Difference between revisions of "Team:TCU Taiwan"

 
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     <td align="center"><span style="font-family:AR DESTINE,AR BONNIE,Comic Sans MS;"><font size="8"><font-weight: 900;>About Our Project</font></span></td>
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<span style="font-family:Levenim MT;"><font size="4">Our bacteria will going to express antimicrobial peptides to solve the rising problem of bacterial resistance. Our target is to develop it into a potential material of wound dressing. So we will test the peptides on Methicillin-Resistant Staphylococcus aureus to know it's ability to kill the Methicillin-Resistant Staphylococcus aureus. And we will always test these peptides in human cell culture using the HaCaT cell line and human fibroblasts cell to check it's ability to help wounds healing.</font>
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<span style="font-family:Calibri;"><font size="5">We are the TCU_Taiwan team representing Tzu-Chi University. This year, our team is comprised of twelve students from various departments and mentored by Professors Ji Hshiung Chen, Yung-Hao Ching and Guang-Huey Lin. </br></br>
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This year, we have endured many hardships to complete our project. In the face of adversity, as one team, we have confronted these challenges together. And in the process, we have grown stronger and developed into one large family. We enjoy the iGEM competition and look forward to sharing our achievements to the committee and the world.
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<font size="4">Our target is to develop antimicrobial peptides into a potential material of wound dressing. Our bacteria will express two kinds of antimicrobial peptides: Epinecidin-1 and Signiferin . Signiferin have the great ability to kill Methicillin-Resistant Staphylococcus aureus that had already proved by 2013 iGEM team:TU-Delft. Epinecidin-1 has the ability to help wounds healing. We let Ecoli to express them into culture medium and purified it to make wound dressing.</font></span>
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<span style="font-family:Calibri;"><font size="5">We are trying hard to complete our own job and also great effort to do the best. This year, we faced many challenges but we never gave up. We confronted these challenges together and discussed with our instructors. After overcoming lots of difficulties, we grew strong and became a big family. We are enjoying iGEM competition and looking forward to sharing our achievement to the world. </br></br>--></font>
 
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<span style="font-family:Calibri;"><font size="5">"Ouch! It hurts!" In this moment, a cut has penetrated our skin. As the wound appears on the skin, we became vulnerable to bacterial infection. Bacterial infections could slow down the wound recovery. In severe complications, if the infection is not properly treated, it could lead to severe consequences or even devastating amputation. Currently, antibiotics are the treatment standard to fight this complication. However due to extensive administration of antibiotics, drug-resistant bacteria have appeared, such as methicillin-resistant<I> Staphylocccus aureus</I> (MRSA). The problem of MRSA affects the world. In Taiwan, from 2005 to 2014, there are over 50% bacterial infection is cause by MRSA. Drug-resistant organisms pose significant problems in any patient treatment facility and impact our daily lives. Therefore, we want to test alternative antimicrobial agents for bacterial infection.</br></br></font></span>
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<span style="font-family:Calibri;"><font size="5">To ameliorate this problem, we can apply antimicrobial peptides (AMPs) during the wound healing process. We developing a medical dressing which can both inhibit MRSA infections and also facilitate would healing process. AMPs, are stable peptide that have extensive ability in bactericidal effects. Besides, the peptides also have ability to help skin recovered. The objective of this project is to apply AMPs to dressings to develop a potential anti-infective medical dressing. </font></span>
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Latest revision as of 13:57, 29 October 2015

About Our Team

We are the TCU_Taiwan team representing Tzu-Chi University. This year, our team is comprised of twelve students from various departments and mentored by Professors Ji Hshiung Chen, Yung-Hao Ching and Guang-Huey Lin.

This year, we have endured many hardships to complete our project. In the face of adversity, as one team, we have confronted these challenges together. And in the process, we have grown stronger and developed into one large family. We enjoy the iGEM competition and look forward to sharing our achievements to the committee and the world.



About Our Project

"Ouch! It hurts!" In this moment, a cut has penetrated our skin. As the wound appears on the skin, we became vulnerable to bacterial infection. Bacterial infections could slow down the wound recovery. In severe complications, if the infection is not properly treated, it could lead to severe consequences or even devastating amputation. Currently, antibiotics are the treatment standard to fight this complication. However due to extensive administration of antibiotics, drug-resistant bacteria have appeared, such as methicillin-resistant Staphylocccus aureus (MRSA). The problem of MRSA affects the world. In Taiwan, from 2005 to 2014, there are over 50% bacterial infection is cause by MRSA. Drug-resistant organisms pose significant problems in any patient treatment facility and impact our daily lives. Therefore, we want to test alternative antimicrobial agents for bacterial infection.

To ameliorate this problem, we can apply antimicrobial peptides (AMPs) during the wound healing process. We developing a medical dressing which can both inhibit MRSA infections and also facilitate would healing process. AMPs, are stable peptide that have extensive ability in bactericidal effects. Besides, the peptides also have ability to help skin recovered. The objective of this project is to apply AMPs to dressings to develop a potential anti-infective medical dressing.



             
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tcutaiwan@gmail.com
No.701, Sec. 3, Zhongyang Rd. Hualien 97004, Taiwan