Difference between revisions of "Team:Warwick/Modeling"
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A big problem biologists encounter is the uncertainty of bonding especially in our design where zinc fingers bind to their sites. Therefore it is important to come up with a model which can calculate the number of cell and zinc finger binding sites required for a given output. This page discusses this and shows a program designed to dictate concentrations for the biologists to use.<br><br> | A big problem biologists encounter is the uncertainty of bonding especially in our design where zinc fingers bind to their sites. Therefore it is important to come up with a model which can calculate the number of cell and zinc finger binding sites required for a given output. This page discusses this and shows a program designed to dictate concentrations for the biologists to use.<br><br> | ||
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<p><a href="Modelling4"><h5>DNA Beading Model</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/a/a0/WarwickBead_Drawing.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | <p><a href="Modelling4"><h5>DNA Beading Model</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/a/a0/WarwickBead_Drawing.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | ||
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<p><a href="Modelling2"><h5>DNA Origami Glue Modelling</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/7/74/WarwickE.coli_Bonded_to_Origami.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | <p><a href="Modelling2"><h5>DNA Origami Glue Modelling</h5><p style="float: left;"><img src="https://static.igem.org/mediawiki/2015/7/74/WarwickE.coli_Bonded_to_Origami.png" align="right" height="100px" width="100px" border="1px"></p></p> </a> | ||
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The previous model of using DNA as a glue could create 3D shapes but would need vast amounts of unique zinc fingers. This wasn't possible with our time frame so we cam up with a model which could create a 3D structure from the minimum amount of unique DNA using tetrahedrons as a base to build from. Cells would then be bound to the outside.<br> | The previous model of using DNA as a glue could create 3D shapes but would need vast amounts of unique zinc fingers. This wasn't possible with our time frame so we cam up with a model which could create a 3D structure from the minimum amount of unique DNA using tetrahedrons as a base to build from. Cells would then be bound to the outside.<br> | ||
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Revision as of 12:40, 17 September 2015
