Difference between revisions of "Team:Technion Israel"

(Prototype team page)
 
Line 1: Line 1:
−
{{Technion_Israel}}
+
{{Template_All_Teams}}
−
<html>
+
<html>
−
<h2> Welcome to iGEM 2015! </h2>
+
<head>
−
<p>Your team has been approved and you are ready to start the iGEM season! </p>
+
<meta charset="utf-8"/>
 +
 +
<style type="text/css">
 +
 +
.abstract {
 +
font-size: 130%;
 +
}
 +
 +
.main_menu, footer {
 +
width: 650px;
 +
margin: auto;
 +
clear: both;
 +
}
 +
 +
#igem_login {
 +
float: right;
 +
color: white;
 +
background:#7f7f7f;
 +
background:rgba(0,0,0,0.2);
 +
}
 +
 +
#igem_login:hover {
 +
color: blue;
 +
}
 +
 +
#team_logo {
 +
width: 400px;
 +
height: auto;
 +
display: block;
 +
margin: auto;
 +
}
 +
 +
.facebook_link {
 +
margin-top: 5px;
 +
}
 +
 +
body {
 +
font-family: sans-serif;
 +
background-image: url("https://static.igem.org/mediawiki/2015/1/1b/Team_Technion_Background_Hair.jpg");
 +
}
 +
 +
.content {
 +
width: 700px;
 +
margin: auto;
 +
background:#7f7f7f;
 +
background:rgba(255,255,255,0.5);
 +
}
 +
 +
.abstract {
 +
position: relative;
 +
text-align: left;
 +
z-index: 1;
 +
margin-left: 10px;
 +
}
 +
 +
.abstract_title {
 +
position: relative;
 +
text-align: center;
 +
z-index: 1;
 +
}
 +
 +
 +
 +
/*************************footer****************/
 +
footer .team_name  {
 +
text-align: center;
 +
color: white;
 +
}
 +
 +
footer .connect_links {
 +
width: 130px;
 +
margin: auto;
 +
}
 +
 +
footer {
 +
background:#7f7f7f;
 +
background:rgba(0,0,0,0.5);
 +
width: 100%;
 +
}
 +
 +
footer h3 {
 +
margin-top: 0px;
 +
margin-bottom: 0px;
 +
}
 +
 +
.connect_links {
 +
display: flex;
 +
}
 +
/*************************footer-end*************/
 +
 +
 +
 +
 +
 +
/************************************************************************************/
 +
/***********************************Buttons******************************************/
 +
/************************************************************************************/
 +
 +
/*************************one****************/
 +
.button_main1 {
 +
background: #f33;
 +
color: #fff;
 +
border: 0;
 +
padding: 1em 2em;
 +
border-radius: 6px;
 +
cursor: pointer;
 +
border-bottom: 3px solid #e60000;
 +
outline: none;
 +
position: relative;
 +
overflow: hidden;
 +
}
 +
.button_main1:hover {
 +
border-bottom-width: 2px;
 +
margin-top: 0px;
 +
}
 +
.button_main1:active,
 +
.button_main1:focus {
 +
border-bottom-width: 1px;
 +
margin-top: 2px;
 +
-webkit-animation: shakeBtn 20ms infinite;
 +
animation: shakeBtn 20ms infinite;
 +
}
 +
.button_main1 .btn-text {
 +
position: relative;
 +
z-index: 1;
 +
}
 +
.button_main1 .btn-bg {
 +
position: absolute;
 +
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
 +
background: linear-gradient(to bottom, #f99, #ff1a1a);
 +
top: -100%;
 +
left: 0;
 +
width: 100%;
 +
height: 200%;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.button_main1:hover .btn-bg {
 +
top: 0;
 +
}
 +
/*************************one-end*************/
 +
/*************************two****************/
 +
.button_main2 {
 +
background: #f33;
 +
color: #fff;
 +
border: 0;
 +
padding: 1em 2em;
 +
border-radius: 6px;
 +
cursor: pointer;
 +
border-bottom: 3px solid #e60000;
 +
outline: none;
 +
position: relative;
 +
overflow: hidden;
 +
}
 +
.button_main2:hover {
 +
border-bottom-width: 2px;
 +
margin-top: 0px;
 +
}
 +
.button_main2:active,
 +
.button_main2:focus {
 +
border-bottom-width: 1px;
 +
margin-top: 2px;
 +
-webkit-animation: shakeBtn 20ms infinite;
 +
animation: shakeBtn 20ms infinite;
 +
}
 +
.button_main2 .btn-text {
 +
position: relative;
 +
z-index: 1;
 +
}
 +
.button_main2 .btn-bg {
 +
position: absolute;
 +
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
 +
background: linear-gradient(to bottom, #f99, #ff1a1a);
 +
top: -100%;
 +
left: 0;
 +
width: 100%;
 +
height: 200%;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.button_main2:hover .btn-bg {
 +
top: 0;
 +
}
 +
/*************************two-end*************/
 +
/*************************three****************/
 +
.button_main3 {
 +
background: #f33;
 +
color: #fff;
 +
border: 0;
 +
padding: 1em 2em;
