Difference between revisions of "Team:BGU Israel/Modeling"

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<h2> Modeling</h2>
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<h1 class="firstHeading">Team:BGU Israel</h1>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Project/Phytoremediation">Phytoremediation</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Project/Physcomitrella"><i>Physcomitrella</i></a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Project/Localisation">Localization</a></li>
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                    <!---      <li><a href="https://2013.igem.org/Team:TU-Munich/Project/Posttranslationalfusions">Post-translational fusions</a></li>--->
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Project/Safety">Safety</a></li>
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                    <!--- <li><a href="https://2013.igem.org/Team:TU-Munich/Project/Transformation">Transformation</a></li> --->
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Results/BioBricks">BioBricks</a></li>
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                    <!-- <li><a href="https://2013.igem.org/Team:TU-Munich/Results/Implementation">Application</a></li>-->
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            <li><a id="modeling" href="https://2013.igem.org/Team:TU-Munich/Modeling/Overview">Modeling</a>
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                <ul>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Modeling/Protein_Predictions">Protein Predictions</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Modeling/Kill_Switch">Kill Switch</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Modeling/Enzyme">Enzyme Kinetics</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Modeling/Filter">Filter Model</a></li>
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                </ul>
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            <li><a id="team" href="https://2013.igem.org/Team:TU-Munich/Team/Members">Team</a>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Team/Members">Members</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Team/Statistics">Timeline</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Team/Attributions">Attributions</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Team/Judging">Judging</a></li>
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            <li><a id="human_practice" href="https://2013.igem.org/Team:TU-Munich/HumanPractice/Overview">Outreach</a>
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                <ul>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/HumanPractice/Interviews">Expert Counsel</a></li>
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/HumanPractice/GMO">GMO release</a></li>
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                    <!--- <li><a href="https://2013.igem.org/Team:TU-Munich/HumanPractice/Discussion">Discussion</a></li>---->
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                    <!--- <li><a href="https://2013.igem.org/Team:TU-Munich/HumanPractice/Conferences">Conferences</a></li>--->
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                    <li><a href="https://2013.igem.org/Team:TU-Munich/Results/How_To">Tutorials</a></li>
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<h4>Note</h4>
 
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<p>In order to be considered for the <a href="https://2015.igem.org/Judging/Awards#SpecialPrizes">Best Model award</a>, you must fill out this page.</p>
 
 
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<p>Mathematical models and computer simulations provide a great way to describe the function and operation of BioBrick Parts and Devices. Synthetic Biology is an engineering discipline, and part of engineering is simulation and modeling to determine the behavior of your design before you build it. Designing and simulating can be iterated many times in a computer before moving to the lab. This award is for teams who build a model of their system and use it to inform system design or simulate expected behavior in conjunction with experiments in the wetlab.</p>
 
  
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            <a class="button physco" href="https://2013.igem.org/Team:TU-Munich/Project/Physcomitrella">Physco</a>
 +
            <a class="button safety" href="https://2013.igem.org/Team:TU-Munich/Project/Safety">Safety</a>
 +
            <a class="button judging" href="https://2013.igem.org/Team:TU-Munich/Team/Judging">Judging</a>
 +
        </div>
 +
 +
<h2> <span class="mw-headline" id="PhyscoFilter_.E2.80.93_Clean_different."> hyscoFilter &ndash; Clean different. </span></h2>
 +
        <p>Despite the huge investment in research and the development of a variety of treatment methods, cancer is still a major cause of death in the world.
 +
            <br /> Today, both surgical and pharmacological treatments against most types of cancer are not accurate enough to identify and treat the disease on a cellular level.
 +
            On the other hand, novel biological treatments being developed were only found effective for a relatively small number of patients.
 +
            <br />In cancer, many cellular and molecular processes take place, enabling the tumor to develop and spread in the body.
 +
            <br />We believe that it is possible to take advantage of the many typical biological mechanisms of cancer cells, by developing a synthetic biology-based system for identifying and treating cancer on a cellular level.
 +
            Together as a team, we developed a modular system which identifies numerous genetic changes in cancer cells and responds by activating a synthetic machine that executes a cell suicide program or enables color-based "tagging" of the cells for tumor detection, ensuring complete surgical removal.</p>
 +
       
