Difference between revisions of "Team:NUDT CHINA/Practices"

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{{NUDT_CHINA}}
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<h2> Human Practices </h2>
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<!--NUDT_Container-->
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<style type="text/css">
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#NUDT_Container
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{
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clear: both;
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width: auto;
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margin: 30px 180px;
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padding: 30px 0px;
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font-family: 'verdana',sans-serif;
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#NUDT_Container table{
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{
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padding: 10px 50px;
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border: 0;
  
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<p>iGEM teams are unique and leading the field because they "go beyond the lab" to imagine their projects in a social/environmental context, to better understand issues that might influence the design and use of their technologies.</p>
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}
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<p>Teams work with students and advisors from the humanities and social sciences to explore topics concerning ethical, legal, social, economic, safety or security issues related to their work. Consideration of these Human Practices is crucial for building safe and sustainable projects that serve the public interest. </p>
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#NUDT_Container li
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<p>For more information, please see the <a href="https://2015.igem.org/Practices_Hub">Practices Hub</a>.</p>
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{
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padding: 0;
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border: 0;
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}
  
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<div class="highlightBox">
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#NUDT_Container p{
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<h4>Note</h4>
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text-decoration: none;
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<p>You must fill out this page in order to be considered for all <a href="https://2015.igem.org/Judging/Awards">awards</a> for Human Practices:</p>
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font-family: "Trebuchet MS", Helvetica, sans-serif;
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<ul>
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color: #888887;
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<li>Human Practices silver medal criterion</li>
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position: relative;
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<li>Human Practices gold medal criterion</li>
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padding: 10px 50px;
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<li>Best Integrated Human Practices award</li>
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font-size: 16px;
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<li>Best Education and Public Engagement award</li>
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}
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</ul>
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#NUDT_Container a {
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</div>
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position: relative;
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}
  
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#NUDT_Container a:hover
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{
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text-decoration:underline;
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}
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#NUDT_Container h1, h2, h3, h4, h5{
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color: #444;
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margin: 20px 0px;
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padding:4px 8px;
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letter-spacing: -1px;
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position: relative;
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}
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#NUDT_Container h1 {
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font:bold 28px/12px 'verdana',sans-serif;
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border-left: 10px solid #444;
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line-height:28px;
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}
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#NUDT_Container h2 {
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font:bold 20px/6px 'verdana',sans-serif;
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border-left: 30px solid #444;
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line-height:20px;
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}
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#NUDT_Container h3 {
 +
font:bold 16px/4px 'verdana',sans-serif;
 +
padding-left: 50px;
 +
line-height:16px;
 +
}
 +
/*CASE*/
 +
#NUDT_Container ca {
 +
position: relative;
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display: inline-block;
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margin: 10px 100px;
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    padding: 10px 20px;
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    text-decoration: none;
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background-color: #bcbcbc;
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color: #000000;
 +
border-radius: 8px 8px;
 +
outline: none;
 +
cursor: pointer;
 +
font-family: "Trebuchet MS", Helvetica, sans-serif;
 +
font-size: 16px;
 +
}
 +
</style>
 +
<!--DIA_Container-->
 +
<style type="text/css">
 +
#NUDT_Dia_Container
 +
{
 +
width: auto;
 +
margin: 0px 100px;
 +
}
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</style>
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<!--BLANK_Container-->
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<style type="text/css">
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.BLANK_Container
 +
{
 +
width: auto;
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}
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</style>
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<!--Common-->
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<div id = "myMainContainer">
 +
<div id = "bannerContainer">
 +
<img src="https://static.igem.org/mediawiki/2015/0/06/Team_NUDT_CHINA_banner.jpg" style="width: auto"/>
 +
</div>
 +
<div id = "menu">
 +
<img src="https://static.igem.org/mediawiki/2015/9/99/Menu.png"/>
 +
<li><a id = "HOME" href="https://2015.igem.org/Team:NUDT_CHINA"><span>HOME</span></a></li>
 +
 +
<li><a id = "PROJECT" href = "#"><span>PROJECT</span></a></li>
 +
<li><a id = "Description" href = "https://2015.igem.org/Team:NUDT_CHINA/Description" class = "b"><span>Description</span></a></li>
 +
<li><a id = "Experiments" href = "https://2015.igem.org/Team:NUDT_CHINA/Experiments" class = "b"><span>Experiments &amp; Protocols</span></a></li>
 +
<li><a id = "Results" href="https://2015.igem.org/Team:NUDT_CHINA/Results"  class = "b"><span>Results</span></a></li>
 +
<li><a id = "Design" href="https://2015.igem.org/Team:NUDT_CHINA/Design" class = "b"><span>Design</span></a></li>
 +
 +
<li><a id = "PARTS" href = "#"><span>PARTS</span></a></li>
 +
<li><a id = "Team" href = "https://2015.igem.org/Team:NUDT_CHINA/Parts" class = "b"><span>Team Parts</span></a></li>
 +
<li><a id = "Basic" href = "https://2015.igem.org/Team:NUDT_CHINA/Basic_Part" class = "b"><span>Basic Parts</span></a></li>
 +
<li><a id = "Composite" href="https://2015.igem.org/Team:NUDT_CHINA/Composite_Part"  class = "b"><span>Composite Parts</span></a></li>
  
