Difference between revisions of "Team:Pasteur Paris/Modeling"

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<p>We have been decide to realise a modelisation of enzymatic kinectic. We have been think that interresting to study the successive evolution of differents substrates in the cell. We used the model of Michaelis-Menten as the basis of our model. We have solved this equation with the Euler-Cauchy method.</p>
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<p>We have decided to realize a model of enzyme kinetics. We thought that it would be interresting to study the successive evolution of differents substrates in the cell. We used the model of Michaelis-Menten as the basis of our model. We have solved this equation with the Euler-Cauchy method.</p>
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<p>The first goal of this part in our project was to realise a fitting curve fonctions, but we have finally developped a tool can give a solutions for many enzymatic systems respecting the Michaelis-Menten enzyme. This tool can be used as basis for create a fitting curve fonction. But it used as education tool for give a other approach of the enzymatic kinetic modelisation. </p>
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<p>The first goal of this part in our project was to realize a fitting curve fonction, but we have finally developped a tool that can generate solutions for many enzymatic systems respecting the Michaelis-Menten enzyme model. This tool can be used as a basis for creating a fitting curve function. But it can also be used as an education tool to provide another approach to the enzyme kinetic modeling. </p>
  
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<p>To built this tool, we rely on a spreadsheet : <a href="https://static.igem.org/mediawiki/2015/1/1a/MMtab.xls">Modeling tool forenzymatic reaction</a>  
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<p>To build this tool, we rely on a spreadsheet : <a href="https://static.igem.org/mediawiki/2015/1/1a/MMtab.xls">Modeling tool forenzymatic reaction</a>  
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<p>For the description of a equation used in the spreadsheet : <a href="https://static.igem.org/mediawiki/2015/d/d4/MM5-_Copie.pdf">Model to describe enzymatic reaction </a>
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<p>For the description of an equation used in the spreadsheet : <a href="https://static.igem.org/mediawiki/2015/d/d4/MM5-_Copie.pdf">Model to describe enzymatic reaction </a>
 
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Revision as of 01:30, 19 September 2015


We have decided to realize a model of enzyme kinetics. We thought that it would be interresting to study the successive evolution of differents substrates in the cell. We used the model of Michaelis-Menten as the basis of our model. We have solved this equation with the Euler-Cauchy method.

The first goal of this part in our project was to realize a fitting curve fonction, but we have finally developped a tool that can generate solutions for many enzymatic systems respecting the Michaelis-Menten enzyme model. This tool can be used as a basis for creating a fitting curve function. But it can also be used as an education tool to provide another approach to the enzyme kinetic modeling.

To build this tool, we rely on a spreadsheet : Modeling tool forenzymatic reaction

For the description of an equation used in the spreadsheet : Model to describe enzymatic reaction

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