Difference between revisions of "Team:Manchester-Graz"

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<h2> Welcome to iGEM 2015! </h2>
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<head>
<p>Your team has been approved and you are ready to start the iGEM season! </p>
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  <title>iGEM Manchester-Graz - Home</title>
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  <link href="design2.css" type="text/css" rel="stylesheet">
  
<h4>Before you start: </h4>
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</head>
<p> Please read the following pages:</p>
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<ul>
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<body>
<li>  <a href="https://2015.igem.org/Requirements">Requirements page </a> </li>
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<li> <a href="https://2015.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
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<!-- FACEBOOK SDK-->
</ul>
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<div class="highlightBox">
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    <script>
<h4> Styling your wiki </h4>
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      window.fbAsyncInit = function() {
<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
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        FB.init({
<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
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          appId      : 'your-app-id',
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          xfbml      : true,
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          version    : 'v2.3'
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        });
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      };
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      (function(d, s, id){
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        var js, fjs = d.getElementsByTagName(s)[0];
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        if (d.getElementById(id)) {return;}
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        js = d.createElement(s); js.id = id;
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        js.src = "//connect.facebook.net/en_US/sdk.js";
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        fjs.parentNode.insertBefore(js, fjs);
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      }(document, 'script', 'facebook-jssdk'));
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    </script>
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<div id="fb-root"></div>
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<script>(function(d, s, id) {
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  js.src = "//connect.facebook.net/en_GB/sdk.js#xfbml=1&amp;version=v2.3";
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  fjs.parentNode.insertBefore(js, fjs);
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}(document, 'script', 'facebook-jssdk'));</script>
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<img src="https://static.igem.org/mediawiki/2015/8/80/Manchester-Graz_Banner_big_obelix.jpg" alt="head_Webseite" width="960px" style="margin-left: 6px;">
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<div style="height: 50px;"> </div>
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<div class="buttonrow">
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<a class="buttonproject" href="https://2015.igem.org/Team:Manchester-Graz/Project"></a>
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<a class="buttonteam" href="https://2015.igem.org/Team:Manchester-Graz/Team"></a>
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<a class="buttonhp" href="https://2015.igem.org/Team:Manchester-Graz/Practices"></a>
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<a class="buttonmodeling" href="https://2015.igem.org/Team:Manchester-Graz/Modeling"></a>
 
</div>
 
</div>
  
<h4> Editing your wiki </h4>
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<div class="buttonrow">
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
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<a class="buttonparts" href="https://2015.igem.org/Team:Manchester-Graz/Parts"></a>
<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:Manchester-Graz&action=edit"> Click here to edit this page! </a></p>
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<a class="buttonnotebook" href="https://2015.igem.org/Team:Manchester-Graz/Notebook"></a>
<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>  
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<a class="buttoncollab"href="https://2015.igem.org/Team:Manchester-Graz/Collaborations"></a>
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<a class="buttonjudging" href="https://2015.igem.org/Team:Manchester-Graz/Judging"></a>
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</div>
  
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<div style="height: 25px;"> </div>
  
<h4>Templates </h4>
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<div id="inhalte_big">
<p> This year we have created templates for teams to use freely. More information on how to use and edit the templates can be found on the  
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<div id="why">
<a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation </a> page.</p>  
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<h3>Manchester-Graz: the first inter-European iGEM team</h3>
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<a href="https://static.igem.org/mediawiki/2015/d/dc/Manchester-Graz_Graz_nahe_kerstin_groß.jpg" target="_blank">
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<div id="pictureright" style="margin-left:10px;">
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<img src="https://static.igem.org/mediawiki/2015/c/c7/Manchester-Graz_Graz.jpg" alt="graz" width="400" height="267"><br> <center><b>Graz</b></center>
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</div></a>
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<p>Due to existing collaboration between the University of Manchester and the Graz University of technology in several research programs, such as CHEM21 and KYROBIO (European research projects), we came together as the first truly international cross-country iGEM team, supervised by professors Eriko Takano, Rainer Breitling and Sabine Flitsch in Manchester, and Anton Glieder in Graz. For the Austrian postgraduate subteam, this was a chance to enter the competition for the first time, with the support of the undergraduate students from Manchester, who could build on previous iGEM experience at their university. Once the joint team was formed, weekly Skype meetings were held to agree on a project, taking advantage of the collaboration to cover a wider area of research than would be possible as individual teams. We found working together as an international team challenging, and the distance required us to find a topic that could be worked on independently whilst still achieving a common goal. Overcoming this challenge, coupled with the exchange of knowledge and experience between the sub-teams, makes working on this project all the more rewarding.</p>
  
