Difference between revisions of "Team:TCU Taiwan"

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<span style="font-family:Levenim MT;"><font size="4">Our bacteria will going to express antimicrobial peptides to solve the rising problem of bacterial resistance. Our target is to develop it into a potential material of wound dressing. So we will test the peptides on Methicillin-Resistant Staphylococcus aureus to know it's ability to kill the Methicillin-Resistant Staphylococcus aureus. And we will always test these peptides in human cell culture using the HaCaT cell line and human fibroblasts cell to check it's ability to help wounds healing.</font>
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<span style="font-family:Levenim MT;"><font size="4">&nbsp;&nbsp;"Ouch! It's hurt!" At this instant, we might have got hurt already. As the wound appears on the skin, we became vulnerable to bacterial infection. Bacterial infections could slow down the wound recovery. In some cases, if the infection is not properly treated, it could lead to severe consequences or even devastating amputation. Currently, antibiotic is the method of choice to fight bacterial infection. However due to over use of antibiotics drug-resistant bacteria frequently appear, such as MRSA. The problem of MRSA effect around the world. In Taiwan, from 2005 to 2014, there are over 50% bacterial infection is cause by MRSA. These are the problems we faced in our daily life. </br></br></font>
  
<font size="4">Our target is to develop antimicrobial peptides into a potential material of wound dressing. Our bacteria will express two kinds of antimicrobial peptides: Epinecidin-1 and Signiferin . Signiferin have the great ability to kill Methicillin-Resistant Staphylococcus aureus that had already proved by 2013 iGEM team:TU-Delft. Epinecidin-1 has the ability to help wounds healing. We let Ecoli to express them into culture medium and purified it to make wound dressing.</font></span>
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<font size="4">&nbsp;&nbsp; To solve this problem, we apply Antimicrobial peptide. Antimicrobial peptides (AMPs), are stable peptides that have extensive ability in bactericidal effects. Often time bacterial infection prevents wounds healing. We apply E. coli to express AMPs and purified it. The objective of this project is to combine AMPs and dressing to develop into a potential medical dressing. </font></span>
 
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Revision as of 14:53, 5 August 2015









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HumanPractice

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About Our Project

  "Ouch! It's hurt!" At this instant, we might have got hurt already. As the wound appears on the skin, we became vulnerable to bacterial infection. Bacterial infections could slow down the wound recovery. In some cases, if the infection is not properly treated, it could lead to severe consequences or even devastating amputation. Currently, antibiotic is the method of choice to fight bacterial infection. However due to over use of antibiotics drug-resistant bacteria frequently appear, such as MRSA. The problem of MRSA effect around the world. In Taiwan, from 2005 to 2014, there are over 50% bacterial infection is cause by MRSA. These are the problems we faced in our daily life.

   To solve this problem, we apply Antimicrobial peptide. Antimicrobial peptides (AMPs), are stable peptides that have extensive ability in bactericidal effects. Often time bacterial infection prevents wounds healing. We apply E. coli to express AMPs and purified it. The objective of this project is to combine AMPs and dressing to develop into a potential medical dressing.

































             
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tcutaiwan@gmail.com
No.701, Sec. 3, Zhongyang Rd. Hualien 97004, Taiwan