−
<h5>Some Human Practices topic areas </h5>
 
−
<ul>
 
−
<li>Philosophy</li>
 
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<li>Public Engagement / Dialogue</li>
 
−
<li>Education</li>
 
−
<li>Product Design</li>
 
−
<li>Scale-Up and Deployment Issues</li>
 
−
<li>Environmental Impact</li>
 
−
<li>Ethics</li>
 
−
<li>Safety</li>
 
−
<li>Security</li>
 
−
<li>Public Policy</li>
 
−
<li>Law and Regulation</li>
 
−
<li>Risk Assessment</li>
 
−
</ul>
 
  
−
<h5>What should we write about on this page?</h5>
+
<li><a id = "NOTEBOOK" href="https://2015.igem.org/Team:NUDT_CHINA/Notebook"><span>NOTEBOOK</span></a></li> 
−
<p>On this page, you should write about the Human Practices topics you considered in your project, and document any special activities you did (such as visiting experts, talking to lawmakers, or doing public engagement).</p>
+
<li><a id = "ATTRIBUTIONS" href="https://2015.igem.org/Team:NUDT_CHINA/Attributions"><span>ATTRIBUTIONS</span></a></li> 
 +
<li><a id = "COLLABORATIONS" href="https://2015.igem.org/Team:NUDT_CHINA/Collaborations"><span>COLLABORATIONS</span></a></li>
 +
<li><a id = "HUMAN" href="https://2015.igem.org/Team:NUDT_CHINA/Practices"><span>HUMAN PRACTICES</span></a></li> 
 +
<li><a id = "SAFETY" href="https://2015.igem.org/Team:NUDT_CHINA/Safety"><span>SAFETY</span></a></li>
 +
<li><a id = "MODELING" href="https://2015.igem.org/Team:NUDT_CHINA/Modeling"><span>MODELING</span></a></li> 
 +
<li><a id = "MEASUREMENT" href="https://2015.igem.org/Team:NUDT_CHINA/Measurement"><span>MEASUREMENT</span></a></li> 
 +
<li><a id = "ENTREPRENEURSHIP" href="https://2015.igem.org/Team:NUDT_CHINA/Entrepreneurship"><span>ENTREPRENEURSHIP</span></a></li>
 +
    </div>
 +
    <div id = "logoContainer">
 +
    <a href="https://igem.org/Main_Page"><img  id = "iGEM_LOGO" src="https://static.igem.org/mediawiki/2015/e/ec/TEAM_NUDT_CHINA_iGEM_Logo.png" style="width: 130px; height:135px"/></a>
 +
    </div>
 +
<link href="https://2015.igem.org/Team:NEFU_China/cleariGEM.css?action=raw&ctype=text/css" rel="stylesheet" /> </head>
 +
</html>
 +
<html>
 +
<body>
 +
<!--Main Container-->
 +
<div id = "NUDT_Container" class = "clearStyle">
 +
<p style = "font-size: 12px;">TIPS: Click <B style = "color: #000000">SUBTITLE</B> to fold or unfold the content.</p>
 +
<h1>HUMAN PRACTICES</h1>
 +
<h2 id = "pos1" >INTERVIEW: Human Laboratory Animal Center</h2>
 +
<div class = "BLANK_Container" id = "slide1">
 +
<h3>I.PREFACE</h3>
 +
<p>Considering our project may have an impact on the biopharmaceutical field to a certain extent, especially on the efficiency of the production of drug, we interviewed Hunan Laboratory Animal Center (HLAC) for some advice on safety and prospect. </p>
 +
<h3>II.PARTICIPANTS</h3>
 +
<center>
 +
<table>
 +
<tr>
 +
<td><img src="NUDT_CHIAN_HP1_2.jpg" style="width: 400px; height:300px"/></td>
 +
</tr>
 +
<tr>
 +
<td style = "font-size: 10px;">Interviewers and Interviewee</td>
 +
</tr>
 +
</table>
 +
<p></p>
 +
<table>
 +
<tr>
 +
<td><img src="NUDT_CHIAN_HP1_Jiang1.png" style="width: 120px; height:120px"/></td>
 +
