Difference between revisions of "Team:Penn"

 
(290 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Penn}}
+
{{Team:Penn/CSS}}
 +
<html>
 +
<head>
 +
<!--<link rel="stylesheet" type="text/css" media="screen, projection" href="https://98c43ce680a0761e7c3ad3c1d7ae34f6de6db886.googledrive.com/host/0B9QyOqpKYA2gdGV2aGFRMWh4aXM/style.css" />-->
 +
<title>University of Pennsylvania iGEM</title>
 +
<link href='http://fonts.googleapis.com/css?family=Open+Sans' rel='stylesheet' type='text/css'>
 +
</div>
 +
</head>
  
<html xmlns="http://www.w3.org/1999/xhtml">
+
<style type="text/css">
<head>
+
@import url(http://fonts.googleapis.com/css?family=Oswald:300,400,700);
<title>BusinessToday | Style Demo</title>
+
@import url(http://fonts.googleapis.com/css?family=Source+Sans+Pro:200,300,400,600,700,900,200italic,300italic,400italic,600italic,700italic,900italic);
<meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1" />
+
 
<link rel="stylesheet" href="../layout/styles/layout.css" type="text/css" />
+
/* Override UGG site */
</head>
+
#main {width: 100%; padding:0;}
<body id="top">
+
.content-asset p {margin:0 auto;}
<div class="wrapper col1">
+
.breadcrumb {display:none;}
  <div id="header">
+
 
    <div id="logo">
+
/* Helpers */
      <h1><a href="#">BusinessToday</a></h1>
+
/**************************/
      <p><strong>Free Website Template</strong></p>
+
.margin-top-10 {padding-top:10px;}
    </div>
+
.margin-bot-10 {padding-bottom:10px;}
    <div id="newsletter">
+
 
      <p>Sign up to our newsletter for the latest news, updates and offers.</p>
+
/* Typography */
      <form action="#" method="post">
+
/**************************/
        <fieldset>
+
#parallax-world-of-ugg h1 {font-family:'Oswald', sans-serif; font-size:100px; font-weight:600; text-transform: uppercase; color:black; padding:10px; margin:0;}
          <legend>NewsLetter</legend>
+
#parallax-world-of-ugg h2 {font-family:'Oswald', sans-serif; font-size:70px; letter-spacing:10px; text-align:center; color:white; font-weight:400; text-transform:uppercase; z-index:10; opacity:.8;}
          <input type="text" value="Name&hellip;"  onfocus="this.value=(this.value=='Name&hellip;')? '' : this.value ;" />
+
#parallax-world-of-ugg h3 {font-family:'Oswald', sans-serif; font-size:14px; line-height:0; font-weight:400; letter-spacing:8px; text-transform: uppercase; color:black;}
          <input type="text" value="Email&hellip;"  onfocus="this.value=(this.value=='Email&hellip;')? '' : this.value ;" />
+
#parallax-world-of-ugg p {font-family:'Source Sans Pro', sans-serif; font-weight:400; font-size:18px; line-height:24px;}
          <input type="submit" name="news_go" id="news_go" value="Sign Up" />
+
.first-character {font-weight:400; float: left; font-size: 84px; line-height: 64px; padding-top: 4px; padding-right: 8px; padding-left: 3px; font-family: 'Source Sans Pro', sans-serif;}
        </fieldset>
+
 
      </form>
+
.sc {color: #3b8595;}
    </div>
+
.ny {color: #3d3c3a;}
    <br class="clear" />
+
.atw {color: #c48660;}
  </div>
+
 
 +
/* Section - Title */
 +
/**************************/
 +
#parallax-world-of-ugg .title {background: white; padding: 20px; margin:0 auto; text-align:center;}
 +
#parallax-world-of-ugg .title h1 {font-size:35px; letter-spacing:8px;}
 +
 
