Difference between revisions of "Team:OUC-China"

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+
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+
  <div class="headertiltle"><a href="https://2015.igem.org/Team:BostonU">Boston University iGEM 2015 </a></div>
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                    <li class="navTwo" id="navParts"><a href="https://2015.igem.org/Team:China_Tongji/Achivement">Parts</a></li>
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                    <li class="navTwo" id="navEquipment"><a href="https://2015.igem.org/Team:China_Tongji/Achivement">Equipment</a></li>
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                    <li class="navTwo" id="navJudgingForm"><a href="https://2015.igem.org/Team:China_Tongji/Achivement">Judging Form</a></li>
+
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+
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+
        <div class="navOne" id="divTeam"><a class="navOneA" id="Team" href="https://2015.igem.org/Team:China_Tongji/Team">Team <img src="https://static.igem.org/mediawiki/2015/0/07/China_Tongji_2015_dropdown_arrow.png"></a>
+
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                <li class="navTwo" id="navMembers"><a href="https://2015.igem.org/Team:China_Tongji/Team">Members</a></li>
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+
                <li class="navTwo" id="navSponsor"><a href="https://2015.igem.org/Team:China_Tongji/Team">Sponsor</a></li>
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+
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+
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+
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+
                <li class="navTwo" id="navHumanPractice"><a href="https://2015.igem.org/Team:China_Tongji/Outreach">Human Practice</a></li>
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                <li class="navTwo" id="navCollaboration"><a href="https://2015.igem.org/Team:China_Tongji/Outreach">Collaboration</a></li>
+
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+
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+
        <div class="navOne" id="divSafety"><a class="navOneA" id="Safety" href="https://2015.igem.org/Team:China_Tongji/Safety">Safety</a></div>
+
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+
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+
  
<!--content start-->
+
          <div class="igemicon">
 +
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 +
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 +
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+
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+
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+
            <li><a href="https://2015.igem.org/Team:BostonU">Home</a></li>
    <!-- maincontent start here -->
+
<li><a href="https://2015.igem.org/Team:BostonU/Team">Team</a></li>
        <!-- 滚动图片 -->
+
<li><a href="https://2015.igem.org/Team:BostonU/Project">Project</a></li>
      <div id="oneMorePic">
+
<li><a href="https://2015.igem.org/Team:BostonU/Notebook">Notebook</a></li>
        <img class="button picMove" id="moveLeft" src="https://static.igem.org/mediawiki/2015/d/d9/China_Tongji-picLeftMove.png">
+
<li><a href="https://2015.igem.org/Team:BostonU/Attributions">Attributions</a></li>
            <img class="button picMove" id="moveRight" src="https://static.igem.org/mediawiki/2015/f/f3/China_Tongji-picRightMove.png">
+
<li><a href="https://2015.igem.org/Team:BostonU/Collaborations">Collaborations</a></li>
            <div class="picPosition">
+
<li><a href="https://2015.igem.org/Team:BostonU/Practices">Human Practices</a></li>
            <img class="button picPositionIndex" src="https://static.igem.org/mediawiki/2015/2/2c/China_Tongji-picPosition.png">
+
<li><a href="https://2015.igem.org/Team:BostonU/Safety">Safety</a></li>
                <img class="button picPositionIndex" src="https://static.igem.org/mediawiki/2015/2/2c/China_Tongji-picPosition.png">
+
<li><a href="https://2015.igem.org/Team:BostonU/Modeling">Modeling</a></li>
            </div>
+
<li><a href="https://2015.igem.org/Team:BostonU/Measurement">Measurement</a></li>
 
+
<li><a href="https://2015.igem.org/Team:BostonU/Software">Software</a></li>
        </div>
+
<li><a href="https://2015.igem.org/Team:BostonU/Entrepreneurship">Entrepreneurship</a></li>
        <!-- 一级标题块 -->
+
</ul>
        <div class="titleOneBlock">
+
</div>
        <div class="titleButton"><a id="buttonProject" href="https://2015.igem.org/Team:China_Tongji/Project">Project</a></div>
+
          <div class="titleButton"><a id="buttonNotebook" href="https://2015.igem.org/Team:China_Tongji/Notebook">Notebook</a></div>
+
          <div class="titleButton"><a id="buttonAchivement" href="https://2015.igem.org/Team:China_Tongji/Achivement">Achivement</a></div>
+
          <div class="titleButton"><a id="buttonOutreach" href="https://2015.igem.org/Team:China_Tongji/Outreach">Outreach</a></div>
+
          <div class="titleButton"><a id="buttonSafety" href="https://2015.igem.org/Team:China_Tongji/Safety">Safety</a></div>
+
        </div>
+
        <!-- 项目介绍 -->
+
      <div class="dividerNone"></div>
+
    <p class="titleOne" id="ProjectIntroduction">Project Introduction</p> 
+
        <div class="divider"></div>
+
    <p class="contentP">In our project, we will use the technology of optogenetic and use light of different wave produced by the special light source assembled by ourselves to control the moving of C.elegans, construct a movement controlling system and bulid an amusement park of C.elegans.</p>
+
<p class="contentP">We will try to design our special parts and express channalrhodopsin in specific C.elegans' neurons. To accomplish our goals to express channalrhodopsin in single neuron, we make the use of cre- loxp system and the overlapping of promoters. We not only use the traditional channalrhodopsin,chR2,but also try to express the novel channelrhodopsin, Blink, and other fancy channelrhodopsins which have never been tested in C.elegans.</p>
+
<p class="contentP">And we will also get some parts and assemble those parts into a new equipment which can serves as the light source of our experiment.Then we will use computer controlling that lightsource to change the light which can activate or suppress the channelrhodopsin. By doing that, we can try to control the behaviours of C.elegans such as moving forwards or twisting more effectively.</p>
+
<p class="contentP">What's more,we will express GFP,YFP,mcherry in E.coli. By combining the color of microorgasims and C.elegans, we want to construct some interesting scenes to form a C.elegans' fancy world.</p>
+
<p class="contentP">This technology will be helpful in the research on neuron's function and interaction. In the future, this technology may also be used in mechanical controlling system and the theraphy of movement defect.</p>
+
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    The goal of our team this summer is to create an efficient and widely applicable workflow for splitting proteins. By splitting proteins and fusing each half to a drug-inducible domain, scientists can gain temporal control over protein expression. Using our workflow, the proteins will be translated into two inert halves that are each fused to domains that bind in the presence of an inducer drug. By introducing the drug into the system, the two inert protein halves will come together and for a fully functioning protein. In this way, scientists can further increase their control over protein function. The two types of proteins we will be testing our workflow on are the large serine integrase family and saCAS9. These proteins harness powerful mechanisms that have significant applications in the future of synthetic biology. By using our workflow, we hope to increase scientists understanding of these proteins and also provide a mechanism for increasing temporal control.
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Welcome to Our Project !

The goal of our team this summer is to create an efficient and widely applicable workflow for splitting proteins. By splitting proteins and fusing each half to a drug-inducible domain, scientists can gain temporal control over protein expression. Using our workflow, the proteins will be translated into two inert halves that are each fused to domains that bind in the presence of an inducer drug. By introducing the drug into the system, the two inert protein halves will come together and for a fully functioning protein. In this way, scientists can further increase their control over protein function. The two types of proteins we will be testing our workflow on are the large serine integrase family and saCAS9. These proteins harness powerful mechanisms that have significant applications in the future of synthetic biology. By using our workflow, we hope to increase scientists understanding of these proteins and also provide a mechanism for increasing temporal control.