Difference between revisions of "Team:AHUT China/Description"

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<script src="https://2015.igem.org/Team:AHUT_China/jquery?action=raw&ctype=text/javascript" type="text/javascript" ></script>
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<div id="index_main">
  
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<h2> Project Description </h2>
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  <div id="top_navi">
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    <ul id="index_top_navi">
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        <li><a href="https://2015.igem.org/Team:AHUT_China/team">TEAM</a></li>
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        <li><a href="https://2015.igem.org/Team:AHUT_China/parts">PARTS</a></li>
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        <li><a href="https://2015.igem.org/Team:AHUT_China/project">PROJECT</a></li>
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        <li><a href="https://2015.igem.org/Team:AHUT_China/Practices">HUMAN PRACTICES</a></li>
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        <li><a href="https://2015.igem.org/Team:AHUT_China/safety">SAFETY</a></li>
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        <li><a href="https://2015.igem.org/Team:AHUT_China/notebook">NOTEBOOK</a></li>
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      </ul>
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      <div style="position:absolute; top:52px; left:50%; margin-left:400px;">
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        <a href=""><img src="https://static.igem.org/mediawiki/2015/a/a0/AHUT_CHINA_2015_clock.gif" width="200" height="145" alt=""/></a>
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      </div>
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<p>Tell us about your project, describe what moves you and why this is something important for your team.</p>
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<br />
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      <img src="https://static.igem.org/mediawiki/2015/d/dc/AHUT_CHINA_2015_index_chinese.png" width="166" height="299" alt=""/>
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      <img src="https://static.igem.org/mediawiki/2015/e/e6/AHUT_CHINA_2015_index_dihuang.png" width="289" height="258" alt=""/>
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    <div style="margin:0 auto; width:456px; height:95px;padding-top:20px;">
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      <img src="https://static.igem.org/mediawiki/2015/c/c7/AHUT_CHINA_2015_index_team_name.png" width="456" height="95" alt=""/>
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<h5>What should this page contain?</h5>
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  <div class="index_block" id="index_block1">
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<li> A clear and concise description of your project.</li>
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    <p style="width:460px; font-size:18px; line-height:30px; padding-top:50px; padding-left:500px; color:#fff; margin:0 auto; text-align:justify; font-family:Arial, Helvetica, sans-serif;">
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<li>A detailed explanation of why your team chose to work on this particular project.</li>
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          Many foods and medicines can benefit human beings with their significant physiological activity mainly because of APeGs contained in them. APeGs has prominent health functions such as anti-oxidation, anti-aging, and liver and neuro protection. It plays an extremely important role in our health protection.  </br>
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<li>References and sources to document your research.</li>
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          APeGs is a general term for a category of compounds. It widely exists in many plant ingredients such as broadleaf holly leaf, osmanthus fragrans, olive, etc; in Pharmacopoeia of the People's Republic of China, it also serves as main efficacy component and quality control standard of many traditional Chinese medicines such as cistanche, beautyberry leaf, semen plantaginis, Rehmannia glutinosa Libosch, forsythia, etc.
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<li>Use illustrations and other visual resources to explain your project.</li>
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    </p>
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  <div class="index_block" id="index_block2">
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    <p style="width:560px; height:500px; font-size:18px; line-height:36px; padding-top:50px; padding-right:400px; color:#676767; margin:0 auto; text-align:justify;font-family:Arial, Helvetica, sans-serif; background:url(https://static.igem.org/mediawiki/2015/d/d2/AHUT_CHINA_2015_Rehmannia.png) right no-repeat;">
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However, in most foods and medicines, the contents of APeGs are very low and significantly diverse, making APeGs’ quality cannot be guaranteed. We are expecting to find a much more stable and effective way to regulate and control its effective production with the view of getting foods and medicines of better quality.</br>
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We have chosen Rehmannia glutinosa Libosch which contains rich APeGs as our study object. We try to regulate and control its metabolic pathway through the key nodes in Rehmannia glutinosa Libosch to study influences on metabolites exerted by different ways of regulation and control.
  
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<h4>Advice on writing your Project Description</h4>
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      In order to better conduct our experiments and project, we’ve started with the study on the first key enzyme PAL in the synthetic pathway of APeGs. We transferred the gene RgPAL1 to highly express PAL, and study its influence on APeGs. The result shows that part of APeGs enrichment can be gained by raising PAL. It serves as the first key node in our network of regulation and control pathways, and has laid a good foundation for our later study on the network of metabolic regulation and control.
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We encourage you to put up a lot of information and content on your wiki, but we also encourage you to include summaries as much as possible. If you think of the sections in your project description as the sections in a publication, you should try to be consist, accurate and unambiguous in your achievements.
 
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Judges like to read your wiki and know exactly what you have achieved. This is how you should think about these sections; from the point of view of the judge evaluating you at the end of the year.
 
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<h4>References</h4>
 
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<p>iGEM teams are encouraged to record references you use during the course of your research. They should be posted somewhere on your wiki so that judges and other visitors can see how you though about your project and what works inspired you.</p>
 
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<h4>Inspiration</h4>
 
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<p>See how other teams have described and presented their projects: </p>
 
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<li><a href="https://2014.igem.org/Team:Imperial/Project"> Imperial</a></li>
 
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<li><a href="https://2014.igem.org/Team:UC_Davis/Project_Overview"> UC Davis</a></li>
 
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<li><a href="https://2014.igem.org/Team:SYSU-Software/Overview">SYSU Software</a></li>
 
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Latest revision as of 06:05, 17 September 2015

Many foods and medicines can benefit human beings with their significant physiological activity mainly because of APeGs contained in them. APeGs has prominent health functions such as anti-oxidation, anti-aging, and liver and neuro protection. It plays an extremely important role in our health protection.
APeGs is a general term for a category of compounds. It widely exists in many plant ingredients such as broadleaf holly leaf, osmanthus fragrans, olive, etc; in Pharmacopoeia of the People's Republic of China, it also serves as main efficacy component and quality control standard of many traditional Chinese medicines such as cistanche, beautyberry leaf, semen plantaginis, Rehmannia glutinosa Libosch, forsythia, etc.

However, in most foods and medicines, the contents of APeGs are very low and significantly diverse, making APeGs’ quality cannot be guaranteed. We are expecting to find a much more stable and effective way to regulate and control its effective production with the view of getting foods and medicines of better quality.
We have chosen Rehmannia glutinosa Libosch which contains rich APeGs as our study object. We try to regulate and control its metabolic pathway through the key nodes in Rehmannia glutinosa Libosch to study influences on metabolites exerted by different ways of regulation and control.

In order to better conduct our experiments and project, we’ve started with the study on the first key enzyme PAL in the synthetic pathway of APeGs. We transferred the gene RgPAL1 to highly express PAL, and study its influence on APeGs. The result shows that part of APeGs enrichment can be gained by raising PAL. It serves as the first key node in our network of regulation and control pathways, and has laid a good foundation for our later study on the network of metabolic regulation and control.