Difference between revisions of "Team:SCUT-China/Practices"

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             <h3 style="color:#d53f60">Overview</h3>
 
             <h3 style="color:#d53f60">Overview</h3>
            <p>According to the data from WHO, cardiovascular diseases are the main leading cause of death globally. Cyclic guanosine monophosphate (cGMP) is a critical second messenger molecule.It can transduce nitric-oxide and natriuretic-peptide-coupled signaling and remit the myocardial hypertrophy by relaxing the blood vessels. This summer, we tried to use synthetic biology to modify the cGMP metabolic pathway in a human cell line. We hope that our work would provide the proof of principle for future gene therapy.</p>
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          <p>This year, our human practice has mainly focused on the topic “Public Engagement and Dialogue”.We have held a two-way dialogue between medical staff/patients and us to learn about present situation and advances in cardiovascular treatment. We have also interviewed the specialists in law to talk about current law and regulation about gene therapy in China. Additionally, we conducted a detailed data analyses of past iGEM projects and cardiovascular morbidity statistics. During the summer vacation, we spent time in having team seminars with other iGEM teams and presenting and promoting synthetic biology in the 6th China Cardiovascular Prevention and Rehabilitation Forum. Moreover, we used the “Wechat” public internet platform to send cardiovascular diseases prevention tips and the knowledge of synthetic biology to educate the public to care about their cardiovascular health condition and learn about synthetic biology. All in all, what we made contributions to really exert impact on a wide variety of people in our surroundings.</p>
 
              
 
              
 
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            <h3 style="color:#d53f60">Beyond the Bench and Back to the Bench</h3>
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            <p>We have spared no efforts to connect our human practice with laboratory work. We tried to make our human practice run through the experiments. Firstly, we searched and read plenty of papers, reports and past iGEM projects and analyzed the data we gathered. Secondly, we interviewed the doctors about present cardiovascular treatment and asked for advice of project design. After that, we had the first team seminar to talk about talent training and attended an important conference to present our initial idea and got lots of helpful and instructive feedbacks. After improvement, we implemented experiments and gained preliminary results. And then we had a dialogue with doctors to show the results and had the second team seminar to discuss how we can connect the modeling with our experiment. With abundant suggestions, we polished our project design again and gained more positive results which made us excited. Next, we made great contributions to promote the idea of gene therapy based on synthetic biology to those who are concerned about our project. We tried our best to have a dialogue with patients and discover their real living condition, and we introduce our new method of synthetic biology to acquire their precious thoughts and suggestions. Finally, we went back to the bench to do the final project design. That is the connection between our human practice and laboratory.</p>
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Revision as of 13:31, 18 September 2015

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Human Practices

Overview

This year, our human practice has mainly focused on the topic “Public Engagement and Dialogue”.We have held a two-way dialogue between medical staff/patients and us to learn about present situation and advances in cardiovascular treatment. We have also interviewed the specialists in law to talk about current law and regulation about gene therapy in China. Additionally, we conducted a detailed data analyses of past iGEM projects and cardiovascular morbidity statistics. During the summer vacation, we spent time in having team seminars with other iGEM teams and presenting and promoting synthetic biology in the 6th China Cardiovascular Prevention and Rehabilitation Forum. Moreover, we used the “Wechat” public internet platform to send cardiovascular diseases prevention tips and the knowledge of synthetic biology to educate the public to care about their cardiovascular health condition and learn about synthetic biology. All in all, what we made contributions to really exert impact on a wide variety of people in our surroundings.

Beyond the Bench and Back to the Bench

We have spared no efforts to connect our human practice with laboratory work. We tried to make our human practice run through the experiments. Firstly, we searched and read plenty of papers, reports and past iGEM projects and analyzed the data we gathered. Secondly, we interviewed the doctors about present cardiovascular treatment and asked for advice of project design. After that, we had the first team seminar to talk about talent training and attended an important conference to present our initial idea and got lots of helpful and instructive feedbacks. After improvement, we implemented experiments and gained preliminary results. And then we had a dialogue with doctors to show the results and had the second team seminar to discuss how we can connect the modeling with our experiment. With abundant suggestions, we polished our project design again and gained more positive results which made us excited. Next, we made great contributions to promote the idea of gene therapy based on synthetic biology to those who are concerned about our project. We tried our best to have a dialogue with patients and discover their real living condition, and we introduce our new method of synthetic biology to acquire their precious thoughts and suggestions. Finally, we went back to the bench to do the final project design. That is the connection between our human practice and laboratory.