Difference between revisions of "Team:Birkbeck"

 
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<H1>Media</H1>
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<H2>Vet Interviews</H2>
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<p>In the context of our project, a microscope would be useful for x, y z. </p>
 
<p>Bringing this cheap microscope technology to rural communities would also be extremely useful for practitioners working in the field, as described by these 4 vets: Dr Imran, Dr Muhammad Jawad Khan, Dr Anaheim and Dr Nabin Poran working in the field in Pakistan, Pakistan, Ethiopia and Nepal respectively. All these vets work on behalf of The Brooke, an international animal welfare organisation dedicated to improving the lives of working horses, donkeys and mules in some of the world's poorest communities. Please see their <a href="http://www.thebrooke.org/">website</a> for more details.</p>
 
 
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<H3>Dr Imran, Pakistan</H3>
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<center><video poster="https://static.igem.org/mediawiki/2015/9/9e/Owligos_Introduction_Presentation_Poster.png" id="projectintroduction" src="https://static.igem.org/mediawiki/2015/5/5a/Birkbeck_iGEM_2015_Project_Introduction.mp4" loop autoplay width="900px" height="675px"></video>
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<H1><b>Birkbeck iGEM</b></H1>
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<p>The <b>Owligos</b> are the <b>first-ever team</b> entered into the international Genetically Engineered Machine <b>(iGEM) Competition</b> by <b>Birkbeck, University of London</b>. We’re a <b>varied group of students who reflect the diversity and unique character of our institution:</b> many of us have chosen science as a second career, having already spent some time in full-time work. For most of us, this has meant making our way through a degree while continuing to work full-time. Hopefully this kind of dedication will help us successfully navigate our way through our iGEM project.</p>
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<H1><b>Project Aim</b></H1>
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<p><b>Our project aims to create a new diagnostic solution that will be low-tech and cost-effective enough to allow its usage in deprived and remote communities.</b> We’re attempting to <b>engineer a bacteriophage lambda </b>chassis to <b>change its host affinity</b>, while simultaneously<b> adding a marker</b> that will facilitate <b>easy detection</b> of a target <b>bacterial pathogen in patient samples</b>.</p>
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<p>To demonstrate this approach as a <b>proof of concept</b> for the competition, we plan to <b>change this affinity between different strains of <i>E.coli</i></b>; however, <b>ultimately</b> we hope to demonstrate that this principle could also be applied to alter the phage’s host range <b>to other bacterial species</b>. We could then <b>provide a modular system capable of diagnosing a range of diseases</b>. Of course, we haven’t chosen a simple goal. But as Birkbeck pioneers, we are determined to prove ourselves by making our project a success. We can’t wait to present the results of our work at the Giant Jamboree in September!</p>
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<H3>Dr Muhammad Jawad Khan, Pakistan</H3>
 
<video poster="https://static.igem.org/mediawiki/2015/6/64/IGEM2015_BBK_Florence.png" controls>
 
<source src="https://static.igem.org/mediawiki/2015/a/a2/Birkbeck_IMG_5726_compressed.mp4" type='video/mp4'/>
 
