Difference between revisions of "Team:RHIT"

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<p> On any page, click the power button in the header in order to see some extra effects</p>
 
<p> On any page, click the power button in the header in order to see some extra effects</p>
  
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<p> Our project focuses on controlling the expression of a mitochondrial ribosomal protein gene (<i>MRPS12</i>). By creating a genetic switch that can repress or derepress <i>MRPS12</i>, we can affect whether yeast (<i>S. cerevisiae</i>) undergoes aerobic respiration or fermentation. MRPS12 is vital to mitochondrial ribosomal function, therefore when it is not expressed, the mitochondrial ribosomes cannot translate the proteins required for the electron transport chain. Following this line of progression, when MRPS12 is repressed, aerobic respiration does not occur and the cells are forced to ferment. </p>  
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<p> Our project focuses on controlling the expression of a mitochondrial ribosomal protein gene (<i>MRPS12</i>). By creating a genetic switch that can repress or derepress <i>MRPS12</i>, we can affect whether yeast (<i>S. cerevisiae</i>) undergoes aerobic respiration or fermentation. MRPS12 is vital to mitochondrial ribosomal function, therefore when it is not expressed, the mitochondrial ribosomes cannot translate the proteins required for the electron transport chain. Following this line of progression, when <i>MRPS12</i> is repressed, aerobic respiration does not occur and the cells are forced to ferment. </p>  
  
  

Revision as of 14:56, 6 September 2015

Welcome to Rose-Hulman's MitochONdriOFF project!

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On any page, click the power button in the header in order to see some extra effects

Our project focuses on controlling the expression of a mitochondrial ribosomal protein gene (MRPS12). By creating a genetic switch that can repress or derepress MRPS12, we can affect whether yeast (S. cerevisiae) undergoes aerobic respiration or fermentation. MRPS12 is vital to mitochondrial ribosomal function, therefore when it is not expressed, the mitochondrial ribosomes cannot translate the proteins required for the electron transport chain. Following this line of progression, when MRPS12 is repressed, aerobic respiration does not occur and the cells are forced to ferment.

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