Difference between revisions of "Template:IONIS Paris-test"

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<h2 class="intro wow zoomIn" wow-data-delay="0.4s" wow-data-duration="0.9s" style="padding-top:75px;">IONIS Paris iGEM</h2>
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<h1 class="intro wow zoomIn" wow-data-delay="0.4s" wow-data-duration="0.9s"   style="font-family:sans-serif; color:#B00000 " >Our project</h1>
<a href="#"><img id="site-title" class=" wow fadeInDown" wow-data-delay="0.0s" wow-data-duration="0.9s" src="https://static.igem.org/mediawiki/2015/8/83/Logo_IONIS.png" alt="logo"/></a>
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<!--img src="https://static.igem.org/mediawiki/2015/0/07/Fond_IONIS.jpg" alt="banner"-->
 
 
 
  
<!-- Introduction -->
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<div id="about"  class="container spacer about">
 
<div id="about"  class="container spacer about">
<h2 class="text-center wowload fadeInUp" style="color:#ff0000"> <big>Popularization of Synthetic Biology</big></h2>
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<h2 class="text-center wowload fadeInUp" style="color:#ff0000">Popularization of Synthetic Biology</h2>
<h3 class="text-center wowload fadeInUp">BACT'Man: The hero of the Bio-Console!</h3>   
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<h3 class="text-center wowload fadeInUp">By 2 different approaches</h3>   
 
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<div class="row">
 
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<div class="col-sm-6 wowload fadeInLeft">
<h4><i class="fa fa-gamepad"style="color:#b22222" ></i> The Bio-Console: allow BACT'Man to survive as long as possible </h4>
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<h4><i class="fa fa-gamepad" style="color:#b22222"></i> Design of a real synthetic biology game: the Bio-console </h4>
<p align="justify">Most video games are inspired by reality to create a <font style="color:#66cdaa">VIRTUAL WORLD</font>, in order to make them more realistic. When do we expect to do the opposite? Virtual draw to play with the living to revisit and perceive the gaming world in a new way and thus to have new sensations with the game. Imagine a bacterium, that you can view on your computer screen and that you can control using your joystick. </p>
+
<p align="justify">It is based on the control of engineered bacteria in a microfluidic chip connected to a computer interface. Our game is dependent on <font style="color:#66cdaa">optogenetic signals</font> leading to either the fluorescence of our bacteria in order to visualize it, or the death of our bacteria. The latter allows us to control our system leading to an efficient kill switch.</p>
<p>The Bio-Console: the first game console, where the games will not be so virtual!</p>
+
 +
 +
<h4><i class="fa fa-mobile" style="color:#b22222"></i> The mobile application: Biology, Synthetic Biology & Safety! </h4>
 +
<p align="justify"> Our team wants to<font style="color:#66cdaa"> promote Synthetic Biology</font> using an original point of view. The goal is to make this field accessible to everyone by using a playful & entertaining tool..</p>  
 
</div>
 
</div>
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<br>
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<br>
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    </div>
  
<div class="col-sm-6 wowload fadeInRight">
 
<h4><i class="fa fa-mobile" style="color:#b22222"></i> The mobile application: Biology, Synthetic Biology & Safety! </h4>
 
<p align="justify"> Follow <b>BACT’Man </b>: from the human's bowels to the iGEM laboratory. He evolves to become a super bacterium and bring the world all the innovations of synthetic biology ! To succeed, you will need to be ingenious and to discover the workings of biology. Progress, explore and help Bact’man along his trip and overcome the challenges on your way.</p>   
 
<p> Races, puzzles, speed games : biology and being a bacteria have never been so funny! </p>
 
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<h2 class="text-center  wowload fadeInUp">What do we do exactly?</h2>
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<p style="font-style:italic;color:red;border-style:solid;border-width:2px;border-color:red">Your browser either does not support HTML5 or cannot handle MediaWiki open video formats. Please consider upgrading your browser, installing the appropriate plugin or switching to a Firefox or Chrome install.</p>
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<a class="myButton" href="https://www.youtube.com/watch?v=gVtXKnW4zD0" style="color:#b0000f;background-color: #FFFFFF;">English Subtitles</a>
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<h2 class="text-center wowload fadeInUp" style="color:#ff0000">The Bio-Console </h2>
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<div class="row">
 