 +
       
 +
       
 +
 +
        <right><iframe style="box-shadow: 1px 1px 2px rgba(0, 0, 0, 0.2);padding: 5px;margin: 5px;background-color: white;" src="http://player.vimeo.com/video/76195786" width="900" height="510" frameborder="0" webkitAllowFullScreen mozallowfullscreen allowFullScreen></iframe></right>
 +
</p>
 +
<h2> <span class="mw-headline" id="Achievements"> Achievements </span></h2>
 +
<p><div class="thumb tright" id="blubberkolben">
 +
    <div class="thumbinner" style="width:400px;">
 +
        <a href="/File:TUM13_blubbern-stop.gif" class="image">
 +
            <img alt="" src="https://static.igem.org/mediawiki/2013/a/ab/TUM13_blubbern-stop.gif" width="400" class="thumbimage" />
 +
        </a>
 +
        <div class="thumbcaption">
 +
            <div class="magnify">
 +
                <a href="/File:TUM13_Physco-lifecycle.png" class="internal" title="Enlarge">
 +
                    <img src="/wiki/skins/common/images/magnify-clip.png" width="15" height="11" alt="" />
 +
                </a>
 +
            </div>
 +
        Hover over the picture!<br />Then you can actually <b>HEAR</b> the sound in our laboratory.
 +
        </div>
 +
    </div>
 +
</div>
 +
</p>
 +
<div class="achievements">
 +
<h4> <span class="mw-headline" id="European_Jamboree_results:"> European Jamboree <a href="https://igem.org/Results?year=2013&amp;region=All&amp;division=igem" class="external text" rel="nofollow">results</a>: </span></h4>
 +
<ul><li> Gold medal
 +
</li><li> Best Wiki
 +
</li><li> European First Runner Up
 +
</li></ul>
 +
<h4> <span class="mw-headline" id="World_Jamboree_results:"> World Jamboree <a href="https://igem.org/Results?year=2013&amp;region=All&amp;division=igem" class="external text" rel="nofollow">results</a>: </span></h4>
 +
<ul><li> Best Environment Project
 +
</li><li> World First Runner Up
 +
</li></ul>
 +
<h4> <span class="mw-headline" id="Business_plan_competitions_after_iGEM:"> Business plan competitions after iGEM: </span></h4>
 +
<ul><li> 1<sup>st</sup> place at the <a href="http://www.tum.de/die-tum/aktuelles/pressemitteilungen/kurz/article/31350/" class="external text" rel="nofollow">TUM IdeAward</a>
 +
</li><li> 2<sup>nd</sup> place at the <a href="http://www.presseportal.de/print/2731699-projekt-zum-internet-der-dinge-gewinnt-hochschulwettbewerb-der.html" class="external text" rel="nofollow">Be.Project Competition</a>
 +
</li><li> 3<sup>rd</sup> place in the second round of the <a href="http://www.tum.de/wirtschaft/entrepreneurship/entrepreneurship-news/artikel/article/31515/" class="external text" rel="nofollow">Munich Business Plan Competition</a>
 +
</li></ul>
 +
</div>
 +
<h2> <span class="mw-headline" id="Sponsors"> Sponsors </span></h2>
 