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<H3>Dr Anaheim, Ethiopia</H3>
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      <b>Link</b><br>
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<a href="https://2015.igem.org/Team:Birkbeck/Team"><img width="200px" height="auto" src="https://static.igem.org/mediawiki/2015/9/92/Shapoor.iGEM.BBK.2015.profile_picture.png" border="0"/></a>
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<br><br>
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<a href="https://2015.igem.org/Team:Birkbeck/Research"><img width="200px" height="auto" src="https://static.igem.org/mediawiki/2015/d/d7/Image_for_protocols_Button_iGEM2015_team_birkbeck.jpeg" border="0"/></a>
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<br><br>
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<a href="https://2015.igem.org/Team:Birkbeck/BioBricks"><img width="200px" height="auto" src="https://static.igem.org/mediawiki/2015/1/16/Birkbeck_ORF314_construct_w_BsaI_primers_before_%26_after.png" border="0"/></a>
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<br><br>
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<a href="https://2015.igem.org/Team:Birkbeck/Outreach"><img width="200px" height="auto" src="https://static.igem.org/mediawiki/2015/0/08/WP_20150624_15_53_58_Pro.jpg" border="0"/></a>
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<br><br>
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<a href="https://2015.igem.org/Team:Birkbeck/InterLab_Study"><img width="200px" height="auto" src="https://static.igem.org/mediawiki/2015/0/02/IGEM_2015_team_bbk_Phases_of_bacterial_growth_curve.jpg" border="0"/></a>
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<br><br>
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<a href="https://2015.igem.org/Team:Birkbeck/Notebook"><img width="200px" height="auto" src="https://static.igem.org/mediawiki/2015/7/7d/Birkbeck_phage_infection2.png" border="0"/></a>
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https://static.igem.org/mediawiki/2015/a/af/Birkbeck_phages2.png
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<!--<p>To find the background to our project</p>
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<p>To find out about protocols carried out in this project</p>
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<br><br><br><br><br><br><br><br>
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<p>To find measurements & statistical analysis</p>
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<br><br><br><br><br><br><br><br><br><br><br><br>
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<p>To find out more about our modeling</p>
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<br><br><br><br><br><br><br><br><br><br><br><br>
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<p>To find out more about our results</p>
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<br><br><br><br><br><br><br>
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<p>To find concluding remarks about our project</p>
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<br><br><br><br><br><br><br>
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<p>To find an overview of safety aspects of our project</p>
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  <td valign="top" rowspan="3" class="Summary">
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<!--<a class="twitter-timeline" href="https://twitter.com/BBKiGEM" data-widget-id="641370678273437698">Tweets by @BBKiGEM</a>
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<script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script>-->
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<p>Meet the team! From all participants in the first ever Birkbeck iGEM team to sponsors & people who have supported us throughout the project!</p>
 +
<br><br><br><br><br><br><br><br><br>
 +
<p>See exactly what we have been up to in the lab. Results, discussion, concluding remarks & safety aspects of our project are all in this section</p>
 +
<br><br><br><br><br><br><br><br><br><br><br><br>
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<p>See our biobrick collection.</p>
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<br><br><br><br><br><br>