  
<h4>Tips</h4>
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<p>
<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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Our idea emerged from the different fields of interest of the students in Graz and Manchester, with the former wanting to generate a regulation system for protein synthesis, and the latter being more focused on medical aspects such as the synthesis of a drug. <a href="https://static.igem.org/mediawiki/2015/2/2c/Manchester-Graz_Manchester_big.jpg" target="_blank">
<ul>
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<div id="pictureleft" style="margin-bottom:10px; margin-right:15px;">
<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<img src="https://static.igem.org/mediawiki/2015/c/cf/Manchester-Graz_TeamManc.png" alt="Manchester" width="400" height="267"><br><center><b>Manchester</b></center>
<li>Be clear about what you are doing and how you plan to do this.</li>
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</div></a></p>
<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<p>The result was a quorum sensing based system for the autonomous production of L-DOPA and dopamine, with the students in Manchester working on the synthesis of L-DOPA and the students in Graz setting up an expression system that allows autonomous induction of several target genes. Using the advantage of two teams we can apply the L-DOPA pathway directly in a new system, which can already be evaluated in a real world context. <br><br>
<li>Make sure information is easy to find; nothing should be more than 3 clicks away. </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read. </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2015.igem.org/Calendar_of_Events">iGEM 2015 calendar</a> </li>
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<li>Have lots of fun! </li>
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There are also numerous advantages for our team outside the science. Public outreach and human practices (a particular area of interest) are more efficiently conducted across the two countries and yield more interesting data. Different attitudes towards synthetic biology and modern biotechnology can be determined on an international scale, in Austria and the United Kingdom respectively. In addition, the potential to gain valuable knowledge from interviews with experts in industry, medicine and patient care are greatly broadened as is the possibility for raising awareness about Parkinson’s and synthetic biology. <br><br>
</ul>  
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</p>
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<div id="video">
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<video width="700" style="margin-left:135px; margin-top:100px;" controls>
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  <source src="https://static.igem.org/mediawiki/2015/9/9d/Manchester-Graz_Labwork_%40_iGEM_Graz-Manchester.mp4" type="video/mp4">
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Your browser does not support the video tag.
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</video>
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</div>
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<div id="twitter">
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<div id="twitterbox">
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<a class="twitter-timeline" href="https://twitter.com/iGEMMancGraz" data-widget-id="619465263411499008" height="500" width="520" >Tweets by @iGEMMancGraz</a> <script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script>
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<div id="facebook">
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<div id="twitterbox">
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<!-- FACEBOOK thing 2 -->
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<div class="fb-page" data-href="https://www.facebook.com/iGEMManchesterGraz?fref=ts" style="margin-left:15px;" data-width="520" data-height="500" data-small-header="false" data-adapt-container-width="true" data-hide-cover="false" data-show-facepile="true" data-show-posts="true"><div class="fb-xfbml-parse-ignore"><blockquote cite="https://www.facebook.com/iGEMManchesterGraz?fref=ts"><a href="https://www.facebook.com/iGEMManchesterGraz?fref=ts">iGEM 2015 Manchester-Graz</a></blockquote></div></div>
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<div style="height: 50px;"> </div>
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<div id="sponsors" style="height:900px;">
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<div class="sponsorssmall">
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<a href="http://portal.tugraz.at/portal/page/portal/TU_Graz" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/0/06/Manchester-Graz_TU.jpg" alt="TU Graz" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.manchester.ac.uk" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/e/ed/Manchester-Graz_UniMan.jpg" alt="UniMan" width="200" height="100">
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</a>
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<div class="sponsorssmall">
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<a href="http://en.sanofi.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/7/77/Manchester-Graz_Sanofi.jpg" alt="Sanofi" width="200" height="100">
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</a>
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<div class="sponsorssmall">
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<a href="http://www.evolva.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/c/c6/Manchester-Graz_Evolva.jpg" alt="Evolva" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.bartelt.at" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/f/ff/Manchester-Graz_Bartelt.jpg" alt="bartelt" width="200" height="100">
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</a>
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<div class="sponsorssmall">
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<a href="https://eu.idtdna.com/site" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/d/d3/Manchester-Graz_IDT.jpg" alt="IDT" width="200" height="100">
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</a>
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<div class="sponsorssmall">
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<a href="http://www.lactan.at" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/7/7d/Manchester-Graz_Lactan.jpg" alt="Lactan" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.microsynth.at" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/a/ab/Manchester-Graz_Microsynth.jpg" alt="Microsynth" width="200" height="100">
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</a>
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<div class="sponsorssmall">
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<a href="https://www.qiagen.com/" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/7/77/Manchester-Graz_Qiagen.jpg" alt="Qiagen" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="https://www.neb.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/c/ca/Manchester-Graz_NEB.jpg" alt="NEB" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.thermofisher.com/en/home.html" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/c/cc/Manchester-Graz_ThermoFisher.jpg" alt="ThermoFisher" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="https://vwr.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/1/1a/Manchester-Graz_VWR.jpg" alt="VWR" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.ardeypharm.de" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/0/02/Manchester-Graz_Ardeypharm.jpg" alt="Ardeypharm" width="200" height="100">