 
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<p align="left" ><img src="https://static.igem.org/mediawiki/2015/8/88/Schema_IONIS.png" alt="Project"  width="500" height=auto ></p>
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<!--img src="https://static.igem.org/mediawiki/2015/8/88/Schema_IONIS.png"-->
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  <h3 class="text-center wowload fadeInUp"> A Multidisciplinary Project</h3>
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<h4><i class="fa fa-gamepad" style="color:#b22222"></i> How will work our Bio-Console ? </h4>
<li>
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<p align="justify">To begin, we need our bacteria to be visible to the player. That's why we added the genes responsible for bacteria fluorescence.
<span><i class="fa fa-gamepad" style="color:#b22222"></i><b>Playful</b></span>
+
Our genetic construction will allow us to <font style="color:#66cdaa">induce bacteria fluorescence</font> through light signals.
</li>
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In this way, we can make each group of bacteria directly visible before starting of the game. 
<li>
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Then, the bacteria will be introduced in an aqueous <font style="color:#66cdaa">medium </font> having the same density as the water.
<span><i class="fa fa-cogs" style="color:#b22222"></i><b>Engineering</b></span>
+
In this environment, the bacteria will have all the molecules that allow them to survive in the game.
</li>
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There will be as well some liposomes (small capsules where the internal environment is separated by membranes from the external environment).
<li>
+
Inside of these liposomes, bacteria destructive toxins will be present, and this is where the <font style="color:#66cdaa">gameplay</font> of our game relies. 
<span><i class="fa fa-graduation-cap" style="color:#b22222"></i><b>Microfluidics</b></span>
+
Once the bacteria are fluorescent, we will introduce the aqueous medium in our microfluidic chip.
</li>
+
This chip will be placed beforehand under an optical microscope itself connected to the computer screen.
<li>
+
The aqueous medium, then forms a sort of bubble containing <font style="color:#66cdaa">BACT'Man</font> and toxins trapped in the vesicle.
<span><i class="fa fa-laptop" style="color:#b22222"></i><b>Computer Sciences</b></span>
+
This bubble will be directly controlled by the player by flows through the joystick as it is related to the computer.
</li>      
+
</p>
<li>
+
 
<span><i class="fa fa-globe" style="color:#b22222"></i><b>Safety issues</b></span>
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<h4><i class="fa fa-mobile" style="color:#b22222"></i> The goal of the game !</h4>
</li>
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<p align="justify"> The goal is simple: to allow <font style="color:#66cdaa">BACT'Man</font> to survive as long as possible.
</ul>
+
Stop him from getting in contact with the virtual lasers that will appear faster and faster as the game goes on.
 +
If <font style="color:#66cdaa">BACT'Man</font> were to be touched, a bright flash will appear at the microscope and will activate the liposomes opening.
 +
The toxins will eliminate our hero that will lose his fluorescence ... <font style="color:#66cdaa"><b>GAME OVER</b></font>
 +
</p>  
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<img src="https://static.igem.org/mediawiki/2015/3/34/Wii.jpg" alt="img01"/>
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<figcaption>
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<h2>BIO-CONSOLE</h2>
+
<p>Our reality game using bacteria<br>
+
<a href="https://2015.igem.org/Team:IONIS_Paris/Project" >View more</a></p>           
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</figcaption>
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</figure>
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<figure class="effect-oscar  wowload fadeInUp">
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<img src="https://static.igem.org/mediawiki/2015/8/8f/Application.jpg" alt="img01"/>
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<figcaption>
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<h2>APPLICATION</h2>
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<p>Bact'man, our hero<br>
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<a href="https://2015.igem.org/Team:IONIS_Paris/Project" >View more</a></p>           
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</figcaption>
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<!--https://static.igem.org/mediawiki/2015/c/c2/Schema1_IONIS.png-->
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<figure class="effect-oscar  wowload fadeInUp">
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<img style="width:auto"; src="https://static.igem.org/mediawiki/2015/1/19/NOTE.jpg" alt="img01"/>
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<figcaption>
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<h2>NOTEBOOK</h2>
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<p>Our Lab experiments notebook<br>
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<a href="https://2015.igem.org/Team:IONIS_Paris/Notebook" >View more</a></p>           
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<!--https://static.igem.org/mediawiki/2015/thumb/9/93/Notebook.jpg/600px-Notebook.jpg-->
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<img src="https://static.igem.org/mediawiki/2015/thumb/1/18/Brick-wall.png/800px-Brick-wall.png" alt="team"/>
 