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<p>See how we have out-reached to both the general community & iGEM community.</p>
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<br><br><br><br><br><br><br><br>
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<p>Consult our results from the interlab study with teams across the globe participating.</p>
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<br><br><br><br><br><br><br>
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<p>See what we have been up to on a weekly basis.</p>
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<!--<p>THANKYOU SEAN</p>
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<p>TEAM - This section of our website lets you know more about our team members and those outside the team, including our sponsors, without whom our project would never have been completed.</p>
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<p>RESEARCH - This section of our website lets you know important details about our project, like why did we choose it, what have we accomplished in the lab, and how have we ensured it is done safely.</p>
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<p>ETC.</p>-->
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<H1><b>Wiki Categories</b></H1>
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<p>Our wiki has six different categories, in addition to this main page. Some are divided into subcategories discussing similar topics, which are described below.</p>
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<H2><b><a href="https://2015.igem.org/Team:Birkbeck/Team">Team</a></b></H2>
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<p>Find out about each of our <b>team members, advisors and supervisors</b> by having a look at our <b><a href="https://2015.igem.org/Team:Birkbeck/Team">Team</a> page</b>.</p>
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<H2><b><a href="https://2015.igem.org/Team:Birkbeck/Research">Research</a></b></H2>
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<p>Find out about the <b>research we're conducting</b> by having a look at our <b><a href="https://2015.igem.org/Team:Birkbeck/Research">Research</a> page</b>, which <b>currently includes</b> an <b>overview of our <a href="https://2015.igem.org/Team:Birkbeck/Description">Project</a></b>, the <b>important <a href="https://2015.igem.org/Team:Birkbeck/pp">Background</a> to our research</b> and some of <b>our <a href="https://2015.igem.org/Team:Birkbeck/Experiments">Methods</a> used</b> to date.</p>
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<H2><b><a href="https://2015.igem.org/Team:Birkbeck/Modelling">Modelling</a></b></H2>
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<p>Page Under Construction</p>
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<H2><b><a href="https://2015.igem.org/Team:Birkbeck/Outreach">Outreach</a></b></H2>
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<p>Find out about our <b>outreach to society </b>by having a look at our <b><a href="https://2015.igem.org/Team:Birkbeck/Outreach">Outreach</a> page</b>, which <b>currently includes</b> our <b>voluntary work with the <a href="https://2015.igem.org/Team:Birkbeck/Practices">Community</a></b>.</p>
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<H2><b><a href="https://2015.igem.org/Team:Birkbeck/Cooperation">Cooperation</a></b></H2>
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<p>Find out about <b>help we have given and received</b> by having a look at our <b><a href="https://2015.igem.org/Team:Birkbeck/Cooperation">Cooperation</a> page</b>, which <b>currently includes</b> details of our <b><a href="https://2015.igem.org/Team:Birkbeck/Collaborations">Collaborations</a> with other iGEM teams</b> and <b><a href="https://2015.igem.org/Team:Birkbeck/Attributions/pp">Attributions</a></b> containing details of <b>our sponsors</b>.</p>
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<H2><b><a href="https://2015.igem.org/Team:Birkbeck/Notebook">Journal</a></b></H2>
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 +
<p>Find out what <b>progress we've made</b>, on a <b>weekly basis</b>, by having a look at our <b><a href="https://2015.igem.org/Team:Birkbeck/Notebook">Journal</a></b>.</p>
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<br>
 