 +
border-radius: 6px;
 +
cursor: pointer;
 +
border-bottom: 3px solid #e60000;
 +
outline: none;
 +
position: relative;
 +
overflow: hidden;
 +
}
 +
.button_main3:hover {
 +
border-bottom-width: 2px;
 +
margin-top: 0px;
 +
}
 +
.button_main3:active,
 +
.button_main3:focus {
 +
border-bottom-width: 1px;
 +
margin-top: 2px;
 +
-webkit-animation: shakeBtn 20ms infinite;
 +
animation: shakeBtn 20ms infinite;
 +
}
 +
.button_main3 .btn-text {
 +
position: relative;
 +
z-index: 1;
 +
}
 +
.button_main3 .btn-bg {
 +
position: absolute;
 +
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
 +
background: linear-gradient(to bottom, #f99, #ff1a1a);
 +
top: -100%;
 +
left: 0;
 +
width: 100%;
 +
height: 200%;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.button_main3:hover .btn-bg {
 +
top: 0;
 +
}
 +
/*************************three-end*************/
 +
/*************************four****************/
 +
.button_main4 {
 +
background: #f33;
 +
color: #fff;
 +
border: 0;
 +
padding: 1em 2em;
 +
border-radius: 6px;
 +
cursor: pointer;
 +
border-bottom: 3px solid #e60000;
 +
outline: none;
 +
position: relative;
 +
overflow: hidden;
 +
}
 +
.button_main4:hover {
 +
border-bottom-width: 2px;
 +
margin-top: 0px;
 +
}
 +
.button_main4:active,
 +
.button_main4:focus {
 +
border-bottom-width: 1px;
 +
margin-top: 2px;
 +
-webkit-animation: shakeBtn 20ms infinite;
 +
animation: shakeBtn 20ms infinite;
 +
}
 +
.button_main4 .btn-text {
 +
position: relative;
 +
z-index: 1;
 +
}
 +
.button_main4 .btn-bg {
 +
position: absolute;
 +
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
 +
background: linear-gradient(to bottom, #f99, #ff1a1a);
 +
top: -100%;
 +
left: 0;
 +
width: 100%;
 +
height: 200%;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.button_main4:hover .btn-bg {
 +
top: 0;
 +
}
 +
/*************************four-end*************/
 +
/*************************five****************/
 +
.button_main5 {
 +
background: #f33;
 +
color: #fff;
 +
border: 0;
 +
padding: 1em 2em;
 +
border-radius: 6px;
 +
cursor: pointer;
 +
border-bottom: 3px solid #e60000;
 +
outline: none;
 +
position: relative;
 +
overflow: hidden;
 +
}
 +
.button_main5:hover {
 +
border-bottom-width: 2px;
 +
margin-top: 0px;
 +
}
 +
.button_main5:active,
 +
.button_main5:focus {
 +
border-bottom-width: 1px;
 +
margin-top: 2px;
 +
-webkit-animation: shakeBtn 20ms infinite;
 +
animation: shakeBtn 20ms infinite;
 +
}
 +
.button_main5 .btn-text {
 +
position: relative;
 +
z-index: 1;
 +
}
 +
.button_main5 .btn-bg {
 +
position: absolute;
 +
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
 +
background: linear-gradient(to bottom, #f99, #ff1a1a);
 +
top: -100%;
 +
left: 0;
 +
width: 100%;
 +
height: 200%;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.button_main5:hover .btn-bg {
 +
top: 0;
 +
}
 +
/*************************five-end*************/
 +
 +
/************************************************************************************/
 +
/***********************************Buttons-end**************************************/
 +
/************************************************************************************/
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
 +
/************************************************************************************/
 +
/***********************************dropdown menu************************************/
 +
/************************************************************************************/
 +
 +
.dropdown {
 +
position: fixed;
 +
top: 10px;
 +
display: inline-block;
 +
float: left;
 +
z-index: 999;
 +
}
 +
.dropdown nav {
 +
max-height: 0px;
 +
overflow: hidden;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.dropdown nav a {
 +
display: block;
 +
}
 +
.dropdown:hover nav {
 +
max-height: 999px;
 +
}
 +
.dropdown a {
 +
width: 155px;
 +
display: inline-block;
 +
background: #33f;
 +
background:rgba(0,0,0,0.4);
 +
color: #fff;
 +
text-decoration: none;
 +
text-align: center;
 +
padding: 1em 2em;
 +
font-family: sans-serif;
 +
}
 +
 +
.dropdown a:hover {
 +
background: #33f;
 +
background:rgba(0,0,0,0.8);
 +
}
 +