<td><img src="NUDT_CHIAN_HP1_Zhu1.png" style="width: 120px; height:120px"/></td>
 +
<td><img src="NUDT_CHIAN_HP1_Fan1.png" style="width: 120px; height:120px"/></td>
 +
<td><img src="NUDT_CHIAN_HP1_Wang1.png" style="width: 120px; height:120px"/></td>
 +
</tr>
 +
<tr>
 +
<td style = "font-size: 10px;"><B>Doctor</B> Jiang</td>
 +
<td style = "font-size: 10px;"><B>Instructor</B> Lingyun Zhu</td>
 +
<td style = "font-size: 10px;"><B>Student</B> Dongyu Fan</td>
 +
<td style = "font-size: 10px;"><B>Student</B> Yizhong Wang</td>
 +
</tr>
 +
</table>
 +
</center>
 +
<h3>III.SPOT</h3>
 +
<center>
 +
<table>
 +
<tr>
 +
<td><img src="NUDT_CHIAN_HP1_1.jpg" style="width: 400px; height:230px"/></td>
 +
</tr>
 +
<tr>
 +
<td style = "font-size: 10px;">Human Laboratory Animal Center</td>
 +
</tr>
 +
</table>
 +
</center>
 +
<h3>IV.DIALOGUE</h3>
 +
        <div id = "NUDT_Dia_Container">
 +
        <!--左-->
 +
            <!--头像-->
 +
            <section style="border: 0px; margin: 0.2em 0px; box-sizing: border-box; padding: 0px;">
 +
                <section style="display: inline-block; width: 80px; vertical-align: top; box-sizing: border-box;" >
 +
                    <!--头像png-->
 +
                    <section style="width: 60px; height: 60px; margin-left: 10px; border-top-left-radius: 60px; border-top-right-radius: 60px; border-bottom-right-radius: 60px; border-bottom-left-radius: 60px; background-image: url(NUDT_CHIAN_HP1_Fan1.png); background-size: cover; box-sizing: border-box; background-position: 50% 50%; background-repeat: no-repeat no-repeat;" ></section>
 +
                    <!--头像text-->
 +
                    <section  style="font-size: 0.8em; font-family: inherit; text-align: center; text-decoration: inherit; color: inherit; box-sizing: border-box;"><section  style="box-sizing: border-box;">Dongyu Fan
 +
                    </section>
 +
                    </section>
 +
                </section>
 +
            <!--对话-->
 +
                <section style="display: inline-block; width: 75%; font-size: 87.5%; font-family: inherit; text-decoration: inherit; color: inherit; border-color: #ffe4c8; box-sizing: border-box;">
 +
                    <!--对话box-->
 +
                    <section style="display: inline-block; width: 85%; margin-top: 11px; padding: 16px; border-top-left-radius: 16px; border-top-right-radius: 16px; border-bottom-right-radius: 16px; border-bottom-left-radius: 16px; background-color: #ffe4c8; box-sizing: border-box;" >
 +
                        <!--对话text-->
 +
                        <section style="box-sizing: border-box;">Moring Dr. Jiang, thank you for accept our interview. We all know that, in recent years, bio-pharmaceutical security has been subject to the general interest. We've learned that the Experimental Animal Center are already passed the identification of United States AAALAC Certification Center on safety evaluation of drugs. So we hope we can gain an objective and comprehensive assessment of our project and are eager for valuable advice through this interview.</section>
 +
                    </section>
 +
                </section>
 +
            </section>
 +
 
