Difference between revisions of "Team:BNU-CHINA"

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<p style="color:white;">(why not BNU-China..)</p>
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<h4>Project Description</h4>
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<h5>Title:Sirens</h5>
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<p>Pests are seriously detrimental to crops. In order to prevent this detriment, diverse kinds of chemical pesticides were used in last decades. However, these pesticides pollute the environment and increase the pest resistance substantially. Such that, it is very important to develop environment-friendly biological pest control methods, which can specifically reduce the pest populations but do not endanger other higher animals.</p>
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<p>Our project intend to build a novel engineering bacteria, which will express organics to allure pests and synthesis specific toxalbumin to kill the pests after they devour it. Furthermore, the bacteria will initiate suicide to avoid the damage to environment. </p>
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<p>Our project concerns mainly on nematode first, regarding nematode to be the crucial pathogenic organism, which most common types are ''Meloidogyne incognita'', ''Bursaphelencus xylophilus'' and ''Cyst Nematode''.</p>
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<p>A series of terpene compounds were identified, including linalool and limonene, to be the chemo-attractants for most insects, as well as play a certain role on attracting soil nematodes. So we pick linalool and limonene as the candidates from the chemo-attractants bait pool. We intend to build new metabolic pathways synthesizing these two terpene compounds in E.coli by providing linalool synthase and limonene synthase, then validate its effects on nematodes.
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<p>Two kinds of proteins are toxic for nematodes. Bace16 is the serine proteinase producing by an intracellular obligate parasites in nematodes called Bacillus sp. B16. Bace16 will inhibit the growth of nematodes by hydrolyzing their collagen and corneum. MpL is an agglutinin derived from Macrolepiota procera. Feeding nematodes with E.coli expressing MpL will prevent them attain maturity. In our project we are knocking Bace16 and rMpL in E.coli respectively. After devoured by baited nematodes, the E.coli will activate the toxalbumin expressing system to kill them specifically.
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<p>After a sophisticated nematode trap system is built, we will continue and expand the development of the trap systems for other kinds of agricultural pest, aiming at building the bait and the toxalbumin database of various pests.</p>
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<!--
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<h4>Before you start: </h4>
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<p> Please read the following pages:</p>
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<ul>
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<li>  <a href="https://2015.igem.org/Requirements">Requirements page </a> </li>
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<li> <a href="https://2015.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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</ul>
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<div class="highlightBox">
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<h4> Styling your wiki </h4>
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
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</div>
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<h4> Editing your wiki </h4>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>
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<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:BNU-CHINA&action=edit"> Click here to edit this page! </a></p>
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<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>
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<h4>Templates </h4>
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<p> This year we have created templates for teams to use freely. More information on how to use and edit the templates can be found on the
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<a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation </a> page.</p>
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<h4>Tips</h4>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<ul>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2015.igem.org/Calendar_of_Events">iGEM 2015 calendar</a> </li>
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<li>Have lots of fun! </li>
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</ul>
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<h4>Inspiration</h4>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<ul>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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</ul>
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<h4> Uploading pictures and files </h4>
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<p> You can upload your pictures and files to the iGEM 2015 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<a href="https://2015.igem.org/Special:Upload">CLICK HERE TO UPLOAD FILES</a>
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{{BNU-CHINA/wrapper |9/91/BNU_CHINA-home-1|BNU-CHINA|Synthetic Intelligent Ranger <em>E. coli</em> for Nematodes. |14|background-image:linear-gradient(-180deg, #FFFFFF 0%, #FFFFFF 60%, #A88F7B 100%);|border:none;font-family: 'Computer Modern Serif', serif;box-shadow:none;background:none;text-align: center;font-size:36px;line-height:48px;font-weight:700;padding: 0 0 }}
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{{BNU-CHINA/wrapper |0/0b/BNU_CHINA-home-2|BACKGROUND|Plant - parasitic nematodes which are usually too tiny to catch sight of have caused serious losses to agricultural crops worldwide. Over 5000 species of 200 genus can parasitize various organs of manifold plants widely. According to incomplete statistics, the losses caused by pathogenic nematodes can reach $100 billion every year worldwide. |72|background-image:linear-gradient(-180deg, #A88F7B 0%, #291E16 50%, #291E16 100%);|url=/Team:BNU-CHINA/Project}}
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{{BNU-CHINA/wrapper |c/c8/BNU_CHINA-home-3|BAIT & KILLER|In our project, we designed three modules to attract and poison plant-parasitic nematodes. The <em>E.coli</em> would express attractant to allure nematodes when exposed to light, and  express toxin to kill them as a result of the promoter’s reverse in the dark.|38.5|url=/Team:BNU-CHINA/Module}}
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{{BNU-CHINA/wrapper |7/73/BNU_CHINA-home-4|DEVICE|We designed a device with engineering bacteria inside, which can be placed in soil to attract and kill nematodes. We took advantage of gas diffusion and nematodes’ movement analogue simulation to find the best position for the device to be placed in an assuming farmland. And a database is built to broaden the scope of our applications.|20|url=/Team:BNU-CHINA/Design}}
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{{BNU-CHINA/wrapper |b/b6/BNU_CHINA-home-5|POLICY & PRACTICE|According to our survey, the farmer had not realize the damage of nematodes and we gave some suggestions to them. We interviewed related experts, dropped in the countryside, analyzed the soil sample, communicated with other teams and did assistance.|58.5|url=/Team:BNU-CHINA/Practices}}
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Latest revision as of 16:24, 18 September 2015

Team:BNU-CHINA - 2015.igem.org