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Click Chemistry

In figure 4 one can see three labelling RNAs each having different modifications respectively having either a C8 Alkyne-dUTP, 5-EdUTP or C8 Alkyne-dCTP incorporated. The Alexa 488 scan indicates that one Labelling RNA + 5-EdUTP was modified with an alkyne and that the CuAAC reaction was successful, too.

Figure 4: Enter here