 +
 
 +
        <!--左-->
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                    <section  style="font-size: 0.8em; font-family: inherit; text-align: center; text-decoration: inherit; color: inherit; box-sizing: border-box;"><section  style="box-sizing: border-box;">Lingyun Zhu
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                        <section style="box-sizing: border-box;">Moring Dr. Jiang! First of all, I would like to introduce our project. What we are actually doing is using synthetic biology to build a DNA support system. This system is in microorganisms so that we can increase efficiency of regionalization reaction through metabolic engineering of multi-enzymatic reaction.</section>
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                        <section style="box-sizing: border-box;">As far as I understand, metabolic engineering is similar with biochemical reactions.</section>
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                        <section  style="box-sizing: border-box;">Dr. Jiang</section>
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                        <section style="box-sizing: border-box;">Could you evaluate the safety of our reconstruction project of the microbial?</section>
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                        <section style="box-sizing: border-box;">Our security assessment is mainly for drugs, such as the safety of medicines produced by the bioactive enzymes, which means we need a specific bioactive substance such as enzymes to conduct the safety assessment. Your project is more like a methodology study which does not have direct relation to medicine, so I can only make a safety assessment of potential safety hazard instead of a detailed one.</section>
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                        <section  style="box-sizing: border-box;">Dr. Jiang</section>
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                        <section style="box-sizing: border-box;">What influence will be make to the cells if we change the signaling pathways of cell?</section>
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                        <section style="box-sizing: border-box;">The level of the cell modification plays an important role in drug safety. Generally speaking, lower modification level means less side effects. Modification of subcellular structure may cause the cell activity change. If it leads to an acceleration of cell metabolism, it may eventually make the cell cancerous or autophagy.</section>
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                        <section  style="box-sizing: border-box;">Dr. Jiang</section>
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                        <section style="box-sizing: border-box;">What kind of side effects?</section>
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                        <section style="box-sizing: border-box;">Increasing reaction rate may result an accumulation of intermediate products which cause side effects. However, your project will not only increase the reaction efficiency but also make the reaction ordered. This modification of reaction chain makes reaction under control. In other word, the type and output of productions can be controlled. Theoretically, the side effects can be minimized.</section>
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                        <section  style="box-sizing: border-box;">Dr. Jiang</section>
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<h5>Inspiration</h5>
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<p>Read what other teams have done:</p>
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<li><a href="https://2014.igem.org/Team:Dundee/policypractice/experts">2014 Dundee </a></li>
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<li><a href="https://2014.igem.org/Team:UC_Davis/Policy_Practices_Overview">2014 UC Davis </a></li>
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<li><a href="https://2013.igem.org/Team:Manchester/HumanPractices">2013 Manchester </a></li>
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<li><a href="https://2013.igem.org/Team:Cornell/outreach">2013 Cornell </a></li>
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                        <section style="box-sizing: border-box;">Finally, could you please make a prospection of our project?</section>
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<h3>Integrated Human Practices</h3>
 
