Difference between revisions of "Team:technion"

 
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Line 11: Line 11:
 
position: fixed;
 
position: fixed;
 
         z-index: 999;
 
         z-index: 999;
−
/*top: 50;*/
 
 
left: 0;
 
left: 0;
−
         top: 20px;
+
         top: 18px;
 
width: 100%;
 
width: 100%;
 
margin: auto;
 
margin: auto;
 
font-family: MV Boli;
 
font-family: MV Boli;
−
font-size: 1.3em;
+
font-size: 1.6em;
 
background: rgba(0,0,0,0.8);
 
background: rgba(0,0,0,0.8);
 
height: 44px;
 
height: 44px;
Line 34: Line 33:
 
.main_buttons {
 
.main_buttons {
 
width: 665px;
 
width: 665px;
−
height: 36px;
+
height: 30px;
 
margin: auto;
 
margin: auto;
−
margin-top: 4px;
+
margin-top: 10px;
 
}
 
}
  
Line 61: Line 60:
  
 
.main_links a {
 
.main_links a {
−
font-size: 0.75em;
+
font-size: 0.7em;
 
padding-right: 15px;
 
padding-right: 15px;
 
padding-left: 15px;
 
padding-left: 15px;
Line 307: Line 306:
 
<script type="text/javascript" src="https://2015.igem.org/Template:Technion/Javascript?
 
<script type="text/javascript" src="https://2015.igem.org/Template:Technion/Javascript?
 
action=raw&ctype=text/javascript"></script>
 
action=raw&ctype=text/javascript"></script>
 +
 +
<!-----------------------------------------------nav-bar-script---------------------------------------->
 +
<script type="text/javascript">
 +
$(document).ready(function() {
 +
/************************reset parameters*********************************/
 +
var p = $("#project").offset();
 +
$("#project_Links").css({"padding-left": (p.left-0)});
 +
 +
p = $("#Lab_Notebook").offset();
 +
$("#Lab_Notebook_Links").css({"padding-left": (p.left-0)});
 +
 +
p = $("#Human_Practices").offset();
 +
$("#Human_Practices_Links").css({"padding-left": (p.left-0)});
 +
 +
p = $("#Judging_Criteria").offset();
 +
if (($(window).width())*1.5 >= screen.width)
 +
{
 +
$("#Judging_Criteria_Links").css({"padding-left": (p.left-0)});
 +
}
 +
else
 +
{
 +
p = $("#project").offset();
 +
$("#Judging_Criteria_Links").css({"padding-left": (p.left-0)});
 +
}
 +
 +
p = $("#Team").offset();
 +
if (($(window).width())*1 >= screen.width)
 +
{
 +
$("#Team_Links").css({"padding-left": (p.left-0)});
 +
}
 +
else
 +
{
 +
p = $("#project").offset();
 +
$("#Team_Links").css({"padding-left": (p.left-0)});
 +
}
 +
/************************reset parameters-end*****************************/
 +
 +
/************************reset parameters on resize***********************/
 +
$(window).resize(function() {
 +
var p = $("#project").offset();
 +
$("#project_Links").css({"padding-left": (p.left-0)});
 +
 +
p = $("#Lab_Notebook").offset();
 +
$("#Lab_Notebook_Links").css({"padding-left": (p.left-0)});
 +
 +
p = $("#Human_Practices").offset();
 +
$("#Human_Practices_Links").css({"padding-left": (p.left-0)});
 +
 +
p = $("#Judging_Criteria").offset();
 +
if (($(window).width())*1.3 >= screen.width)
 +
{
 +
$("#Judging_Criteria_Links").css({"padding-left": (p.left-0)});
 +
}
 +
else
 +
{
 +
p = $("#project").offset();
 +
$("#Judging_Criteria_Links").css({"padding-left": (p.left-0)});
 +
}
 +
 +
p = $("#Team").offset();
 +
if (($(window).width())*1 >= screen.width)
 +
{
 +
$("#Team_Links").css({"padding-left": (p.left-0)});
 +
}
 +
else
 +
{
 +
p = $("#project").offset();
 +
$("#Team_Links").css({"padding-left": (p.left-0)});
 +
}
 +
});
 +
/************************reset parameters on resize-end*******************/
 +
 +
/************************on hover events for main buttons*****************/
 +
$("#project, #project_Links a").hover(function() {
 +
$("#project_Links").css({"max-height": "50px"});
 +
},
 +
function() {
 +
$("#project_Links").css({"max-height": "0px"});
 +
});
 +
 +
$("#Lab_Notebook, #Lab_Notebook_Links a").hover(function() {
 +
$("#Lab_Notebook_Links").css({"max-height": "50px"});
 +
},
 +
function() {
 +
$("#Lab_Notebook_Links").css({"max-height": "0px"});
 +
});
 +
 +
$("#Human_Practices, #Human_Practices_Links a").hover(function() {
 +
$("#Human_Practices_Links").css({"max-height": "50px"});
 +
},
 +
function() {
 +
$("#Human_Practices_Links").css({"max-height": "0px"});
 +
});
 +
 +
$("#Judging_Criteria, #Judging_Criteria_Links a").hover(function() {
 +
$("#Judging_Criteria_Links").css({"max-height": "50px"});
 +
},
 +
function() {
 +
$("#Judging_Criteria_Links").css({"max-height": "0px"});
 +
});
 +
 +
$("#Team, #Team_Links a").hover(function() {
 +
$("#Team_Links").css({"max-height": "50px"});
 +
},
 +
function() {
 +
$("#Team_Links").css({"max-height": "0px"});
 +
});
 +
/************************on hover events for main buttons-end*************/
 +
 +
});
 +
</script>
 +
<!-----------------------------------------------nav-bar-script-end------------------------------------>
 
</body>
 
</body>
 
</html>
 
</html>

Latest revision as of 19:04, 10 September 2015

Team: Technion 2015

Project
Lab Notebook
Human Practices
Judging Criteria
Team

page title

Our team is developing a treatment for male pattern baldness.

Hair loss affects roughly 61 million people in the United States. More than 95% of hair thinning in men is attributed to male pattern baldness, or androgenetic alopecia. The hair loss product market is a multi-billion dollar market: in the United States alone, this market’s annual revenue is 7 billion dollars, with 3.5% annual growth rate from 2007 to 2012, yet a sufficient solution has yet to be made available. The trigger for androgenetic alopecia is believed to be dihydrotestosterone (DHT), a derivative of testosterone. This summer, we are engineering Bacillus Subtilis, a model organism for a bacterium found naturally on the scalp, to secrete 3α-hydroxysteroid dehydrogenase (3-α-HSD). This enzyme reduces DHT to a non-steroidically active compound, using NADPH and NADH as cofactors.

Our project consists of 3 main parts: 3-α-HSD secretion by the bacterium, engineered bacterium for NADPH overproduction, and a comb as a tool to create a user-friendly experience. By synchronizing these parts, we hope to be able to show convincing evidence of DHT breakdown, providing a promising platform for treatment of male pattern baldness!

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