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<h2>MICROFLUIDICS</h2>
 
<h2>MICROFLUIDICS</h2>
 
<p>Our challenge in achieving the Bio-console<br>
 
<p>Our challenge in achieving the Bio-console<br>
<a href="https://2015.igem.org/Team:IONIS_Paris/Project/Microfluidics" >View more</a></p>             
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<a href="https://2015.igem.org/Team:IONIS_Paris/Microfluidics" >View more</a></p>             
 
</figcaption>
 
</figcaption>
 
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</figure>
 
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<img src="https://static.igem.org/mediawiki/2015/thumb/a/a6/LABORATOIRE.png/800px-LABORATOIRE.png" alt="team"/>
 
<figcaption>
 
<h2>SAFETY</h2>
 
<p>Our safety measures<br>
 
<a href="https://2015.igem.org/Team:IONIS_Paris/Safety" >View more</a></p>           
 
</figcaption>
 
</figure>
 
<!--https://static.igem.org/mediawiki/2015/d/d5/Safety.jpg-->
 
 
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<img src="https://static.igem.org/mediawiki/2015/b/b9/WORK.jpg" alt="team"/>
 
<figcaption>
 
<h2>MODELING</h2>
 
<p>Our models<br>
 
<a href="https://2015.igem.org/Team:IONIS_Paris/Modeling" >View more</a></p>           
 
</figcaption>
 
</figure>
 
  
<figure class="effect-oscar  wowload fadeInUp">
 
<img src="https://static.igem.org/mediawiki/2015/4/40/Boston-MIT-01.png" alt="team"/>
 
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<h2>TEAM</h2>
 
<p>Our creative team that is making everything possible<br>
 
<a href="https://2015.igem.org/Team:IONIS_Paris/Team" >View more</a></p>           
 
</figcaption>
 
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<CENTER>
 
<div class="col-sm-3 col-xs-6">
 
<i class="fa fa-smile-o  fa-5x"></i><h4>13 Members</h4>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<i class="fa fa-map-marker fa-5x"></i><h4>4 Schools</h4>
 
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<i class="fa fa-gamepad  fa-5x"></i><h4>1 Bio-Console</h4>
 
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<i class="fa fa-tablet fa-5x"></i><h4>1 Mobile Application</h4>
 
</div>
 
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</div>
 
</div>
 
</div>
 
 
<!-- VIDEO -->
 
<div id="contact" class="spacer">
 
<div class="container">
 
<h2 class="text-center  wowload fadeInUp">What is iGEM ?</h2>
 
<CENTER>
 
<video width="500" height="281.25" poster="https://static.igem.org/mediawiki/2015/8/83/Logo_IONIS.png" controls>
 
<source src="https://static.igem.org/mediawiki/2015/7/73/Video-1438606819.mp4.mp4" type='video/mp4'/>
 
<source src="https://static.igem.org/mediawiki/2015/9/90/Video-1438606819.mp4.ogg" type='video/ogg; codecs="theora, vorbis"'/>
 
<source src="https://static.igem.org/mediawiki/2015/f/fb/Video-1438606819.mp4.webm" type='video/webm; codecs="vp8, vorbis"'/>
 
<a href="https://www.youtube.com/watch?v=DWUxy4g_p7w"><img border="0" src="https://static.igem.org/mediawiki/2015/8/83/Logo_IONIS.png" alt="Click to view on Youtube" width="500" height="281.25"></a>
 
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</video>
 
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</div>
 
 
<!--SPONSORS-->
 
<div class="sponsors">
 
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<br>
 
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<div class="col-sm-3 col-xs-6">
 
<a href="http://www.supbiotech.fr/en/index.aspx">
 
<img src="https://static.igem.org/mediawiki/2015/3/30/LOGO-SUPBIOTECH-2015-QUADRI.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
<div class="col-sm-3 col-xs-6">
 
