
  
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<p>aIf you compared an old mobile phone from 20 years ago, to a new one, the main differences would be the huge improvement of its capabilities and their amazing miniaturization. This multitask feature, provides us with small devices which manage bigger and bigger amounts of information.</p>
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<p>So, why not to apply this strategy in biology? The goal of our project is to develop a biosystem that could work as a source of plenty different compounds, depending on the user’s election. It doesn’t matter where you are, or what you need, because AladDNA will provide you with it! Just pick your product and let there be light, literally!</p
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<p>This idea is the result of tones of brainstorming hours. Let us introduce you a bit more the problem and explain why we chose this system.</p>
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<h4>The problem </h4>
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<p>Producing materials in all countries involve the creation of huge factories, enormous quantities of raw material and high costs for transporting the entire production; this is a huge problem, specially for non-accessible areas or regions where it is impossible to create a factory, as space stations.</p>
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<div align="center"><img src="https://static.igem.org/mediawiki/2015/1/17/Fabrica.png" align ="middle" width=674 height=232/></div>
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<h4>The idea</h4>
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<p> So is there any object that produces utilities from raw material? Maybe a kind of Magic lamp? That is what we want to create in Valencia_UPV! Miniaturization of a factory to its minimum expression thanks to Genetic Engineering.</p>
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<div align="center"><img src="https://static.igem.org/mediawiki/2015/a/a0/Info2dna.png" width=391 height=188></div>
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<h4>The solution</h4>
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<p>In order to create lots of different products from a single media, we have designed a biological circuit that allows plants to change their metabolic pathway thanks to light stimulus. It is a two-steps optogenetically controlled cascade, activated with red or blue light.</p>
 
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<p>With this technology we can avoid using chemicals for changing the metabolic pathway and produce nearly anything we want in the cell, what is more, this can be virtually expanded to infinite, allowing the creation of several different compounds just with one machine.</p>
 
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<img src="https://static.igem.org/mediawiki/2015/a/a8/Alpha.png" width=268 height=168 style="float:left">
 
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<p>The chassis for the experiment are plants, but why plants? They need light to grow, so maybe they aren’t the best organism for optogenetics, aren’t they?</p>
 
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<p>In their primary growth steps, light is not needed, and, what is more, seeds are very resistant to unfavorable environments, so this allows us the creation of a gadget that keeps the seeds inside and which can be used in many different environments, from the dessert to the space. Just pressing a button, the gadget can be programmed to stimulate the plant with the correct sequence of light and with the enough intensity and time thanks to LEDs technology.</p>
 
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<p>We are trying to produce some small proteins such as interferon alpha, a rotavirus vaccine, a cholera vaccine and lactoferrin, compounds that can be useful in underdeveloped countries, but keep in mind that the range of possibilities is enormous.</p>
 
  
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<h4><p align = "center"> Mix a little bit of biology with another bit of engineering sauce and add the magic touch to create AladDNA, the GENEious that will make your wishes come true!</p></h4>
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<div align="center"><img src="https://static.igem.org/mediawiki/2015/8/81/Genio%2Bcolores.png" width=400 height=400></div>
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<h4>You can follow us on: </h4>
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<li> <a href="https://www.facebook.com/ValenciaUPViGEM2015"><font color="0e1f5b"> Facebook page </font></a></li>
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<li> <a href="https://twitter.com/UPVigem"><font color="00aced"> Twitter page </font></a></li>
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<li> <a href="https://plus.google.com/110318939646477138807/"><font color="d34836"> Google+ page </font> </a></li>
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<li> <a href="mailto: valencia.upv.igem@gmail.com"><font color="008000"> Email us: valencia.upv.igem@gmail.com </font> </a></li>
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<h4> Editing your wiki </h4>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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div#slider figure img { width: 20%; float: left; height: 508px;}
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<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:Valencia_UPV&action=edit"> Click here to edit this page! </a></p>
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<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>
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<h4>Templates </h4>
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<p> This year we have created templates for teams to use freely. More information on how to use and edit the templates can be found on the
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<a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation </a> page.</p>  
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</section>
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<!-- Main -->
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<section id="main" style="padding:4em 0 0 0" class="container">
  
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<div class="row" style="font-size:initial">
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<div class="12u">
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<section class="box">
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<header class="major">
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<h2>Jamboree Results!<br />
  
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<h4>Tips</h4>
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</h2><hr>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<ul>
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<br>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<div style="float:left"><img src="https://static.igem.org/mediawiki/2015/8/8f/Valencia_upv_teamjamboree.jpeg" style="width:20em; margin-right: 2em"></div>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<br><p>In the 2015 Giant Jamboree we had a great time, learned an incredible amount of SynBio, and won a <b style="color:#FFD700">GOLD MEDAL!</b> Other teams were deeply attracted by our <a href="https://2015.igem.org/Team:Valencia_UPV/Practices/Minecraft">SynBiocraft</a> Minecraft mod, the light of our bioreactor model with <a href="https://2015.igem.org/Team:Valencia_UPV/Design">magic lamp</a> shape, and judges had a very positive valoration of our presentation and our <a href="https://2015.igem.org/Team:Valencia_UPV/Circuit">biological decoder</a>, the star of our project. Don't hesitate on checking our webpage. Enjoy your travel through the Valencia UPV iGEM project.</p>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away. </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2015.igem.org/Calendar_of_Events">iGEM 2015 calendar</a> </li>
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<li>Have lots of fun! </li>
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</ul>  
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<h4>Inspiration</h4>
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</section>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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</div>
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<ul>
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</div>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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</ul>
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<h4> Uploading pictures and files </h4>
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<div class="row" style="font-size:initial">
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<p> You can upload your pictures and files to the iGEM 2015 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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<div class="12u">
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When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<section class="box">
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<header class="major">
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<h2>AladDNA<br />
  
