Bio-brick plays a crucial role in the field of synthetic biology; hence the core of WEiGEM is bio-brick. We further developed WEiGEM2.0 based on the popular WEiGEM1.0. Through WeChat, we establish a strong connection among iGEMers, mobile phone, and personal computer. Suffered by the low-efficiency bio-brick searching engines, we came up with the idea of developing a newer, more unique and more efficient searching engine based on the large bio-brick database from iGEM website. We picked several important attributions such as functions, types, status, etc. and assembled them in one search page, allowing users to fill up whatever search box with pieces of information that they consider necessary. Therefore, we can not only search bio-bricks by their names,but also search them according to certain descriptions. Furthermore, users can choose the binding type of prefix and receive bio-brick information with genetic sequences including prefixes and suffixes. Through redesigned algorithm which fits our engine most, our search engine can respond more quickly and be used more conveniently than those previous searching tools. After attaining the bio-bricks they need, if users consider some bio-bricks important, they can mark them down and review them later for other purposes.

1)Multiple search choice and cross-match In addition to the common free search mode, we considered the demand of users, and developed various humanized functions. For instance, the function column in the searching page serves to find bio-bricks by keywords in their function and helps an iGEMer match the functions he needs with the bio-bricks that are yet unknown to him but can possibly actualize his goals. This will definitely motivate the researchers’ inspirations when their minds sparkle and need to find bio-bricks immediately, conveniently and accurately.

2)Auto addition of prefix and suffix
Considering the feedback from wet teams that they find it troublesome to use the original genetic sequences without prefix and suffix during analog piecing experiments with great need of bio-bricks’ sequences, our search engine has the ability to add prefix and suffix according to users’ demands and display them with different color from the usual sequences. With a choice box including various binding types, users can simply choose the type they need and let the program judges the gene order of corresponding bio-bricks. Finally, users can view the genetic sequences with colored prefixes and suffixes and copy these sequences in one click. This seemingly tiny feature actually helps cut down useless efforts in experiments.