<br>
  
<H3>Dr Nabin Poran, Nepal</H3>
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<img src="https://static.igem.org/mediawiki/2015/0/06/Birkbeck_campus.jpg" height=400 width=600>
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<source src="https://static.igem.org/mediawiki/2015/a/a2/Birkbeck_IMG_5734_compressed.mp4" type='video/mp4'/>
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<p>Where we live. We'll replace this with a picture of the team when we finally manage to get the whole group into a room together...</p>
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      <b>Become our sponsor:</b><br>
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<a href="http://www.gofundme.com/zq5h6s"><img src="https://static.igem.org/mediawiki/2015/7/74/Gfm_logo_300dpi.jpg" style="max-height:40px;"></a>
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<br> <br>
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  <b>Location:</b><br>
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  Birkbeck, University of London<br>
 +
  Malet Street<br>
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  London<br>
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  WC1E 7HX<br>
 
<br>
 
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<p style="font-style:italic;color:red;border-style:solid;border-width:2px;border-color:red">Your browser either does not support HTML5 or cannot handle MediaWiki open video formats. Please consider upgrading your browser, installing the appropriate plugin or switching to a Firefox or Chrome install.</p>
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  <b>Contact us:</b><br>
 +
  <a href="mailto:e.parris.11@alumni.ucl.ac.uk?subject=Mail from Owligos Website">
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  <a href="mailto:srcraig1987@hotmail.comk?subject=Mail from Owligos Website">
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    e.parris.11@alumni.ucl.ac.uk</a>
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<a href="http://www.bbk.ac.uk/"><img src="https://static.igem.org/mediawiki/2015/b/bc/BBK.2015.iGEM.Team.UniLogo.png" style="max-height:40px;"></a>
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<a href="http://www.ismb.lon.ac.uk/"><img src="https://static.igem.org/mediawiki/2015/a/a4/BBK.2015.iGEM.Team.ISMBLogo.png" style="max-height:40px;"></a>
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<a href="https://www.neb.com/"><img src="https://static.igem.org/mediawiki/2015/0/0b/NEB_SPONSOR_LOGO.png" style="max-height:40px;"></a>
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<br><br>
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<a href="http://www.snapgene.com/"><img src="https://static.igem.org/mediawiki/2015/a/ae/SNAPGENE_SPONSOR_LOGO.png" style="max-height:40px;"></a>
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<a href="http://www.idtdna.com/site"><img src="https://static.igem.org/mediawiki/2015/0/07/IDT_Logo_2015_%28corp_blue%29.jpg" style="max-height:40px;"></a>
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<a href="http://www.sbd.ee/"><img src="https://static.igem.org/mediawiki/2015/9/9e/Solis_biodyne-200.jpg" style="max-height:40px;"></a>
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<a href="http://www.genscript.com/"><img src="https://static.igem.org/mediawiki/2015/e/ee/Aalto-Helsinki_sponsorlogo_Genscript.gif" style="max-height:40px;"></a>
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<a href="http://store.biobasic.com/"><img src="https://static.igem.org/mediawiki/2015/d/d4/BBK_Team_2015_BBI_LOGO_JPEG.JPG" style="max-height:40px;"></a>
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<a href="http://www.bioline.com/uk/"><img src="https://static.igem.org/mediawiki/2015/a/a5/BIOLINE_SPONSOR_LOGO.png" style="max-height:40px;"></a>
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<br><br>
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<a href="http://www.engineering.ucl.ac.uk/"><img src="https://static.igem.org/mediawiki/2015/3/31/UCL_ENG_SPONSOR_LOGO.png" style="max-height:40px;"></a>
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<a href="http://www.thistlescientific.co.uk/"><img src="https://static.igem.org/mediawiki/2015/5/5d/IGEM_2015_Team_bbk_Thistle_Scientific.jpeg" style="max-height:40px;"></a>
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<a href="http://www.biospec.com/"><img src="https://static.igem.org/mediawiki/2015/9/92/IGEM_2015_team_BBK_BioSpec_Logo.jpg" style="max-height:40px;"></a>
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<a href="http://www.sens.org/"><img src="https://static.igem.org/mediawiki/2015/0/0e/SRF_Logo_Tall_LightBkgd-small.png" style="max-height:40px;"></a>
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<a href="http://www.longlifelabs.org/"><img src="https://static.igem.org/mediawiki/2015/3/37/Long_Life_Labs-small.jpg" style="max-height:40px;"></a>
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<a class="twitter-timeline" href="https://twitter.com/BBKiGEM" data-widget-id="641370678273437698">Tweets by @BBKiGEM</a>
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Latest revision as of 16:37, 16 October 2015

iGEM Westminster Logo




Birkbeck iGEM

The Owligos are the first-ever team entered into the international Genetically Engineered Machine (iGEM) Competition by Birkbeck, University of London. We’re a varied group of students who reflect the diversity and unique character of our institution: many of us have chosen science as a second career, having already spent some time in full-time work. For most of us, this has meant making our way through a degree while continuing to work full-time. Hopefully this kind of dedication will help us successfully navigate our way through our iGEM project.

Project Aim

Our project aims to create a new diagnostic solution that will be low-tech and cost-effective enough to allow its usage in deprived and remote communities. We’re attempting to engineer a bacteriophage lambda chassis to change its host affinity, while simultaneously adding a marker that will facilitate easy detection of a target bacterial pathogen in patient samples.

To demonstrate this approach as a proof of concept for the competition, we plan to change this affinity between different strains of E.coli; however, ultimately we hope to demonstrate that this principle could also be applied to alter the phage’s host range to other bacterial species. We could then provide a modular system capable of diagnosing a range of diseases. Of course, we haven’t chosen a simple goal. But as Birkbeck pioneers, we are determined to prove ourselves by making our project a success. We can’t wait to present the results of our work at the Giant Jamboree in September!