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<a href="https://2015.igem.org/Special:Upload">CLICK HERE TO UPLOAD FILES</a>
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</h2><hr>
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</header>
  
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<p>
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Conventional bioproduction methods require huge and specialized infrastructures for each new product, difficulting the fulfilment of the manufacturing needs in remote locations. What if we could just send information that could unfold on site? AladDNA is an innovative genetic design aimed to encode the manufacturing instructions for several bioproducts as genetic information. It is also capable to process this information on demand as single output products in response to the user´s wishes. Just like a genie in a lamp!  </p>
  
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<p>This system uses DNA to store information inside a plant seed, acting as a miniaturized and flexible biofactory capable of producing different bioproducts such as interferon alpha or anti-choleric vaccines. Equipped with an optogenetically controlled decoder, AladDNA can activate the production of different high-added value products upon the reception of external signals based on combinations of light stimuli. AladDNA allows bioproduction in any condition avoiding prohibitive costs due to infrastructures.  </p>
  
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<p> <div style="text-align: center;"><h7><b><i>No matter where you are or what you need, just ask your wish!</i></b></h7></div> </p>
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<p> <div style="text-align: center;"><h7><b><i> Because AladDNA has no frontiers!</i></b></h7></div>  
  
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<img style="height: 23.5em;" src="https://static.igem.org/mediawiki/2015/b/b8/ValenciaUPV_HOME_3IDEAS.png"></a>
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<figcaption>
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<a href="https://2015.igem.org/Team:Valencia_UPV/Description" style="text-decoration: none;">
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<h3>Check here to meet our biological circuit</h3>
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</figcaption>
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</figure>
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</span>
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<h3>Project overview</h3>
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<ul class="actions">
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<li><a href="https://2015.igem.org/Team:Valencia_UPV/Description" class="button alt">Learn More</a></li>
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" src="https://static.igem.org/mediawiki/2015/6/64/UPV_fotobomb.png"></a>
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<figcaption>
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<a href="https://2015.igem.org/Team:Valencia_UPV/Modeling" style="text-decoration: none;">
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<h3>Great circuit, great modeling</h3>
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</figcaption>
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</figure>
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</span>
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<h3>Modeling</h3>
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<ul class="actions">
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<li><a href="https://2015.igem.org/Team:Valencia_UPV/Modeling" class="button alt">Learn More</a></li>
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<img src="https://static.igem.org/mediawiki/2015/7/7d/Valencia_upv_lamparabuena.png"></a>
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<figcaption>
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<a href="https://2015.igem.org/Team:Valencia_UPV/Design" style="text-decoration: none;">
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<h3>Discover our magic lamp</h3>
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</figcaption>
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</figure>
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</span>
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<h3>The device</h3>
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<ul class="actions">
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<li><a href="https://2015.igem.org/Team:Valencia_UPV/Design" class="button alt">Learn More</a></li>
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<img src="https://static.igem.org/mediawiki/2015/4/42/Valencia_UPV_ConstruccionFinal.png" style="height: 22.2em;"></a>
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<figcaption>
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<a href="https://2015.igem.org/Team:Valencia_UPV/Practices/Minecraft" style="text-decoration: none;">
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<h3>The treasure of our policy and practices</h3>
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</figcaption>
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</figure>
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</span>
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<h3>SynbioCraft</h3>
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<ul class="actions">
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<li><a href="https://2015.igem.org/Team:Valencia_UPV/Practices/Minecraft" class="button alt">Learn More</a></li>
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Latest revision as of 02:05, 20 November 2015

Valencia UPV iGEM 2015

Jamboree Results!



In the 2015 Giant Jamboree we had a great time, learned an incredible amount of SynBio, and won a GOLD MEDAL! Other teams were deeply attracted by our SynBiocraft Minecraft mod, the light of our bioreactor model with magic lamp shape, and judges had a very positive valoration of our presentation and our biological decoder, the star of our project. Don't hesitate on checking our webpage. Enjoy your travel through the Valencia UPV iGEM project.

AladDNA

Conventional bioproduction methods require huge and specialized infrastructures for each new product, difficulting the fulfilment of the manufacturing needs in remote locations. What if we could just send information that could unfold on site? AladDNA is an innovative genetic design aimed to encode the manufacturing instructions for several bioproducts as genetic information. It is also capable to process this information on demand as single output products in response to the user´s wishes. Just like a genie in a lamp!

This system uses DNA to store information inside a plant seed, acting as a miniaturized and flexible biofactory capable of producing different bioproducts such as interferon alpha or anti-choleric vaccines. Equipped with an optogenetically controlled decoder, AladDNA can activate the production of different high-added value products upon the reception of external signals based on combinations of light stimuli. AladDNA allows bioproduction in any condition avoiding prohibitive costs due to infrastructures.

No matter where you are or what you need, just ask your wish!

Because AladDNA has no frontiers!

Check here to meet our biological circuit

Project overview

Great circuit, great modeling

Modeling

Discover our magic lamp

The device

The treasure of our policy and practices

SynbioCraft