Difference between revisions of "Team:Pasteur Paris"

 
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{{:Team:Pasteur_Paris/Template:Home}}
 
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<p id="Abstract"></p>
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<br>
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<h1 style="text-decoration: none; background-color: #0ca5b1; color: #ffffff;"><center>What if plastic could cure people?</center></h1>
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<p class="resume" style="text-indent:3em; background-color: #f0f5f8;"> Today, scientists are looking for new ways to synthesize drugs. As one of the major pollutants, <b>plastic waste</b> is a growing resource with 25 million tons produced in 2014, in Europe alone. Because of their composition, plastics have a very slow degradation rate and produce persistent organic pollutants. This leads to an increase of plastic pollution and an accumulation of plastic <b>microparticles</b> in our ecosystem, especially in the oceans. <b>PlastiCure</b> is a biological system designed in <i>E. coli</i> to degrade polyethylene terephthalate and use the degradation products to synthesize a commonly used antibiotic: <b>Erythromycin A</b>. For this, exogenous DNA sequences are integrated in <b>multiple operons</b> to express the biodegradation pathway (22kb) and the biosynthesis pathway (55kb). PlastiCure is a <b>very innovative project</b> to address an environmental issue, plastic pollution, by degrading plastic into a profitable transformation product and thus increase efforts in plastic recycling. <center><a href="#Menu"><img src="https://static.igem.org/mediawiki/2015/c/c0/Skip_noir_pasteurparis2015.png" /> </a></center></p>
  
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<p id="Menu"></p>
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           <a href="https://2015.igem.org/Team:Pasteur_Paris/Description"><div class="col-md-12 Item1" id="itemMenuElement" style="background-image: url(https://static.igem.org/mediawiki/2015/1/13/IGEM_Pasteur_Poisson-plastique.png);">
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                   Problems
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           </div></a>
 
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                   Solution
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                   SOLUTION
 
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                   Results
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                   RESULTS
 
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                   Parts
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                   PARTS
 
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           </div>
 
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                   Practice
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                   PRACTICES
 
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         </div></a>
 
<!-- Add here the items (just at the top of this comment)-->
 
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                 <!-- Several div of Items -->
 
                 <!-- Several div of Items -->
                 <div class="sleek desc_item" id="desc_item1">
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                 <div class="sleek desc_item" id="desc_item1" style="text-align: justify; padding: 10px;">
                     <!--Plastic pollution is one of the major issuea real problem. Every oceans are polluted by micro and macro plastic particules. Macroparticules aren’t that much a problem because they are big enough to be removed. However, microparticules are so small that they get eaten and they can enter the food chain. How can we remove something that we can’t see by eyes ? That’s where we step in ! -->
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                     Every year, the world’s plastic production increases. In 2013, 299 million tons of plastic were produced throughout the world. However, recovery and recycling remain insufficient, and millions of tons end up in landfills, contribution to plastic pollution.
 
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                 </div>
                 <div class="sleek desc_item" id="desc_item2">
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                     <!--PlastiCure is a biological system designed to degrade PET (which is one of the most common plastic) and use the degradation products to synthesize bio-active compounds : we aim to transform plastic waste into a profitable life-saving drug : erythromycin A;-->
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                     PlastiCure is a biological system designed to degrade PET, one of the most commonly used plastic, and use the degradation products to synthesize Erythromycin A.
 
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                     Description of the item 3 in construction.
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                     Here, you can find our Notebook, the results, and the modeling of our system.
 
                 </div>
 
                 </div>
                 <div class="sleek desc_item" id="desc_item4">
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                 <div class="sleek desc_item" id="desc_item4"  style="text-align: justify; padding: 5px;">
                     <!--This is where you can see which Biobricks, chassis organism and cells we used during the iGEM competition. Moreover, there is detailed informations about every parts we used : their name, their natural function and how we used them in our project PlastiCure.-->
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                     This is where you can see which Biobricks, chassis organism and cells we used during the iGEM competition. There is detailed information about every part we used : their name, their natural function and how we used them in our project PlastiCure.
 
                 </div>
 
                 </div>
                 <div class="sleek desc_item" id="desc_item5">
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                     <!--During iGEM, we met a lot of people : scientists, journalists, politicians that helped us, talked to us and gave us tips. This chapter is where you’ll find every collaborations that we participated in, the mettings that we attended in during the summer and the philosophical work that we did on our project for the human practice.-->
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                     During iGEM, we met scientists, journalists, politicians that helped us and gave us tips. This chapter is where you’ll find every collaborations that we participated in, the mettings that we attended in during the summer.
 
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              <span style="font-size:1.5em; color:#999999;"> Grand Prize Winner <br/> Best Foundational Advance <br/> Best Poster Europe <br/> Advance to World Championship</span>
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                <span style="font-size:1.8em; color:#FCCA02;">Participating in the Foundational Advance track!</span><br/>
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Latest revision as of 02:05, 19 September 2015


What if plastic could cure people?

Today, scientists are looking for new ways to synthesize drugs. As one of the major pollutants, plastic waste is a growing resource with 25 million tons produced in 2014, in Europe alone. Because of their composition, plastics have a very slow degradation rate and produce persistent organic pollutants. This leads to an increase of plastic pollution and an accumulation of plastic microparticles in our ecosystem, especially in the oceans. PlastiCure is a biological system designed in E. coli to degrade polyethylene terephthalate and use the degradation products to synthesize a commonly used antibiotic: Erythromycin A. For this, exogenous DNA sequences are integrated in multiple operons to express the biodegradation pathway (22kb) and the biosynthesis pathway (55kb). PlastiCure is a very innovative project to address an environmental issue, plastic pollution, by degrading plastic into a profitable transformation product and thus increase efforts in plastic recycling.








Every year, the world’s plastic production increases. In 2013, 299 million tons of plastic were produced throughout the world. However, recovery and recycling remain insufficient, and millions of tons end up in landfills, contribution to plastic pollution.
PlastiCure is a biological system designed to degrade PET, one of the most commonly used plastic, and use the degradation products to synthesize Erythromycin A.
Here, you can find our Notebook, the results, and the modeling of our system.
This is where you can see which Biobricks, chassis organism and cells we used during the iGEM competition. There is detailed information about every part we used : their name, their natural function and how we used them in our project PlastiCure.
During iGEM, we met scientists, journalists, politicians that helped us and gave us tips. This chapter is where you’ll find every collaborations that we participated in, the mettings that we attended in during the summer.
Description in construction
Icons made by Freepik from www.flaticon.com is licensed by CC BY 3.0