Difference between revisions of "Team:Aalto-Helsinki/Modeling micelle"
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<p>--Basic picture of micelle to explain what is micelle here? Or is it essential since we explain it at the next part?--</p> | <p>--Basic picture of micelle to explain what is micelle here? Or is it essential since we explain it at the next part?--</p> | ||
| − | <p>We have made a <a href="https://2015.igem.org/Team:Aalto-Helsinki/Modeling_synergy">model of effectiveness of having enzymes close together</a>, but our team also wanted to know if the micelle structure was possible at the first place. We know (references as links for this statement!) that it is possible to form the micelle without any proteins at the end and with green fluorecent protein, but could CAR and ADO be part of this kind of structure? </p> | + | <p>We have made a <a href="https://2015.igem.org/Team:Aalto-Helsinki/Modeling_synergy">model of effectiveness of having enzymes close together</a>, but our team also wanted to know if the micelle structure was possible at the first place. We know (references as links for this statement!) that it is possible to form the micelle without any proteins at the end and with green fluorecent protein (Gfp), but could CAR and ADO be part of this kind of structure? </p> |
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<p>--picture of two amphiphilic proteins with ADO and CAR where all the above numbers are marked as well as total lengths--</p> | <p>--picture of two amphiphilic proteins with ADO and CAR where all the above numbers are marked as well as total lengths--</p> | ||
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| − | <h2>Calculations</h2> | + | <h2>Calculations for Ado and Car</h2> |
<!--<p>We can estimate how many amphiphilic proteins we can theoretically fit in one micelle by calculating how big solid angles they take with attached enzymes. The easiest way to estimate the solid angles is to think the amphiphilic proteins linked with enzymes as cones. We can calculate the solid angle $\Omega$ for these by \[ \Omega = 2\pi \left( 1-\cos(\theta) \right), \] where $\theta$ is half of the apex angle. So for CAR we get \[ \Omega_{CAR} = 2\pi \left( 1-\cos\left( \arctan\left(\frac{3.5}{14.1}\right)\right) \right) \approx 0.185 \text{ rad} \] and for ADO \[ \Omega_{ADO} = 2\pi \left( 1-\cos\left( \arctan\left(\frac{2}{9.8}\right)\right) \right) \approx 0.127 \text{ rad}.\]</p> | <!--<p>We can estimate how many amphiphilic proteins we can theoretically fit in one micelle by calculating how big solid angles they take with attached enzymes. The easiest way to estimate the solid angles is to think the amphiphilic proteins linked with enzymes as cones. We can calculate the solid angle $\Omega$ for these by \[ \Omega = 2\pi \left( 1-\cos(\theta) \right), \] where $\theta$ is half of the apex angle. So for CAR we get \[ \Omega_{CAR} = 2\pi \left( 1-\cos\left( \arctan\left(\frac{3.5}{14.1}\right)\right) \right) \approx 0.185 \text{ rad} \] and for ADO \[ \Omega_{ADO} = 2\pi \left( 1-\cos\left( \arctan\left(\frac{2}{9.8}\right)\right) \right) \approx 0.127 \text{ rad}.\]</p> | ||
<p>--picture of this cone-like structure--</p>--> | <p>--picture of this cone-like structure--</p>--> | ||
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| + | <h2>Calculations for Gfp</h2> | ||
<h1>Discussion</h1> | <h1>Discussion</h1> | ||
Revision as of 10:12, 3 August 2015
