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<p>The iGEM competition is the birthplace to many innovative ideas aimed at improving processes in synthetic biology by working with Genetically Engineered Organisms (GEO). However, most projects involve a risk of <b>GEOs dissemination</b> outside the laboratory, which raises environmental issues. To prevent such a risk, we designed a biosafety system that would prevent or at least dramatically limit the chances of accidental GEO spreading.</p>
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<p>The system consists in both a <b>physical confinement</b> which still allows the GEO to carry out its main function, and a <b>temperature-based containment</b> which ensures the survival of the organism in a restricted temperature range. <i>Escherichia coli</i> was chosen to implement the temperature based system due to its wide use in the iGEM projects. Thus, our system dubbed <b>SafetE.coli</b> could provide the iGEM teams with a "safer" chassis which is less likely to contaminate the environment.</p>
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</html>[https://static.igem.org/mediawiki/2015/2/2b/IGEM_Paris-Saclay_2015_SafetE.Coli_Poster.pdf Poster of the project SafetE.Coli iGEM Paris-Saclay 2015]<html>
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<ul class="nav"><!--
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--><li><a href="https://2015.igem.org/Team:Paris_Saclay">Home</a></li><!--
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--><li><a href="https://2015.igem.org/Team:Paris_Saclay/2015Project">Projet</a></li><!--
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  --><li><a href="https://2015.igem.org/Team:Paris_Saclay/2015Team">Team</a></li><!--
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--><li><a href="https://2015.igem.org/Team:Paris_Saclay/2015Labwork">Labwork</a></li><!--
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                --><li><a href="Modeling">Modeling</a></li><!--
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                --><li><a href="Ethics">Ethics</a></li><!--               
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                --><li> <a href="https://2015.igem.org/Team:Paris_Saclay/2015Interlab_Study">Interlab Study</a> </li>
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Latest revision as of 01:17, 19 September 2015

Abstract

The iGEM competition is the birthplace to many innovative ideas aimed at improving processes in synthetic biology by working with Genetically Engineered Organisms (GEO). However, most projects involve a risk of GEOs dissemination outside the laboratory, which raises environmental issues. To prevent such a risk, we designed a biosafety system that would prevent or at least dramatically limit the chances of accidental GEO spreading.

The system consists in both a physical confinement which still allows the GEO to carry out its main function, and a temperature-based containment which ensures the survival of the organism in a restricted temperature range. Escherichia coli was chosen to implement the temperature based system due to its wide use in the iGEM projects. Thus, our system dubbed SafetE.coli could provide the iGEM teams with a "safer" chassis which is less likely to contaminate the environment.

Poster of the project SafetE.Coli iGEM Paris-Saclay 2015
Contact
eigem.parissaclay AT gmail DOT com
t@iGEMParisSaclay
aUniversité Paris Sud
a91405 Orsay, France Copyright © 2015 iGEM Paris Saclay. All rights reserved All inspirations encouraged.
*This wiki was conceived during long nights of work and a great coffee experience in the beautiful Orsay, France.