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Revision as of 15:38, 21 August 2015
Welcome to Rose-Hulman's MitochONdriOFF project!
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Our project focuses on being able to control the cell's ability to use aerobic respiration for ATP production. We accomplish this is by creating a switch for the gene MRPS12 which encodes a protein that is necessary for mitochondrial ribosomal function. This stops the electron transport chain and forces the cell to ferment. Our chassis, S. cerevisae can survive purely through fermentation, which allows us to test this process without killing the cells.
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