/*************************one*****************************/
 +
.sub1 {
 +
overflow: hidden;
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
max-width: 0;
 +
max-height: 50px;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.sub1 a {
 +
background: #ffb733;
 +
background:rgba(255,183,51,0.4);
 +
}
 +
.main1 {
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
}
 +
 +
.main1 a {
 +
width: 140px;
 +
}
 +
 +
.main1:hover .sub1 {
 +
max-width: 999px;
 +
max-height: 50px;
 +
}
 +
.btn-bg1 {
 +
background: #ffb733;
 +
background:rgba(255,183,51,0.4);
 +
height: 50px;
 +
width: 14px;
 +
}
 +
 +
.sub1 a:hover {
 +
background: #ffb733;
 +
background:rgba(255,183,51,0.8);
 +
}
 +
/*************************one*****************************/
 +
/*************************two*****************************/
 +
.sub2 {
 +
overflow: hidden;
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
max-width: 0;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.sub2 a {
 +
background: #00a600;
 +
background:rgba(0,166,0,0.4);
 +
}
 +
.main2 {
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
}
 +
 +
.main2 a {
 +
width: 140px;
 +
}
 +
 +
.main2:hover .sub2 {
 +
max-width: 999px;
 +
max-height: 50px;
 +
}
 +
.btn-bg2 {
 +
background: #00a600;
 +
background:rgba(0,166,0,0.4);
 +
height: 50px;
 +
width: 14px;
 +
}
 +
 +
.sub2 a:hover {
 +
background: #ffb733;
 +
background:rgba(0,166,0,0.8);
 +
}
 +
/*************************two*****************************/
 +
/*************************three*****************************/
 +
.sub3 {
 +
overflow: hidden;
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
max-width: 0;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.sub3 a {
 +
background: #ff1a1a;
 +
background:rgba(255,26,26,0.4);
 +
}
 +
.main3 {
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
}
 +
 +
.main3 a {
 +
width: 140px;
 +
}
 +
 +
.main3:hover .sub3 {
 +
max-width: 999px;
 +
max-height: 50px;
 +
}
 +
.btn-bg3 {
 +
background: #ff1a1a;
 +
background:rgba(255,26,26,0.4);
 +
height: 50px;
 +
width: 14px;
 +
}
 +
 +
.sub3 a:hover {
 +
background: #ffb733;
 +
background:rgba(255,26,26,0.8);
 +
}
 +
/*************************three*****************************/
 +
/*************************four*****************************/
 +
.sub4 {
 +
overflow: hidden;
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
max-width: 0;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.sub4 a {
 +
background: #a600a6;
 +
background:rgba(166,0,166,0.4);
 +
}
 +
.main4 {
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
}
 +
 +
.main4 a {
 +
width: 140px;
 +
}
 +
 +
.main4:hover .sub4 {
 +
max-width: 999px;
 +
max-height: 50px;
 +
}
 +
.btn-bg4 {
 +
background: #a600a6;
 +
background:rgba(166,0,166,0.4);
 +
height: 50px;
 +
width: 14px;
 +
}
 +
 +
.sub4 a:hover {
 +
background: #ffb733;
 +
background:rgba(166,0,166,0.8);
 +
}
 +
/*************************four*****************************/
 +
/*************************five*****************************/
 +
.sub5 {
 +
overflow: hidden;
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
max-width: 0;
 +
-webkit-transition: all 600ms ease;
 +
transition: all 600ms ease;
 +
}
 +
.sub5 a {
 +
background: #0000FF;
 +
background:rgba(0,0,255,0.4);
 +
}
 +
.main5 {
 +
display: -webkit-box;
 +
display: -webkit-flex;
 +
display: -ms-flexbox;
 +
display: flex;
 +
}
 +
 +
.main5 a {
 +
width: 140px;
 +
}
 +
 +
.main5:hover .sub5 {
 +
max-width: 999px;
 +
max-height: 50px;
 +
}
 +
.btn-bg5 {
 +
background: #0000FF;
 +
background:rgba(0,0,255,0.4);
 +
height: 50px;
 +
width: 14px;
 +
}
 +
 +
.sub5 a:hover {
 +
background: #0000FF;
 +
background:rgba(0,0,255,0.8);
 +
}
 +
/*************************five*****************************/
 +
 +
/************************************************************************************/
 +
/***********************************dropdown menu-end********************************/
 +
/************************************************************************************/
 +
</style>
 +
 +
<link rel="stylesheet" href="css/style.css"/>
 +
<title>Team: Technion 2015</title>
 +
</head>
 +
<body>
  