 +
/* Section - Block */
 +
/**************************/
 +
#parallax-world-of-ugg .block {background: white; padding: 60px; width:1200px; margin:0 auto; text-align:justify;}
 +
#parallax-world-of-ugg .block-gray {background: #f2f2f2;padding: 60px;}
 +
#parallax-world-of-ugg .section-overlay-mask {position: absolute; top: 0; left: 0; width: 100%; height: 100%; background-color: black; opacity: 0.70;}
 +
 
 +
/* Section - Block2 */
 +
/**************************/
 +
#parallax-world-of-ugg .block2 {background: white; padding: 60px; width:800px; margin:0 auto; text-align:justify;}
 +
#parallax-world-of-ugg .block2-gray {background: #f2f2f2;padding: 60px;}
 +
#parallax-world-of-ugg .section-overlay-mask {position: absolute; top: 0; left: 0; width: 100%; height: 100%; background-color: black; opacity: 0.70;}
 +
 
 +
/* Section - Parallax */
 +
/**************************/
 +
#parallax-world-of-ugg .parallax-one {padding-top: 200px; padding-bottom: 200px; overflow: hidden; position: relative; width: 100%; background-image: url(https://static.igem.org/mediawiki/2015/0/06/Bulb-in-the-sunset-light-hd-background.jpg); background-attachment: fixed; background-size: cover; -moz-background-size: cover; -webkit-background-size: cover; background-repeat: no-repeat; background-position: top center;}
 +
#parallax-world-of-ugg .parallax-two {padding-top: 200px; padding-bottom: 200px; overflow: hidden; position: relative; width: 100%; background-image: url(https://static.igem.org/mediawiki/2015/0/07/Light.jpg); background-attachment: fixed; background-size: cover; -moz-background-size: cover; -webkit-background-size: cover; background-repeat: no-repeat; background-position: center center;}
 +
#parallax-world-of-ugg .parallax-three {padding-top: 200px; padding-bottom: 200px; overflow: hidden; position: relative; width: 100%; background-image: url(https://static.igem.org/mediawiki/2015/d/df/Communciation.jpg); background-attachment: fixed; background-size: cover; -moz-background-size: cover; -webkit-background-size: cover; background-repeat: no-repeat; background-position: center center;}
 +
 
 +
/* Extras */
 +
/**************************/
 +
#parallax-world-of-ugg .line-break {border-bottom:1px solid black; width: 150px; margin:0 auto;}
 +
 
 +
/* Media Queries */
 +
/**************************/
 +
@media screen and (max-width: 959px) and (min-width: 768px) {
 +
  #parallax-world-of-ugg .block {padding: 40px; width:620px;}
 +
}
 +
@media screen and (max-width: 767px) {
 +
  #parallax-world-of-ugg .block {padding: 30px; width:420px;}
 +
  #parallax-world-of-ugg h2 {font-size:30px;}
 +
  #parallax-world-of-ugg .block {padding: 30px;}
 +
  #parallax-world-of-ugg .parallax-one, #parallax-world-of-ugg .parallax-two, #parallax-world-of-ugg .parallax-three {padding-top:100px; padding-bottom:100px;}
 +
}
 +
@media screen and (max-width: 479px) {
 +
  #parallax-world-of-ugg .block {padding: 30px 15px; width:290px;}
 +
}
 +
</style>
 +
 
 +
<div id="parallax-world-of-ugg">
 +
<div class="boxed">
 +
 
 +
<div><img src="https://static.igem.org/mediawiki/2015/d/d4/Pennigem_mainbanner_15_%281%29.png" width="100%" alt></div>
 +
 
 +
<section>  
 +
<div class="title">
 +
<h1>OUR PROJECT</h1>
 
</div>
 
</div>
<div class="wrapper col2">
+
</section>
  <div id="topbar">
+
 
    <div id="topnav">
+
<table align="center">
      <ul>
+
 
        <li><a href="../index.html">Home</a></li>
+
<tr>
        <li class="active"><a href="style-demo.html">Style Demo</a></li>
+
<td>
        <li><a href="full-width.html">Full Width</a></li>
+
<img src="https://static.igem.org/mediawiki/2015/9/9d/Photocoupler2015Penn.png" alt />
        <li><a href="#">DropDown</a>
+
</td>
          <ul>
+
 
