The Future of the Standard Registry of Biological Parts
The Registry of Standard Biological Parts has been a longstanding partner of iGEM. The promotion of synthetic biology communication and cooperation have become tenants of every iGEM team. The database was an incredible step forward in biological research and standardization. And for this reason, we must now reevaluate the registry. Insulin: Basic Background
• What is the role of Insulin in the Human body?
Insulin is a hormone produced by the pancreas that removes glucose from the blood. In healthy individuals, excess glucose is readily removed from the blood stream by a proportional production of insulin. In persons with diabetes mellitus however; the body is either resistant to insulin, or it has a reduced capacity to produce insulin. Those individuals require an external source of insulin.
• Why are we expressing human Insulin?
The ability to produce recombinant human Insulin cheaply has long been a lucrative goal. There are millions of people worldwide who are dependent on Insulin derived from production methods that make the product expensive -and further yet- potentially dangerous.Our team thinks that the current production methods for human Insulin are inefficient and can be optimized by being expressed in Pichia pastoris.
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