Difference between revisions of "Team:Warwick/Modelling1"

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<p><a href="https://2015.igem.org/Team:Warwick">Team Warwick</a> has shown interest in our offer to help in modeling and quantitative analysis that we have posted on the <a href="http://almaaslab.nt.ntnu.no/igem_matchmaker/">iGEM Matchmaker</a>. <a href="https://2015.igem.org/Team:Warwick">Team Warwick</a> is aiming to provide precision control over spatial arrangement of cells by designing a tool that enables drawing and building with them.</p>
 
<p><a href="https://2015.igem.org/Team:Warwick">Team Warwick</a> has shown interest in our offer to help in modeling and quantitative analysis that we have posted on the <a href="http://almaaslab.nt.ntnu.no/igem_matchmaker/">iGEM Matchmaker</a>. <a href="https://2015.igem.org/Team:Warwick">Team Warwick</a> is aiming to provide precision control over spatial arrangement of cells by designing a tool that enables drawing and building with them.</p>
  
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Zinc finger proteins are intracellular molecules which recognize and bind unique dsDNA sequences. We have engineered these proteins to be expressed on the surface of an E. coli cell, such that dsDNA can be used as mortar to cement cells together.  <a href="https://2015.igem.org/Team:Warwick">Team Warwick</a> plans to demonstrate this principle by assembling fluorescent cells onto a 2D surface and producing microscopic images, with the ultimate goal being to build complex 3D structures comprised of different cell types. This level of control over cellular localisation is useful in multiple fields including research into cell-cell interactions in microbial communities, multicellularity, and the construction of 3D cell structures in tissue engineering.</p>
  
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<p>The collaboration focused on two elements:
 
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<li>Calculating the <b>probability of formation</b>, including the probability of E. Coli bonding correctly.</p>
 
<li>Calculating the <b>probability of formation</b>, including the probability of E. Coli bonding correctly.</p>

Revision as of 21:24, 17 September 2015

Warwick iGEM 2015