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</a>
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<div class="sponsorssmall">
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<a href="http://www.snapgene.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/c/c7/Manchester-Graz_SnapGene.jpg" alt="Snapgene" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="https://www.sigmaaldrich.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/4/44/Manchester-Graz_Sigma.jpg" alt="Sigma-Aldrich" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://worldwide.promega.com/country.aspx?returnUrl=/" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/f/ff/Manchester-Graz_Promega.jpg" alt="Promega" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://smb.at" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/9/9d/Manchester-Graz_SMB.jpg" alt="Promega" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.merckmillipore.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/8/83/Manchester-Graz_Merck.jpg" alt="Promega" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://ibcarb.com" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/5/59/Manchester-Graz_Ibcarb.jpg" alt="Promega" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.kyrobio.eu" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/2/2c/Manchester-Graz_Kyrobio.jpeg" alt="Kyrobio" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall">
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<a href="http://www.chem21.eu" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/0/08/Chem21.jpg" alt="Kyrobio" width="200" height="100">
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</a>
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</div>
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<div class="sponsorssmall" style="border:none;">
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<a href="http://http://www.merck.com/index.html" target="_blank">
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<img src="https://static.igem.org/mediawiki/2015/9/91/Manchster-Graz_FacebookM.jpeg" alt="Merck" width="200" height="100">
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</div>
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<div class="sponsorssmall" style="border:none;">
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</div>
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<div class="sponsorssmall" style="margin-left:34px;">
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<img src="https://static.igem.org/mediawiki/2015/0/0f/Manchester-Graz_Sponsor_Thank_you.jpg" alt="Kyrobio" width="200" height="100">
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</div>
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</div>
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<div id="footer">
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<div id="footerlinks">
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<div class="footerheadline">
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Links
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</div>
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<div class="footerlinksbox">
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz" style="text-decoration:none;">Home</a><br>
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Project" style="text-decoration:none";>Project</a><br>
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Team" style="text-decoration:none";>Team</a><br>
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Practices" style="text-decoration:none">Human Practices</a><br>
 +
<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Modeling" style="text-decoration:none">Modeling</a><br>
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Parts" style="text-decoration:none">Parts</a><br>
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</div>
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<div class="footerlinksbox">
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Notebook" style="text-decoration:none">Notebook</a><br>
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<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Attributions" style="text-decoration:none">Attributions</a><br>
 +
<a class="footerlinks" href="https://2015.igem.org/Team:Manchester-Graz/Safety" style="text-decoration:none">Safety</a><br><br><br>
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<a class="footerlinks" href="https://2015.igem.org" style="text-decoration:none">iGEM</a>
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</div>
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</div>
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<div id="footercontact">
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<div class="footerheadline">
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Contact us
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</div>
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iGEM Subteam Graz<br>
 +
TU Graz, Institute of Molecular Biotechnology<br>
 +
Petersgasse 14<br>
 +
8010 Graz<br><br>
 +
 +
iGEM Subteam Manchester <br>
 +
University of Manchester<br>
 +
Manchester Institute of Biotechnology<br>
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131 Princess Street<br>
 +
Manchester M17DN
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</div>
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<div id="footerconnect">
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<div class="footerheadline">
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Connect
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</div>
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<a href="https://twitter.com/iGEMMancGraz"><img src="https://static.igem.org/mediawiki/2015/d/d0/Manchester-Graz_Twitter_64x262-03.png" alt="twitter_64x262-03" width="200" height="49"></a><br><br><br>
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<a href="https://www.facebook.com/pages/iGEM-Manchester-Graz/453856284768459"><img src="https://static.igem.org/mediawiki/2015/3/3e/Manchester-Graz_Facebook_64x262-03.png" alt="facebook_64x262-03" width="200" height="49"></a>
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</div>
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<div id="footerboringstuff">
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<div class="footerheadline">
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Boring Stuff
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</div>
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<br>
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<a class="footerboringstufflinks" href="https://2015.igem.org/Team:Manchester-Graz/Aboutus" style="text-decoration:none">About us</a><br>
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<a class="footerboringstufflinks" href="https://2015.igem.org/Team:Manchester-Graz/Legal" style="text-decoration:none">Legal Information</a>
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</div>
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<div id="footercopyright">
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&copy; iGEM Manchester-Graz
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</div>
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</div>
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<h4>Inspiration</h4>
 