  
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<p>Do you want to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Integrated Human Practices award</a>? Make it easy for the judges to find any wiki content that is relevant to this prize. Highlight this content with a header or separate section.</p>
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                        <section style="box-sizing: border-box;">I have engaged in drug safety assessment many years. I think what restricts the development of the pharmaceutical industry is the disorder of reaction. The disorder makes it difficult to get the identical ingredients in different production batch which cause worse side effects. Your project is supposed to order the reaction chain and decrease the impure component of drug. This can not only increase the reaction rate but also improve the quality of drugs. I believe it will have a positive influence on the development of the pharmaceutical industry. </section>
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Revision as of 12:51, 5 September 2015

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HUMAN PRACTICES

INTERVIEW: Human Laboratory Animal Center

I.PREFACE

Considering our project may have an impact on the biopharmaceutical field to a certain extent, especially on the efficiency of the production of drug, we interviewed Hunan Laboratory Animal Center (HLAC) for some advice on safety and prospect.

II.PARTICIPANTS

Interviewers and Interviewee

Doctor Jiang Instructor Lingyun Zhu Student Dongyu Fan Student Yizhong Wang

III.SPOT

Human Laboratory Animal Center

IV.DIALOGUE

Dongyu Fan
Moring Dr. Jiang, thank you for accept our interview. We all know that, in recent years, bio-pharmaceutical security has been subject to the general interest. We've learned that the Experimental Animal Center are already passed the identification of United States AAALAC Certification Center on safety evaluation of drugs. So we hope we can gain an objective and comprehensive assessment of our project and are eager for valuable advice through this interview.
Lingyun Zhu
Moring Dr. Jiang! First of all, I would like to introduce our project. What we are actually doing is using synthetic biology to build a DNA support system. This system is in microorganisms so that we can increase efficiency of regionalization reaction through metabolic engineering of multi-enzymatic reaction.
As far as I understand, metabolic engineering is similar with biochemical reactions.
Dr. Jiang
Dongyu Fan
Could you evaluate the safety of our reconstruction project of the microbial?
Our security assessment is mainly for drugs, such as the safety of medicines produced by the bioactive enzymes, which means we need a specific bioactive substance such as enzymes to conduct the safety assessment. Your project is more like a methodology study which does not have direct relation to medicine, so I can only make a safety assessment of potential safety hazard instead of a detailed one.
Dr. Jiang
Dongyu Fan
What influence will be make to the cells if we change the signaling pathways of cell?
The level of the cell modification plays an important role in drug safety. Generally speaking, lower modification level means less side effects. Modification of subcellular structure may cause the cell activity change. If it leads to an acceleration of cell metabolism, it may eventually make the cell cancerous or autophagy.
Dr. Jiang
Dongyu Fan
What kind of side effects?
Increasing reaction rate may result an accumulation of intermediate products which cause side effects. However, your project will not only increase the reaction efficiency but also make the reaction ordered. This modification of reaction chain makes reaction under control. In other word, the type and output of productions can be controlled. Theoretically, the side effects can be minimized.
Dr. Jiang
Dongyu Fan
Finally, could you please make a prospection of our project?
I have engaged in drug safety assessment many years. I think what restricts the development of the pharmaceutical industry is the disorder of reaction. The disorder makes it difficult to get the identical ingredients in different production batch which cause worse side effects. Your project is supposed to order the reaction chain and decrease the impure component of drug. This can not only increase the reaction rate but also improve the quality of drugs. I believe it will have a positive influence on the development of the pharmaceutical industry.
Dr. Jiang
Dongyu Fan
Thanks for your answer.