Difference between revisions of "Team:Warwick/Modeling"

(Undo revision 290267 by Jakeswain (talk))
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<p style="float: left;"><a href="BindingAffinity"><img src="https://static.igem.org/mediawiki/2015/6/66/Warwickmodeling5.png" align="right" height="100px" width="100px" border="1px"></p> <h5>Binding Affinity Modelling</h5></a>  
 
<p style="float: left;"><a href="BindingAffinity"><img src="https://static.igem.org/mediawiki/2015/6/66/Warwickmodeling5.png" align="right" height="100px" width="100px" border="1px"></p> <h5>Binding Affinity Modelling</h5></a>  
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A big problem biologists have is the uncertainty of bonding of cells, especially in our design where zinc fingers need to bind to cells. Therefore it is important to come up with a model which can calculate the number of cell and zinc finger binding sites required for a given output. Here we discussed how the zinc fingers bind to the glass slides and the association and disassociation constants which are factors in the number of cell that fully bind.
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A big problem biologists encounter is the uncertainty of bonding especially in our design where zinc fingers bind to cells. Therefore it is important to come up with a model which can calculate the number of cell and zinc finger binding sites required for a given output. This page discusses this and shows a program designed to dictate concentrations for the biologists to use.
  
  

Revision as of 09:10, 17 September 2015

Warwick iGEM 2015

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