            <li><a href="#">Link 1</a></li>
+
<td>
            <li><a href="#">Link 2</a></li>
+
<div class="block2">
            <li><a href="#">Link 3</a></li>
+
      <p> Communication between cells is instrumental in coordinating population-level activity. In a process known as "quorum sensing," bacteria both secrete and sense autoinducer signaling molecules to enable synchronization of group gene expression paradigms. The synthetic biology community has rapidly adopted these quorum signaling pathways for use in programmed circuitry. However, chemical signals must diffuse between sender and receiver cells, limiting such communication to a common environment. In electronics, when electrical signals must be transferred between two circuits operating at incompatible voltages, electrical engineers use optocouplers, components that transfer information between isolated circuits via light. The 2015 Penn iGEM team presents a biological analog of the optocoupler, a cell-to-cell communication system in which a "sender" cell generates light via bioluminesence and a "receiver" cell expresses photoreceptors to enable light-dependent physiological responses. We show that light elicits a response in light-sensitive receivers and illuminated potential applications for this alternative form of cell communication.</p>
          </ul>
+
        </li>
+
        <li class="last"><a href="#">A Long Link Text</a></li>
+
      </ul>
+
    </div>
+
    <div id="search">
+
      <form action="#" method="post">
+
        <fieldset>
+
          <legend>Site Search</legend>
+
          <input type="text" value="Search Our Website&hellip;"  onfocus="this.value=(this.value=='Search Our Website&hellip;')? '' : this.value ;" />
+
          <input type="submit" name="go" id="go" value="Search" />
+
        </fieldset>
+
      </form>
+
    </div>
+
    <br class="clear" />
+
  </div>
+
 
</div>
 
</div>
<div class="wrapper col3">
+
</td>
  <div id="breadcrumb">
+
</tr>
    <ul>
+
 
      <li class="first">You Are Here</li>
+
</table>
      <li>&#187;</li>
+
 
      <li><a href="#">Home</a></li>
+
 
      <li>&#187;</li>
+
 
      <li><a href="#">Grand Parent</a></li>
+
 
      <li>&#187;</li>
+
 
      <li><a href="#">Parent</a></li>
+
<section>  
      <li>&#187;</li>
+
<div class="title">
      <li class="current"><a href="#">Child</a></li>
+
<h1>BREAKDOWN</h1>
    </ul>
+
  </div>
+
 
</div>
 
</div>
<div class="wrapper col5">
+
</section>
  <div id="container">
+
 
    <div id="content">
+
<table align = "center">
      <h1>&lt;h1&gt; to &lt;h6&gt; - Headline Colour and Size Are All The Same</h1>
+
<tr>
      <img class="imgr" src="../images/demo/imgr.gif" alt="" width="125" height="125" />
+
<td width="33.33%"><a href="https://2015.igem.org/Team:Penn/Sender"><img id = "daicon" src="https://static.igem.org/mediawiki/2015/4/4b/Pennigem_sender_15.png" height="85%" width="85%"></a></td>
      <p>Aliquatjusto quisque nam consequat doloreet vest orna partur scetur portortis nam. Metadipiscing eget facilis elit sagittis felisi eger id justo maurisus convallicitur.</p>
+
<td width="33.33%"><a href="https://2015.igem.org/Team:Penn/Receiver"><img id = "daicon" src="https://static.igem.org/mediawiki/2015/c/c0/Pennigem_receiver_15.png" height="85%" width="85%"></a></td>
      <p>Dapiensociis <a href="#">temper donec auctortortis cumsan</a> et curabitur condis lorem loborttis leo. Ipsumcommodo libero nunc at in velis tincidunt pellentum tincidunt vel lorem.</p>
+
<td width="33.33%"><a href="https://2015.igem.org/Team:Penn/Communication"><img id = "daicon" src="https://static.igem.org/mediawiki/2015/f/fc/Pennigem_comm_15.png" height="85%" width="85%"></a></td>
      <img class="imgl" src="../images/demo/imgl.gif" alt="" width="125" height="125" />
+
</tr>
      <p>This is a W3C compliant free website template from <a href="http://www.os-templates.com/" title="Free Website Templates">OS Templates</a>. This template is distributed using a <a href="http://www.os-templates.com/template-terms">Website Template Licence</a>.</p>
+
</table>
      <p>You can use and modify the template for both personal and commercial use. You must keep all copyright information and credit links in the template and associated files. For more CSS templates visit <a href="http://www.os-templates.com/">Free Website Templates</a>.</p>
+
<br><br>
      <p>Portortornec condimenterdum eget consectetuer condis consequam pretium pellus sed mauris enim. Puruselit mauris nulla hendimentesque elit semper nam a sapien urna sempus.</p>
+
 
