Difference between revisions of "Team:NCTU Formosa/Overview"

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our hit product, is to display part of monoclonal antibody
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With our hit product, we provide the convenient and efficient diagnosis for prescribing personalized targeted drug therapy via tissue biopsies. To achieve this promising goal, the APOllO E.Cotector not only displays single chain variable fragment (scFv) which are directly from monoclonal antibody targeted drugs as probes to detect specific biomarkers, but also simultaneously expresses the florescent protein as signal for instant observation. Furthermore, by changing various kinds of scFv on the surfaces of E.Cotectors, it can identify multimarker and suggest physicians the prescription of combination and personalised therapy.</div>
targeted drugs, called scFv, outside the E.coli outer membrane
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and to express the fluorescent protein at the same time. It can
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stain the tissue biopsies by antibody-antigen interaction and
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perform fluorescence. Then it can help doctor determine the
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targeted drug therapy. Furthermore, by using various kinds of  
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APOllO E.Cotectors with different scFv and fluorescent
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proteins at the same time, we can identify multimarker to
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achieve combination therapy.</div>
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APOllO E.Cotector Plus is another powerful helper, which has not only displayed scFv but also Gold binding polypeptide, GBP, on the outer membrane of E.Coli. Our E.Cotector Plus can immobilize on gold, applied on any sensor used gold as transducer, to test the concentration of specific antigens in serum and to give more information about the patients' condition.
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To provide an alternative method of pre-diagnosis, APOllO E.Cotector Plus can not only display scFv but also able immobilize on gold surface. It can be applied on high-tech measurement machine which uses gold as signal transducer. Via the combination of various microbalances, APOllO E.Cotector Plus can truly determine the quantity of cancer antigens in serum. It can provide a cross comparison with tissue biopsies and provide doctors more details about cancer patients' condition.
 
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Revision as of 12:22, 2 September 2015

Team:NCTU Formosa/Overview - 2015.igem.org

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Team:NCTU Formosa/Overview

The overview of our E. Cotector and E. Cotector Plus
With our hit product, we provide the convenient and efficient diagnosis for prescribing personalized targeted drug therapy via tissue biopsies. To achieve this promising goal, the APOllO E.Cotector not only displays single chain variable fragment (scFv) which are directly from monoclonal antibody targeted drugs as probes to detect specific biomarkers, but also simultaneously expresses the florescent protein as signal for instant observation. Furthermore, by changing various kinds of scFv on the surfaces of E.Cotectors, it can identify multimarker and suggest physicians the prescription of combination and personalised therapy.
To provide an alternative method of pre-diagnosis, APOllO E.Cotector Plus can not only display scFv but also able immobilize on gold surface. It can be applied on high-tech measurement machine which uses gold as signal transducer. Via the combination of various microbalances, APOllO E.Cotector Plus can truly determine the quantity of cancer antigens in serum. It can provide a cross comparison with tissue biopsies and provide doctors more details about cancer patients' condition.
contact us
NCTU_Formosa APOllO   
  Engineering Building 6 EF455, 1001 University Road, Hsinchu 300, Taiwan, ROC.