Difference between revisions of "Team:technion"
(21 intermediate revisions by the same user not shown) | |||
Line 11: | Line 11: | ||
position: fixed; | position: fixed; | ||
z-index: 999; | z-index: 999; | ||
− | |||
left: 0; | left: 0; | ||
− | top: | + | top: 18px; |
width: 100%; | width: 100%; | ||
margin: auto; | margin: auto; | ||
font-family: MV Boli; | font-family: MV Boli; | ||
− | font-size: 1. | + | font-size: 1.6em; |
background: rgba(0,0,0,0.8); | background: rgba(0,0,0,0.8); | ||
height: 44px; | height: 44px; | ||
Line 34: | Line 33: | ||
.main_buttons { | .main_buttons { | ||
width: 665px; | width: 665px; | ||
− | height: | + | height: 30px; |
margin: auto; | margin: auto; | ||
− | margin-top: | + | margin-top: 10px; |
} | } | ||
Line 61: | Line 60: | ||
.main_links a { | .main_links a { | ||
− | font-size: 0. | + | font-size: 0.7em; |
padding-right: 15px; | padding-right: 15px; | ||
padding-left: 15px; | padding-left: 15px; | ||
Line 114: | Line 113: | ||
#Team_Links a:hover { | #Team_Links a:hover { | ||
background: rgb(247, 213, 11); | background: rgb(247, 213, 11); | ||
+ | } | ||
+ | |||
+ | .content { | ||
+ | margin-top: 100px; | ||
} | } | ||
</style> | </style> | ||
Line 303: | Line 306: | ||
<script type="text/javascript" src="https://2015.igem.org/Template:Technion/Javascript? | <script type="text/javascript" src="https://2015.igem.org/Template:Technion/Javascript? | ||
action=raw&ctype=text/javascript"></script> | action=raw&ctype=text/javascript"></script> | ||
+ | |||
+ | <!-----------------------------------------------nav-bar-script----------------------------------------> | ||
+ | <script type="text/javascript"> | ||
+ | $(document).ready(function() { | ||
+ | /************************reset parameters*********************************/ | ||
+ | var p = $("#project").offset(); | ||
+ | $("#project_Links").css({"padding-left": (p.left-0)}); | ||
+ | |||
+ | p = $("#Lab_Notebook").offset(); | ||
+ | $("#Lab_Notebook_Links").css({"padding-left": (p.left-0)}); | ||
+ | |||
+ | p = $("#Human_Practices").offset(); | ||
+ | $("#Human_Practices_Links").css({"padding-left": (p.left-0)}); | ||
+ | |||
+ | p = $("#Judging_Criteria").offset(); | ||
+ | if (($(window).width())*1.5 >= screen.width) | ||
+ | { | ||
+ | $("#Judging_Criteria_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | else | ||
+ | { | ||
+ | p = $("#project").offset(); | ||
+ | $("#Judging_Criteria_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | |||
+ | p = $("#Team").offset(); | ||
+ | if (($(window).width())*1 >= screen.width) | ||
+ | { | ||
+ | $("#Team_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | else | ||
+ | { | ||
+ | p = $("#project").offset(); | ||
+ | $("#Team_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | /************************reset parameters-end*****************************/ | ||
+ | |||
+ | /************************reset parameters on resize***********************/ | ||
+ | $(window).resize(function() { | ||
+ | var p = $("#project").offset(); | ||
+ | $("#project_Links").css({"padding-left": (p.left-0)}); | ||
+ | |||
+ | p = $("#Lab_Notebook").offset(); | ||
+ | $("#Lab_Notebook_Links").css({"padding-left": (p.left-0)}); | ||
+ | |||
+ | p = $("#Human_Practices").offset(); | ||
+ | $("#Human_Practices_Links").css({"padding-left": (p.left-0)}); | ||
+ | |||
+ | p = $("#Judging_Criteria").offset(); | ||
+ | if (($(window).width())*1.3 >= screen.width) | ||
+ | { | ||
+ | $("#Judging_Criteria_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | else | ||
+ | { | ||
+ | p = $("#project").offset(); | ||
+ | $("#Judging_Criteria_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | |||
+ | p = $("#Team").offset(); | ||
+ | if (($(window).width())*1 >= screen.width) | ||
+ | { | ||
+ | $("#Team_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | else | ||
+ | { | ||
+ | p = $("#project").offset(); | ||
+ | $("#Team_Links").css({"padding-left": (p.left-0)}); | ||
+ | } | ||
+ | }); | ||
+ | /************************reset parameters on resize-end*******************/ | ||
+ | |||
+ | /************************on hover events for main buttons*****************/ | ||
+ | $("#project, #project_Links a").hover(function() { | ||
+ | $("#project_Links").css({"max-height": "50px"}); | ||
+ | }, | ||
+ | function() { | ||
+ | $("#project_Links").css({"max-height": "0px"}); | ||
+ | }); | ||
+ | |||
+ | $("#Lab_Notebook, #Lab_Notebook_Links a").hover(function() { | ||
+ | $("#Lab_Notebook_Links").css({"max-height": "50px"}); | ||
+ | }, | ||
+ | function() { | ||
+ | $("#Lab_Notebook_Links").css({"max-height": "0px"}); | ||
+ | }); | ||
+ | |||
+ | $("#Human_Practices, #Human_Practices_Links a").hover(function() { | ||
+ | $("#Human_Practices_Links").css({"max-height": "50px"}); | ||
+ | }, | ||
+ | function() { | ||
+ | $("#Human_Practices_Links").css({"max-height": "0px"}); | ||
+ | }); | ||
+ | |||
+ | $("#Judging_Criteria, #Judging_Criteria_Links a").hover(function() { | ||
+ | $("#Judging_Criteria_Links").css({"max-height": "50px"}); | ||
+ | }, | ||
+ | function() { | ||
+ | $("#Judging_Criteria_Links").css({"max-height": "0px"}); | ||
+ | }); | ||
+ | |||
+ | $("#Team, #Team_Links a").hover(function() { | ||
+ | $("#Team_Links").css({"max-height": "50px"}); | ||
+ | }, | ||
+ | function() { | ||
+ | $("#Team_Links").css({"max-height": "0px"}); | ||
+ | }); | ||
+ | /************************on hover events for main buttons-end*************/ | ||
+ | |||
+ | }); | ||
+ | </script> | ||
+ | <!-----------------------------------------------nav-bar-script-end------------------------------------> | ||
</body> | </body> | ||
</html> | </html> |
Latest revision as of 19:04, 10 September 2015
page title
Hair loss affects roughly 61 million people in the United States. More than 95% of hair thinning in men is attributed to male pattern baldness, or androgenetic alopecia. The hair loss product market is a multi-billion dollar market: in the United States alone, this market’s annual revenue is 7 billion dollars, with 3.5% annual growth rate from 2007 to 2012, yet a sufficient solution has yet to be made available. The trigger for androgenetic alopecia is believed to be dihydrotestosterone (DHT), a derivative of testosterone. This summer, we are engineering Bacillus Subtilis, a model organism for a bacterium found naturally on the scalp, to secrete 3α-hydroxysteroid dehydrogenase (3-α-HSD). This enzyme reduces DHT to a non-steroidically active compound, using NADPH and NADH as cofactors.
Our project consists of 3 main parts: 3-α-HSD secretion by the bacterium, engineered bacterium for NADPH overproduction, and a comb as a tool to create a user-friendly experience. By synchronizing these parts, we hope to be able to show convincing evidence of DHT breakdown, providing a promising platform for treatment of male pattern baldness!