Difference between revisions of "Team:RHIT"

 
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<h1> Welcome to Rose-Hulman's Mitoch<span style="color:#DBA24C">ON</span>dri<span style="color:#9CFBE4">OFF</span> project!</h1>
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<h1 style="text-align:center"> Welcome to the RHIT Team's Mitoch<span style="color:#DBA24C">ON</span>dri<span style="color:#9CFBE4">OFF</span> project!</h1>
 
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<p> Throughout daily life, we come into contact with a number of products that are produced using yeast. Whether it be in brewing beer, baking bread, or creating medicines, yeast is an extremely common component to an industrial process. Part of what makes yeast so helpful is that it is able to survive using aerobic respiration and fermentation. This allows yeast to produce secondary metabolites, which we use in industrial processes.
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Our team focused specifically on working with S. cerevisiae which is common in both the brewing and baking processes (giving it the nickname ‘Baker’s yeast’. We worked to create a process that will allow the control of aerobic respiration, which will allow industry a little more freedom in manufacturing processes. Normally, fermentation will would occur until most of the carbon materials are gone, which includes sugars and other such materials. By being able to save these materials and still have fermentation, new tastes can be made. Furthermore, a common problem in industry is that the yeast will start to consume the product that the process is trying to make, since it is often carbon based. If the aerobic respiration is turned off however, the yeast will be unable to consume those materials </p>
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<p>Our project focuses on controlling aerobic respiration in the yeast <i>Saccharomyces cerevisiae</i>. We will address this objective by regulating the expression of mitochondrial ribosomal protein MRPS12. This protein is essential to the function of mitochondrial ribosomes, which produce key components of the electron transport chain. Without these components, the electron transport chain is disabled and aerobic respiration is not possible. </p>
  
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Latest revision as of 01:22, 19 September 2015

Welcome to the RHIT Team's MitochONdriOFF project!

Our project focuses on controlling aerobic respiration in the yeast Saccharomyces cerevisiae. We will address this objective by regulating the expression of mitochondrial ribosomal protein MRPS12. This protein is essential to the function of mitochondrial ribosomes, which produce key components of the electron transport chain. Without these components, the electron transport chain is disabled and aerobic respiration is not possible.