−
<h4>Before you start: </h4>
+
<header>
−
<p> Please read the following pages:</p>
+
<!--<a href="#" ID=igem_login>Log in</a>-->
−
<ul>
+
−
<li>  <a href="https://2015.igem.org/Requirements">Requirements page </a> </li>
+
<img src="https://static.igem.org/mediawiki/2015/f/fc/Team_Technion_Logo.png" alt="Team Logo" id="team_logo" />
−
<li> <a href="https://2015.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
+
−
</ul>
+
  
−
<div class="highlightBox">
+
<div class="main_menu">
−
<h4> Styling your wiki </h4>
+
<nav>
−
<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
+
<a href="#">
−
<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>  
+
<button class="button_main1">
−
</div>
+
<span class="btn-text">Project</span>
 +
<span class="btn-bg"></span>
 +
</button>
 +
</a>
 +
<a href="#">
 +
<button class="button_main2">
 +
<span class="btn-text">Lab Notebook</span>
 +
<span class="btn-bg"></span>
 +
</button>
 +
</a>
 +
<a href="#">
 +
<button class="button_main3">
 +
<span class="btn-text">Judging Criteria</span>
 +
<span class="btn-bg"></span>
 +
</button>
 +
</a>
 +
<a href="#">
 +
<button class="button_main4">
 +
<span class="btn-text">Human Practices</span>
 +
<span class="btn-bg"></span>
 +
</button>
 +
</a>
 +
<a href="#">
 +
<button class="button_main5">
 +
<span class="btn-text">Team</span>
 +
<span class="btn-bg"></span>
 +
</button>
 +
</a>
 +
</nav>
 +
</div>
 +
</header>
  