      <h2>Table(s)</h2>
+
 
      <table summary="Summary Here" cellpadding="0" cellspacing="0">
+
 
        <thead>
+
 
          <tr>
+
 
            <th>Header 1</th>
+
 
            <th>Header 2</th>
+
<section>  
            <th>Header 3</th>
+
<div class="title">
            <th>Header 4</th>
+
<h1>HUMAN PRACTICES</h1>
          </tr>
+
        </thead>
+
        <tbody>
+
          <tr class="light">
+
            <td>Value 1</td>
+
            <td>Value 2</td>
+
            <td>Value 3</td>
+
            <td>Value 4</td>
+
          </tr>
+
          <tr class="dark">
+
            <td>Value 5</td>
+
            <td>Value 6</td>
+
            <td>Value 7</td>
+
            <td>Value 8</td>
+
          </tr>
+
          <tr class="light">
+
            <td>Value 9</td>
+
            <td>Value 10</td>
+
            <td>Value 11</td>
+
            <td>Value 12</td>
+
          </tr>
+
          <tr class="dark">
+
            <td>Value 13</td>
+
            <td>Value 14</td>
+
            <td>Value 15</td>
+
            <td>Value 16</td>
+
          </tr>
+
        </tbody>
+
      </table>
+
      <div id="comments">
+
        <h2>Comments</h2>
+
        <ul class="commentlist">
+
          <li class="comment_odd">
+
            <div class="author"><img class="avatar" src="../images/demo/avatar.gif" width="32" height="32" alt="" /><span class="name"><a href="#">A Name</a></span> <span class="wrote">wrote:</span></div>
+
            <div class="submitdate"><a href="#">August 4, 2009 at 8:35 am</a></div>
+
            <p>This is an example of a comment made on a post. You can either edit the comment, delete the comment or reply to the comment. Use this as a place to respond to the post or to share what you are thinking.</p>
+
          </li>
+
          <li class="comment_even">
+
            <div class="author"><img class="avatar" src="../images/demo/avatar.gif" width="32" height="32" alt="" /><span class="name"><a href="#">A Name</a></span> <span class="wrote">wrote:</span></div>
+
            <div class="submitdate"><a href="#">August 4, 2009 at 8:35 am</a></div>
+
            <p>This is an example of a comment made on a post. You can either edit the comment, delete the comment or reply to the comment. Use this as a place to respond to the post or to share what you are thinking.</p>
+
          </li>
+
          <li class="comment_odd">
+
            <div class="author"><img class="avatar" src="../images/demo/avatar.gif" width="32" height="32" alt="" /><span class="name"><a href="#">A Name</a></span> <span class="wrote">wrote:</span></div>
+
            <div class="submitdate"><a href="#">August 4, 2009 at 8:35 am</a></div>
+
            <p>This is an example of a comment made on a post. You can either edit the comment, delete the comment or reply to the comment. Use this as a place to respond to the post or to share what you are thinking.</p>
+
          </li>
+
        </ul>
+
      </div>
+
      <h2>Write A Comment</h2>
+
      <div id="respond">
+
        <form action="#" method="post">
+
          <p>
+
            <input type="text" name="name" id="name" value="" size="22" />
+
            <label for="name"><small>Name (required)</small></label>
+
          </p>
+
