Difference between revisions of "Team:Warwick/BindingAffinity"
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We have found said differential equation and then analytically solved it. After substituting in empirical data from the experiments, it is impossible to solve the equations to find the binding and unbinding constants (association and disassociation constants). Instead, we used a computational method to find these constants. Put simply this involved trying all the possible combinations of the constants (to the first significant figure) to find which best matches the empirical data. These results tell the biologists which zinc fingers have the best binding ability.<br> | We have found said differential equation and then analytically solved it. After substituting in empirical data from the experiments, it is impossible to solve the equations to find the binding and unbinding constants (association and disassociation constants). Instead, we used a computational method to find these constants. Put simply this involved trying all the possible combinations of the constants (to the first significant figure) to find which best matches the empirical data. These results tell the biologists which zinc fingers have the best binding ability.<br> | ||
| − | Another piece of code then uses these new found values to find out how much reactant to use, the related expenses, and how long the reaction will take.<br> | + | <br>Another piece of code then uses these new found values to find out how much reactant to use, the related expenses, and how long the reaction will take.<br> |
We are currently working on a piece of code that will test the DNA sequence to see if they are viable options for our experiment. | We are currently working on a piece of code that will test the DNA sequence to see if they are viable options for our experiment. | ||
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| + | <video id="ModellingClip" src="https://static.igem.org/mediawiki/2015/4/48/Warwickmodellingvideo.mp4" controls></video> | ||
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<p><img src="https://static.igem.org/mediawiki/2015/3/37/Warwickmodeling10.png" align="left" height="500px" width="700px" border="1px"></p> | <p><img src="https://static.igem.org/mediawiki/2015/3/37/Warwickmodeling10.png" align="left" height="500px" width="700px" border="1px"></p> | ||
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</div> | </div> | ||
Revision as of 09:38, 17 September 2015
