Difference between revisions of "Team:KU Leuven/Wetlab"
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<p>We decided to work on the fundamental mechanisms behind pattern formation. We design two bacteria strains which interact with each other. To achieve our goal, the link between wet lab and modeling will be crucial to the successful design of our experiments. | <p>We decided to work on the fundamental mechanisms behind pattern formation. We design two bacteria strains which interact with each other. To achieve our goal, the link between wet lab and modeling will be crucial to the successful design of our experiments. | ||
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| − | <a href="https://2015.igem.org/Team:KU_Leuven/ | + | <a href="https://2015.igem.org/Team:KU_Leuven/Wetlab/Background">Read more</a> |
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Revision as of 14:07, 28 July 2015
Research
We designed a circuit capable of producing patterns in a controlled way. Using a modified and temperature-sensitive lambda repressor (cI), we can trigger this structure formation at desired points in time. This time-dependent controllability, together with the possibility to change many different parameters and output signals, leads to an enormous tunability in the creation of the patterns, providing advancements in a variety of industrial processes like for example the creation of novel bio-materials. On the other hand, this fundamental project could also speed up medical research projects on among others tumor formation and tissue regeneration.
Background
We decided to work on the fundamental mechanisms behind pattern formation. We design two bacteria strains which interact with each other. To achieve our goal, the link between wet lab and modeling will be crucial to the successful design of our experiments.
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Parts
Swift and smart in actions to design the plasmids, quantify the parameters and to create the patterns. Join us in our exciting journey.
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Methods
The modeling team fit models to the data obtained by the wet lab. Continuous and hybrid models will be used. Hybrid models are models which have a discrete and continuous part. Synergically, simulations from the cyber lab will aid tuning the experimental conditions that lead to the desirable patterns.
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Results
Diverse with respect to thoughts, perspectives, nationalities and languages, yet bound together by our enthusiasm for science and research. Would you like to know more about us?
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