<p> You can also view other team wikis for inspiration! Here are some examples:</p>
 
<ul>
 
<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
 
<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
 
<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
 
<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
 
<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
 
<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
 
</ul>
 
  
<h4> Uploading pictures and files </h4>
 
<p> You can upload your pictures and files to the iGEM 2015 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
 
When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
 
  
<a href="https://2015.igem.org/Special:Upload">CLICK HERE TO UPLOAD FILES</a>
 
  
  
  
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Latest revision as of 20:08, 17 November 2015

iGEM Manchester-Graz - Home

head_Webseite

Manchester-Graz: the first inter-European iGEM team

graz
Graz

Due to existing collaboration between the University of Manchester and the Graz University of technology in several research programs, such as CHEM21 and KYROBIO (European research projects), we came together as the first truly international cross-country iGEM team, supervised by professors Eriko Takano, Rainer Breitling and Sabine Flitsch in Manchester, and Anton Glieder in Graz. For the Austrian postgraduate subteam, this was a chance to enter the competition for the first time, with the support of the undergraduate students from Manchester, who could build on previous iGEM experience at their university. Once the joint team was formed, weekly Skype meetings were held to agree on a project, taking advantage of the collaboration to cover a wider area of research than would be possible as individual teams. We found working together as an international team challenging, and the distance required us to find a topic that could be worked on independently whilst still achieving a common goal. Overcoming this challenge, coupled with the exchange of knowledge and experience between the sub-teams, makes working on this project all the more rewarding.

Our idea emerged from the different fields of interest of the students in Graz and Manchester, with the former wanting to generate a regulation system for protein synthesis, and the latter being more focused on medical aspects such as the synthesis of a drug.

The result was a quorum sensing based system for the autonomous production of L-DOPA and dopamine, with the students in Manchester working on the synthesis of L-DOPA and the students in Graz setting up an expression system that allows autonomous induction of several target genes. Using the advantage of two teams we can apply the L-DOPA pathway directly in a new system, which can already be evaluated in a real world context.

There are also numerous advantages for our team outside the science. Public outreach and human practices (a particular area of interest) are more efficiently conducted across the two countries and yield more interesting data. Different attitudes towards synthetic biology and modern biotechnology can be determined on an international scale, in Austria and the United Kingdom respectively. In addition, the potential to gain valuable knowledge from interviews with experts in industry, medicine and patient care are greatly broadened as is the possibility for raising awareness about Parkinson’s and synthetic biology.