          <p>
+
            <input type="text" name="email" id="email" value="" size="22" />
+
            <label for="email"><small>Mail (required)</small></label>
+
          </p>
+
          <p>
+
            <textarea name="comment" id="comment" cols="100%" rows="10"></textarea>
+
            <label for="comment" style="display:none;"><small>Comment (required)</small></label>
+
          </p>
+
          <p>
+
            <input name="submit" type="submit" id="submit" value="Submit Form" />
+
            &nbsp;
+
            <input name="reset" type="reset" id="reset" tabindex="5" value="Reset Form" />
+
          </p>
+
        </form>
+
      </div>
+
    </div>
+
    <div id="column">
+
      <div class="subnav">
+
        <h2>Secondary Navigation</h2>
+
        <ul>
+
          <li><a href="#">Navigation - Level 1</a></li>
+
          <li><a href="#">Navigation - Level 1</a>
+
            <ul>
+
              <li><a href="#">Navigation - Level 2</a></li>
+
              <li><a href="#">Navigation - Level 2</a></li>
+
            </ul>
+
          </li>
+
          <li><a href="#">Navigation - Level 1</a>
+
            <ul>
+
              <li><a href="#">Navigation - Level 2</a></li>
+
              <li><a href="#">Navigation - Level 2</a>
+
                <ul>
+
                  <li><a href="#">Navigation - Level 3</a></li>
+
                  <li><a href="#">Navigation - Level 3</a></li>
+
                </ul>
+
              </li>
+
            </ul>
+
          </li>
+
          <li><a href="#">Navigation - Level 1</a></li>
+
        </ul>
+
      </div>
+
      <div class="holder">
+
        <h2 class="title"><img src="../images/demo/60x60.gif" alt="" />Nullamlacus dui ipsum conseque loborttis</h2>
+
        <p>Nullamlacus dui ipsum conseque loborttis non euisque morbi penas dapibulum orna. Urnaultrices quis curabitur phasellentesque.</p>
+
        <p class="readmore"><a href="#">Continue Reading &raquo;</a></p>
+
      </div>
+
      <div id="featured">
+
        <ul>
+
          <li>
+
            <h2>Indonectetus facilis leonib</h2>
+
            <p class="imgholder"><img src="../images/demo/240x90.gif" alt="" /></p>
+
            <p>Nullamlacus dui ipsum conseque loborttis non euisque morbi penas dapibulum orna. Urnaultrices quis curabitur phasellentesque congue magnis vestibulum quismodo nulla et feugiat. Adipisciniapellentum leo ut consequam ris felit elit id nibh sociis malesuada.</p>
+
            <p class="readmore"><a href="#">Continue Reading &raquo;</a></p>
+
          </li>
+
        </ul>
+
      </div>
+
      <div class="holder">
+
        <h2>Lorem ipsum dolor</h2>
+
        <p>Nuncsed sed conseque a at quismodo tris mauristibus sed habiturpiscinia sed.</p>
+
        <ul>
+
          <li><a href="#">Lorem ipsum dolor sit</a></li>
+
          <li>Etiam vel sapien et</li>
+
          <li><a href="#">Etiam vel sapien et</a></li>
+
        </ul>
+
        <p>Nuncsed sed conseque a at quismodo tris mauristibus sed habiturpiscinia sed. Condimentumsantincidunt dui mattis magna intesque purus orci augue lor nibh.</p>
+
        <p class="readmore"><a href="#">Continue Reading &raquo;</a></p>
+
      </div>
+
    </div>
+
    <div class="clear"></div>
+
  </div>
+
 
