Difference between revisions of "Team:Georgia State/CBDA synthase"
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<p class="lead" style="color: rgb(0, 0, 0);"><b>CBDA Synthase is also known was cannabidiolic-acid synthase. It does not activate cannabinoid receptors (CB1 and CB2) and it has shown promise in treating many diseases or conditions such as: seizures, cancer, anxiety, pain, and many others. Since the CBDA synthase is 83.9% similar to THCA synthase in its 544-amino acid overlap, the synthesis of CBDA synthase should be similar to THCA synthase <a href="http://www.febsletters.org/article/S0014-5793(07)00572-8/abstract">(Futoshi et.al, 2007)</a>. </b></p> | <p class="lead" style="color: rgb(0, 0, 0);"><b>CBDA Synthase is also known was cannabidiolic-acid synthase. It does not activate cannabinoid receptors (CB1 and CB2) and it has shown promise in treating many diseases or conditions such as: seizures, cancer, anxiety, pain, and many others. Since the CBDA synthase is 83.9% similar to THCA synthase in its 544-amino acid overlap, the synthesis of CBDA synthase should be similar to THCA synthase <a href="http://www.febsletters.org/article/S0014-5793(07)00572-8/abstract">(Futoshi et.al, 2007)</a>. </b></p> | ||
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+ | <section id="about" class="wow fadeIn ptb ptb-sm-80" style="background-color: white;" > | ||
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+ | <h3 class="h4" style="text-align: left;color: black;">Horseradish Peroxidase</h3> | ||
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+ | <a class="cbox-gallary1 cboxElement" href="https://static.igem.org/mediawiki/2015/e/e4/HRP_GSUiGEM.JPG" title="Horseradish Peroxidase"> | ||
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+ | <img src="https://static.igem.org/mediawiki/2015/e/e4/HRP_GSUiGEM.JPG" style="float: right; height: 300px;"> | ||
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+ | <p class="lead" style="color: rgb(0, 0, 0);"><b>In an effort to show proof of concept for the CBDA synthase portion of the project, the GSU-iGem team is using horseradish peroxidase transformed into agrobacterium then producing transgenic tobacco plants. This part was designed in accordance to RFC 10.</b></p> | ||
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− | <p class="lead" style="color: rgb(0, 0, 0);"><b> | + | <p class="lead" style="color: rgb(0, 0, 0);"><b>pORE vector, agrobacter, plants. We will test this concept with the HRP part we designed. </b></p> |
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− | <p class="lead" style="color: rgb(0, 0, 0);"><b> | + | <p class="lead" style="color: rgb(0, 0, 0);"><b>Though sequencing has not been confirmed yet, we probably ligated the CBDA Synthase part into pSB1C3. We will continue work on this next year.</b></p> |
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Latest revision as of 01:01, 18 September 2015
CBDA Synthase
Construct Design
CBDA Synthase
CBDA Synthase is also known was cannabidiolic-acid synthase. It does not activate cannabinoid receptors (CB1 and CB2) and it has shown promise in treating many diseases or conditions such as: seizures, cancer, anxiety, pain, and many others. Since the CBDA synthase is 83.9% similar to THCA synthase in its 544-amino acid overlap, the synthesis of CBDA synthase should be similar to THCA synthase (Futoshi et.al, 2007).