<a href="http://www.e-artsup.net/">
 
<img src="https://static.igem.org/mediawiki/2015/9/98/Logo-e-artsup.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
<div class="col-sm-3 col-xs-6">
 
<a href="http://www.epita.fr/international/">
 
<img src="https://static.igem.org/mediawiki/2015/9/9b/Logo-epita-hd.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
<div class="col-sm-3 col-xs-6">
 
<a href="http://ionis-group.com/">
 
<img src="https://static.igem.org/mediawiki/2015/2/2e/Logo_ionis.jpg" alt="partners" width="150" height=auto>
 
</a>
 
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<br>
 
<div class="container contactform center">
 
 
<br>
 
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<a href="http://www.fluigent.com/">
 
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</a>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<a href="https://www.qiagen.com">
 
<img src="https://static.igem.org/mediawiki/2015/a/a0/Qiagen_logo.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<a href="https://www.neb.com/">
 
<img src="https://static.igem.org/mediawiki/2015/e/e1/NEB.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<a href="https://www.uni-freiburg.de/start-en.html?set_language=en">
 
<img src="https://static.igem.org/mediawiki/2015/5/59/Uni_Logo.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<a href="https://www.exzellenz.uni-freiburg.de/einrichtungen-en/bioss-en/bioss-en?set_language=en">
 
<img src="https://static.igem.org/mediawiki/2015/4/41/Bioss-4.jpg" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<a href="https://www.kickstarter.com/">
 
<img src="https://static.igem.org/mediawiki/2015/thumb/2/26/Kickstarter-logo-light.png/800px-Kickstarter-logo-light.png" alt="partners" width="150" height=auto>
 
</a>
 
</div>
 
 
<div class="col-sm-3 col-xs-6">
 
<a href="http://fr.ambafrance-us.org/">
 
<img src="https://static.igem.org/mediawiki/2015/b/b8/Logo_Embassy-of-France_OS%26T_300_dpi.jpg" alt="partners" width="150" height=auto>
 
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Revision as of 13:19, 6 August 2015

IONIS Paris

Popularization of Synthetic Biology

By 2 different approaches

Design of a real synthetic biology game: the Bio-console

It is based on the control of engineered bacteria in a microfluidic chip connected to a computer interface. Our game is dependent on optogenetic signals leading to either the fluorescence of our bacteria in order to visualize it, or the death of our bacteria. The latter allows us to control our system leading to an efficient kill switch.

The mobile application: Biology, Synthetic Biology & Safety!

Our team wants to promote Synthetic Biology using an original point of view. The goal is to make this field accessible to everyone by using a playful & entertaining tool..

Mobile Application



What do we do exactly?



English Subtitles

The Bio-Console

Project

How will work our Bio-Console ?

To begin, we need our bacteria to be visible to the player. That's why we added the genes responsible for bacteria fluorescence. Our genetic construction will allow us to induce bacteria fluorescence through light signals. In this way, we can make each group of bacteria directly visible before starting of the game. Then, the bacteria will be introduced in an aqueous medium having the same density as the water. In this environment, the bacteria will have all the molecules that allow them to survive in the game. There will be as well some liposomes (small capsules where the internal environment is separated by membranes from the external environment). Inside of these liposomes, bacteria destructive toxins will be present, and this is where the gameplay of our game relies. Once the bacteria are fluorescent, we will introduce the aqueous medium in our microfluidic chip. This chip will be placed beforehand under an optical microscope itself connected to the computer screen. The aqueous medium, then forms a sort of bubble containing BACT'Man and toxins trapped in the vesicle. This bubble will be directly controlled by the player by flows through the joystick as it is related to the computer.

The goal of the game !

The goal is simple: to allow BACT'Man to survive as long as possible. Stop him from getting in contact with the virtual lasers that will appear faster and faster as the game goes on. If BACT'Man were to be touched, a bright flash will appear at the microscope and will activate the liposomes opening. The toxins will eliminate our hero that will lose his fluorescence ... GAME OVER

team

BIOBRICKS

Our parts of DNA
View more

team

OPTOGENETICS

Our scientific core of the project
View more

team

MICROFLUIDICS

Our challenge in achieving the Bio-console
View more