</div>
 
</div>
<div class="wrapper col6">
+
</section>
  <div id="footer">
+
 
    <div id="login">
+
<table align="center">
      <h2>Client Login !</h2>
+
<tr>
      <p>Clients can Login to their accounts here.</p>
+
<td>
      <form action="#" method="post">
+
<a href="https://2015.igem.org/Team:Penn/Educational_Toolbox"><img src="https://static.igem.org/mediawiki/2015/c/c3/Whatwillstandasatransferfunctionfornow3.png"></a></td>
        <fieldset>
+
<td>
          <legend>Client Login</legend>
+
<div class="block2">
          <div class="fl_left">
+
       <p> Analagous to  our project goals, the Penn iGEM 2015 team has worked to further illuminate the parallels between genetic circuits and electrical circuits with the addition of the PennTunes Toolbox. Just as there is a distinct change in response when replacing an electric circuit component, the various genetic parts included in this toolbox clearly demonstrate the divergence in expression level due to a change in genetic part (promoter, RBS, etc). As an example, we have characterized one of the inverter strains in the toolbox that exhibits the relationship in the figure to the right.
            <input type="text" value="Enter email address&hellip;"  onfocus="this.value=(this.value=='Enter email address&hellip;')? '' : this.value ;" />
+
</p>
            <input type="password" value="Enter password&hellip;"  onfocus="this.value=(this.value=='Enter password&hellip;')? '' : this.value ;" />
+
 
          </div>
+
<p>Our aim is to increase the reach of synthetic biology by providing the tools and infrastructure that will make biotechnology more accessible in educational settings. Find out more about our vision of the future for synthetic biology and biotechnology tools by clicking on the graph! </p>
          <div class="fl_right">
+
            <input type="submit" name="login_go" id="login_go" value="&raquo;" />
+
          </div>
+
        </fieldset>
+
      </form>
+
      <p><a href="#">&raquo; Lost Your Password</a> | <a href="#">Create An Account &raquo;</a></p>
+
    </div>
+
    <div class="footbox">
+
      <h2>Lacus interdum</h2>
+
      <ul>
+
        <li><a href="#">Praesent et eros</a></li>
+
        <li><a href="#">Praesent et eros</a></li>
+
        <li><a href="#">Lorem ipsum dolor</a></li>
+
        <li><a href="#">Suspendisse in neque</a></li>
+
        <li class="last"><a href="#">Praesent et eros</a></li>
+
      </ul>
+
    </div>
+
    <div class="footbox">
+
       <h2>Lacus interdum</h2>
+
      <ul>
+
        <li><a href="#">Praesent et eros</a></li>
+
        <li><a href="#">Praesent et eros</a></li>
+
        <li><a href="#">Lorem ipsum dolor</a></li>
+
        <li><a href="#">Suspendisse in neque</a></li>
+
        <li class="last"><a href="#">Praesent et eros</a></li>
+
      </ul>
+
    </div>
+
    <div class="footbox">
+
      <h2>Lacus interdum</h2>
+
      <ul>
+
        <li><a href="#">Praesent et eros</a></li>
+
        <li><a href="#">Praesent et eros</a></li>
+
        <li><a href="#">Lorem ipsum dolor</a></li>
+
        <li><a href="#">Suspendisse in neque</a></li>
+
        <li class="last"><a href="#">Praesent et eros</a></li>
+
      </ul>
+
    </div>
+
    <br class="clear" />
+
  </div>
+
 
</div>
 
</div>
<div class="wrapper col7">
+
</td>
  <div id="copyright">
+
</tr>
    <p class="fl_left">Copyright &copy; 2014 - All Rights Reserved - <a href="#">Domain Name</a></p>
+
</table>
    <p class="fl_right">Template by <a target="_blank" href="http://www.os-templates.com/" title="Free Website Templates">OS Templates</a></p>
+
 
