Difference between revisions of "Team:DTU-Denmark"

Line 49: Line 49:
 
         <div class="collapse navbar-collapse" id="nav-collapse">
 
         <div class="collapse navbar-collapse" id="nav-collapse">
 
           <ul class="nav navbar-nav">
 
           <ul class="nav navbar-nav">
<li class="active">
+
<li >
 
<a href="/Team:DTU-Denmark"
 
<a href="/Team:DTU-Denmark"
 
  >Home
 
  >Home
 
                                           </a></li>
 
                                           </a></li>
<li  
+
<li class="active">
+
                   
+
                 
+
                   
+
                 
+
  >
+
 
<a href="/Team:DTU-Denmark"
 
<a href="/Team:DTU-Denmark"
 
  class="dropdown-toggle"
 
  class="dropdown-toggle"
Line 135: Line 129:
 
<li >
 
<li >
 
<a href="/Team:DTU-Denmark/Project/POC_MAGE"
 
<a href="/Team:DTU-Denmark/Project/POC_MAGE"
  >POC of Mage in B.S.
+
  >Proof of concept of MAGE in B. subtilis
 
                                           </a></li></ul></li>
 
                                           </a></li></ul></li>
 
<li >
 
<li >
Line 204: Line 198:
 
       <div class="container-fluid" id="scrollspy">
 
       <div class="container-fluid" id="scrollspy">
 
         <ul class="nav navbar-nav">
 
         <ul class="nav navbar-nav">
           <li><a class="page-scroll" href="#Project-description">Project description</a></li><li><a class="page-scroll" href="#Social-Media">Social Media</a></li><li><a class="page-scroll" href="#Overview">Overview</a></li><li><a class="page-scroll" href="#Sitemap">Sitemap</a></li>
+
            
 
         </ul>
 
         </ul>
 
       </div>
 
       </div>
Line 218: Line 212:
 
           <div class="col-md-12">
 
           <div class="col-md-12">
 
              
 
              
             <h3>Technical University of Denmark</h3>
+
             <h3><br></h3>
             <h1>The Synthesizer</h1>
+
             <h1>Team and Attributions</h1>
 
              
 
              
 
             <hr/>
 
             <hr/>
 
             <ul class="list-inline hidden-xs hidden-sm">
 
             <ul class="list-inline hidden-xs hidden-sm">
             
 
              <li>
 
                <a id="Project-description-submenu" class="btn btn-default btn-transparent btn-lg page-scroll" href="#Project-description">Project description</a>
 
              </li>
 
             
 
              <li>
 
                <a id="Social-Media-submenu" class="btn btn-default btn-transparent btn-lg page-scroll" href="#Social-Media">Social Media</a>
 
              </li>
 
             
 
              <li>
 
                <a id="Overview-submenu" class="btn btn-default btn-transparent btn-lg page-scroll" href="#Overview">Overview</a>
 
              </li>
 
             
 
              <li>
 
                <a id="Sitemap-submenu" class="btn btn-default btn-transparent btn-lg page-scroll" href="#Sitemap">Sitemap</a>
 
              </li>
 
 
                
 
                
 
             </ul>
 
             </ul>
 
             <ul class="list-inline visible-xs visible-sm">
 
             <ul class="list-inline visible-xs visible-sm">
             
 
              <li>
 
                <a id="Project-description-submenu" class="page-scroll" href="#Project-description">Project description</a>
 
              </li>
 
             
 
              <li>
 
                <a id="Social-Media-submenu" class="page-scroll" href="#Social-Media">Social Media</a>
 
              </li>
 
             
 
              <li>
 
                <a id="Overview-submenu" class="page-scroll" href="#Overview">Overview</a>
 
              </li>
 
             
 
              <li>
 
                <a id="Sitemap-submenu" class="page-scroll" href="#Sitemap">Sitemap</a>
 
              </li>
 
 
                
 
                
 
             </ul>
 
             </ul>
Line 265: Line 227:
 