−
<h4> Editing your wiki </h4>
+
<!---------------------------------------dropdown menu----------------------------------->
−
<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
+
<div class="dropdown">
−
<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:Technion_Israel&action=edit"> Click here to edit this page! </a></p>
+
<a href="#">
−
<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>  
+
<img src="https://static.igem.org/mediawiki/2015/c/c1/Team_Technion_Navbar_Home.png" alt="Home" id="home_nav" />
 +
<div id="home_text">Navigate</div>
 +
</a>
 +
<nav>
 +
<div class="main1">
 +
<a href="#">Project</a>
 +
<span class="btn-bg1"></span>
 +
<div class="sub1">
 +
<a href="#">sublink1</a>
 +
<a href="#">sublink2</a>
 +
<a href="#">sublink3</a>
 +
</div>
 +
</div>
 +
<div class="main2">
 +
<a href="#">Lab Notebook</a>
 +
<span class="btn-bg2"></span>
 +
<div class="sub2">
 +
<a href="#">sublink1</a>
 +
<a href="#">sublink2</a>
 +
<a href="#">sublink3</a>
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<h1 class="abstract_title">Hello! Welcome to our temporary wiki page!</h1>
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<b>Our team is developing a treatment for male pattern baldness.</b>
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<p>
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Hair loss affects roughly 61 million people in the United States.  More than 95% of hair thinning in men is attributed to male pattern baldness, or androgenetic alopecia.  The hair loss product market is a multi-billion dollar market: in the United States alone, this market’s annual revenue is 7 billion dollars, with 3.5% annual growth rate from 2007 to 2012, yet a sufficient solution has yet to be made available. 
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The trigger for androgenetic alopecia is believed to be dihydrotestosterone (DHT), a derivative of testosterone.
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This summer, we are engineering Bacillus Subtilis, a model organism for a bacterium found naturally on the scalp, to secrete 3α-hydroxysteroid dehydrogenase (3-α-HSD).  This enzyme reduces DHT to a non-steroidically active compound, using NADPH and NADH as cofactors.
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</p>
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<p>
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Our project consists of 3 main parts: 3-α-HSD secretion by the bacterium, engineered bacterium for NADPH overproduction, and a comb as a tool to create a user-friendly experience.
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By synchronizing these parts, we hope to be able to show convincing evidence of DHT breakdown, providing a promising platform for treatment of male pattern baldness!
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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Revision as of 19:00, 14 July 2015

Team: Technion 2015

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Hello! Welcome to our temporary wiki page!

Our team is developing a treatment for male pattern baldness.

Hair loss affects roughly 61 million people in the United States. More than 95% of hair thinning in men is attributed to male pattern baldness, or androgenetic alopecia. The hair loss product market is a multi-billion dollar market: in the United States alone, this market’s annual revenue is 7 billion dollars, with 3.5% annual growth rate from 2007 to 2012, yet a sufficient solution has yet to be made available. The trigger for androgenetic alopecia is believed to be dihydrotestosterone (DHT), a derivative of testosterone. This summer, we are engineering Bacillus Subtilis, a model organism for a bacterium found naturally on the scalp, to secrete 3α-hydroxysteroid dehydrogenase (3-α-HSD). This enzyme reduces DHT to a non-steroidically active compound, using NADPH and NADH as cofactors.

Our project consists of 3 main parts: 3-α-HSD secretion by the bacterium, engineered bacterium for NADPH overproduction, and a comb as a tool to create a user-friendly experience. By synchronizing these parts, we hope to be able to show convincing evidence of DHT breakdown, providing a promising platform for treatment of male pattern baldness!

Contact Us