Difference between revisions of "Team:TrinityCollegeDublin"

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         One of the deadliest diseases in human history, <b>malaria</b> now claims over <u>600,000 lives a year</u>.  
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         One of the deadliest diseases in human history, <b>malaria now claims over 600,000 lives a year</b>.  
 
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Our mission is to investigate the production of affordable antimalarial drugs by the means of synthetic biology. We are working with <b>artemisinic acid producing E.coli cells</b> obtained from Amyris, with the support of Zagaya.  
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Our mission is to investigate the <b>production of affordable antimalarial drugs</b> by the means of synthetic biology. We are working with <b>artemisinic acid producing E.coli cells</b> obtained from Amyris, with the support of Zagaya.  
  
 
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We have constructed biobricks to take advantage of an alternative pathway in <u>artemesinin synthesis</u>. This pathway allows for the production of dihydroartemisinic acid, a direct precursor to artemisinin.  
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We have constructed biobricks to take advantage of an <b>alternative pathway in artemesinin synthesis</b>. This pathway allows for the production of <b>dihydroartemisinic acid</b>, a direct precursor to artemisinin.  
 
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This method has the potential for larger and cheaper artemisinin production in the future.
 
This method has the potential for larger and cheaper artemisinin production in the future.

Revision as of 15:02, 26 October 2015




E.artemisia

Combating Malaria with Synthetic Biology


One of the deadliest diseases in human history, malaria now claims over 600,000 lives a year.

Our mission is to investigate the production of affordable antimalarial drugs by the means of synthetic biology. We are working with artemisinic acid producing E.coli cells obtained from Amyris, with the support of Zagaya.


We have constructed biobricks to take advantage of an alternative pathway in artemesinin synthesis. This pathway allows for the production of dihydroartemisinic acid, a direct precursor to artemisinin.

This method has the potential for larger and cheaper artemisinin production in the future.