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Revision as of 22:06, 27 August 2015
P4= Protein Products Pichia Plants
Our Project
Protein Products from Plants and Pichia: Novel Manufacturing of Analgesics and Cannabinoids
Cannabinoids and opiates are widely used classes of pharmaceuticals; unfortunately, these drugs have strong psychoactive effects or can be addictive. Our project consists of two ideas, both revolving around utilizing bioengineered microorganisms to create non-psychoactive cannabinoids and non-addictive analgesics. To achieve this we developed two projects: (1) Manufacturing a protein expression system to produce CBDA synthase in tobacco plants using agrobacterium, (2) Engineering the pGAPα vector system to express the mambalgin in Pichia Pastoris as a continuation of the 2014 GSU iGEM project. Simultaneously, we developed a proof of concept using horseradish peroxidase. By the end of this project we hope to have produced a synthetic biological system to manufacture pharmaceutical alternatives for patients that suffer from diseases such as epilepsy, cancer, or chronic severe pain.
Sponsor
![](https://static.igem.org/mediawiki/2015/b/ba/Idt_logo2015.jpg)
![](img/logos/03.png)
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Address
502, DieSachbearbeiter, Schönhauser Allee, 167c10435 Berlin,Germany.
Call Us
+40 (0) 012 345 6789
Get Connected With Us
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