    <br class="clear" />
+
 
  </div>
+
 
 +
 
 +
 
 +
 
 +
<style type="text/css">
 +
body { margin: 0;}
 +
header {
 +
  padding: .5vw;
 +
  font-size: 0;
 +
  display: -ms-flexbox;
 +
  -ms-flex-wrap: wrap;
 +
  -ms-flex-direction: column;
 +
  -webkit-flex-flow: row wrap;
 +
  flex-flow: row wrap;
 +
  display: -webkit-box;
 +
  display: flex;
 +
}
 +
header div {
 +
  -webkit-box-flex: auto;
 +
  -ms-flex: auto;
 +
  flex: auto;
 +
  width: 200px;
 +
  margin: .5vw;
 +
}
 +
header div img {
 +
  width: 100%;
 +
  height: auto;
 +
}
 +
@media screen and (max-width: 400px) {
 +
  header div { margin: 0; }
 +
  header { padding: 0; }
 +
}
 +
</style>
 +
 
 +
<section>  
 +
<div class="title">
 +
<h1>Our Team</h1>
 
</div>
 
</div>
</body>
+
</section>
 +
 
 +
<header>
 +
<div><img src="https://static.igem.org/mediawiki/2015/4/48/NikitaFrontPage.png" alt></div>
 +
<div><img src="https://static.igem.org/mediawiki/2015/8/86/HannahFrontPage.png" alt></div>
 +
<div><img src="https://static.igem.org/mediawiki/2015/a/a7/JaneFrontPage.png" alt></div>
 +
<div><img src="https://static.igem.org/mediawiki/2015/1/16/ShriramFrontPage.png" alt></div>
 +
<div><img src="https://static.igem.org/mediawiki/2015/e/e5/KarolFrontPage.png" alt></div>
 +
  <!-- images placed inside block elements to deal with a Firefox rendering bug affecting  scaled flexbox images -->
 +
</header>
 +
 
 +
 
 +
</div>
 +
</div>
 +
 
 +
<div style = "background: url('https://static.igem.org/mediawiki/2015/e/e0/Footer.png'); position:inherit; height:250px; background-size: 100%; background-repeat: no-repeat; background-position:center top;">
 
</html>
 
</html>

Latest revision as of 19:40, 16 September 2015

University of Pennsylvania iGEM

OUR PROJECT

Communication between cells is instrumental in coordinating population-level activity. In a process known as "quorum sensing," bacteria both secrete and sense autoinducer signaling molecules to enable synchronization of group gene expression paradigms. The synthetic biology community has rapidly adopted these quorum signaling pathways for use in programmed circuitry. However, chemical signals must diffuse between sender and receiver cells, limiting such communication to a common environment. In electronics, when electrical signals must be transferred between two circuits operating at incompatible voltages, electrical engineers use optocouplers, components that transfer information between isolated circuits via light. The 2015 Penn iGEM team presents a biological analog of the optocoupler, a cell-to-cell communication system in which a "sender" cell generates light via bioluminesence and a "receiver" cell expresses photoreceptors to enable light-dependent physiological responses. We show that light elicits a response in light-sensitive receivers and illuminated potential applications for this alternative form of cell communication.

BREAKDOWN



HUMAN PRACTICES

Analagous to our project goals, the Penn iGEM 2015 team has worked to further illuminate the parallels between genetic circuits and electrical circuits with the addition of the PennTunes Toolbox. Just as there is a distinct change in response when replacing an electric circuit component, the various genetic parts included in this toolbox clearly demonstrate the divergence in expression level due to a change in genetic part (promoter, RBS, etc). As an example, we have characterized one of the inverter strains in the toolbox that exhibits the relationship in the figure to the right.

Our aim is to increase the reach of synthetic biology by providing the tools and infrastructure that will make biotechnology more accessible in educational settings. Find out more about our vision of the future for synthetic biology and biotechnology tools by clicking on the graph!

Our Team