           <div class="col-md-12">
 
           <div class="col-md-12">
 
             Scroll down for more<br>
 
             Scroll down for more<br>
             <a href="#Project-description" class="btn btn-circle btn-transparent page-scroll">
+
             <a href="#" class="btn btn-circle btn-transparent page-scroll">
 
               <i class="fa fa-angle-double-down"></i>
 
               <i class="fa fa-angle-double-down"></i>
 
             </a>
 
             </a>
Line 273: Line 235:
 
     </div>
 
     </div>
 
      
 
      
 
<div id="Project-description">
 
  <div class="container">
 
    <div class="row col-md-12">
 
      <h1>
 
        Project description
 
      </h1>
 
      <p style="text-align: center;"><span style="font-size:72px;"><span class="fa fa-headphones" style="color:rgb(0, 0, 0);"></span></span></p>
 
 
<p style="text-align: center;">Tune in and listen to The Synthesizers podcast explaining our project in 20 seconds, 5 minutes, or 10 minutes</p>
 
 
<p style="text-align: center;"><img alt="" src="/wiki/images/7/7d/DTU-Denmark_drawingpng.png" style="width: 625px; height: 378px;" /></p>
 
 
<p>Non-ribosomal peptides have important anti-bacterial, anti-cancer, and immunosuppressive biological activities. They are synthesized by modular, high molecular weight enzymes that assemble more than 500 different amino acid substrates in an assembly line manner. For this reason, synthetic biologists have tried to engineer these proteins and to switch modules to create analogs and novel natural products, but with little success. Despite being modular, the interactions between modules have evolved to be highly specific, making synthetic Non-Ribosomal Peptide Synthases (NRPS) a challenge to engineer. Instead of switching modules we introduced a recombination system targeting oligo integration in Bacillus subtilis. We used the recombineering system to alter the active sites determining substrate specificity, thereby creating variants of antibiotics. Our focus was the tyrocidine antibiotic, which cannot be used intravenously due to its toxicity. Our goal is to create new analogs through multiplex automated genome engineering to reduce toxicity.</p>
 
 
<p>&nbsp;</p>
 
 
    </div>
 
  </div>
 
</div>
 
 
 
<div id="Social-Media">
 
  <div class="container">
 
    <div class="row col-md-12">
 
      <h1>
 
        Social Media
 
      </h1>
 
      <div class="col-md-6">
 
<p><a class="twitter-timeline" data-widget-id="631150747221139456" href="https://twitter.com/iGEM_DTU">Tweets by @iGEM_DTU</a> <script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script></p>
 
</div>
 
<div class="col-md-6">
 
<div class="fb-page" data-adapt-container-width="true" data-height="600" data-hide-cover="false" data-href="https://www.facebook.com/dtubiobuilders" data-show-facepile="true" data-show-posts="true" data-small-header="false">
 
<div class="fb-xfbml-parse-ignore">
 
<blockquote cite="https://www.facebook.com/dtubiobuilders"><a href="https://www.facebook.com/dtubiobuilders">DTU Biobuilders</a></blockquote>
 
</div>
 
</div>
 
</div>
 
 
    </div>
 
  </div>
 
</div>
 
 
 
<div id="Overview">
 
  <div class="container">
 
    <div class="row col-md-12">
 
      <h1>
 
        Overview
 
      </h1>
 
      <p>Overview stuff</p>
 
 
    </div>
 
  </div>
 
</div>
 
 
 
<div id="Sitemap">
 
  <div class="container">
 
    <div class="row col-md-12">
 
      <h1>
 
        Sitemap
 
      </h1>
 
      <p>TODO</p>
 
 
    </div>
 
  </div>
 
</div>
 
 
 
     <div class="container">
 
     <div class="container">
 
       <div class="row">
 
       <div class="row">

Revision as of 01:14, 19 September 2015


Team and Attributions


Scroll down for more
Technical University of Denmark
Department of Systems Biology
Søltofts Plads 221
2800 Kgs. Lyngby
Denmark
P: +45 45 25 25 25
M: dtu-igem-2015@googlegroups.com