<p>
 
<p>
−
Here are a few examples from previous teams:
+
<a class="sponsor" href="http://www.tum.de/"><img src="https://static.igem.org/mediawiki/2013/9/97/Logo_TU-Muenchen_01.png" width="190px"></a>
 +
<a class="sponsor" href="http://wzw.tum.de/"><img src="https://static.igem.org/mediawiki/2013/a/ac/Wzwlogo2.png" width="210px"></a>
 +
<a class="sponsor" href="http://biologische-chemie.userweb.mwn.de/index.html"><img src="https://static.igem.org/mediawiki/2013/0/05/Unbenannt.PNG" width="190px"></a>
 +
<a class="sponsor" href="http://www.daad.de/de/index.html"><img src="https://static.igem.org/mediawiki/2013/f/f7/TUM13_DAAD.jpg" width="120px"></a>
 +
<a class="sponsor" href="http://www.geneious.com/"><img src="https://static.igem.org/mediawiki/2012/8/82/TUM_Geneious.png" width="190px"></a>
 +
<a class="sponsor" href="http://www.eurofins.de/"><img src="https://static.igem.org/mediawiki/2013/b/bc/TUM_Eurofins.png" width="200px"></a>
 +
<a class="sponsor" href="http://www.mathworks.de/"><img src="https://static.igem.org/mediawiki/2013/0/0c/TUM13_MathWorks.png" width="200px"></a>
 +
<a class="sponsor" href="http://www.ika.com/"><img src="https://static.igem.org/mediawiki/2013/9/9d/TUM13_IKA.png" width="105px"></a>
 +
<a class="sponsor" href="http://www.neb.com/"><img src="https://static.igem.org/mediawiki/2013/5/50/TUM13_Sponsor_NEB.jpg" width="155px"></a>
 +
<a class="sponsor" href="http://www.promega.de/"><img src="https://static.igem.org/mediawiki/2013/f/f0/Promega-300.jpg" width="175px"></a>
 +
<a class="sponsor" href="http://www.qiagen.com/"><img src="https://static.igem.org/mediawiki/2013/6/60/TUM13_Sponsor_Qiagen.png" width="100px"></a>
 +
<a class="sponsor" href="http://www.iba-lifesciences.com/"><img src="https://static.igem.org/mediawiki/2013/9/9c/Iba_logo_claim_r_farbe.jpg" width="180px"></a>
 +
<a class="sponsor" href="http://eu.idtdna.com/site/"><img src="https://static.igem.org/mediawiki/2013/1/13/Bonn_sponsor_idt.jpg" width="180px"></a>
 +
<a class="sponsor" href="http://www.thermoscientific.com"><img src="https://static.igem.org/mediawiki/2013/e/ed/TUM13_Sponsor_logo_Thermo.jpg" width="140px"></a>
 +
<a class="sponsor" href="http://www.erasynbio.eu/"><img src="https://static.igem.org/mediawiki/2013/5/58/Logo_ERASynBio.png" width="180px"></a>
 +
<div class="visualClear"></div>
 +
<a class="sponsor" style="float: none; margin: 10px auto;" href="http://www.roche.com/"><img src="https://static.igem.org/mediawiki/2013/d/d2/TUM13_Roche.jpg" height="80px"></a>
 +
 
 +
<center style="margin-top: 10px;"><a href="http://www2.clustrmaps.com/user/c81109e0d" id="clustrMapsLink"><img src="http://www2.clustrmaps.com/stats/maps-no_clusters/2013.igem.org-Team-TU-Munich-thumb.jpg" style="border:0px;" alt="Locations of visitors to this page" title="Locations of visitors to this page" id="clustrMapsImg" onerror="this.onerror=null; this.src='http://clustrmaps.com/images/clustrmaps-back-soon.jpg'; document.getElementById('clustrMapsLink').href='http://clustrmaps.com';" width="150" /></a></center>
 +
 
 
</p>
 
</p>
−
<ul>
+
</div>
−
<li><a href="https://2014.igem.org/Team:ETH_Zurich/modeling/overview">ETH Zurich 2014</a></li>
+
</div>
−
<li><a href="https://2014.igem.org/Team:Waterloo/Math_Book">Waterloo 2014</a></li>
+
<p>
−
</ul>
+
 
 +
<div id="social-footer">
 +
<a id="gotop" href="#"></a>
 +
<div id="annotator">
 +
  <h2>AutoAnnotator:</h2>
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  <form action="https://2013.igem.org/Team:TU-Munich/Results/AutoAnnotator" method="get">
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    <input type="text" name="annotator" value="Enter BioBrick number or nucleotide sequence" onblur="if(this.value == '') this.value='Enter BioBrick number or nucleotide sequence'" onfocus="if(this.value == 'Enter BioBrick number or nucleotide sequence') this.value=''" /><br />
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<div id="follow">
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    <a id="mail" href="mailto:igem@wzw.tum.de"></a>
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    <a id="facebook" href="https://www.facebook.com/pages/iGEM-TU-M%C3%BCnchen/149746078408629" target="blank"></a>
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  </div>
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</div>
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<div id="address">
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  <h2>Address:</h2>
 +
  <p>iGEM Team TU-Munich<br />
 +
    Emil-Erlenmeyer-Forum 5<br />
 +
    85354 Freising, Germany</p>
 +
  <p>Email: <a id="mail" href="mailto:igem@wzw.tum.de">igem@wzw.tum.de</a><br />
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    Phone: +49 8161 71-4351</p>
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Revision as of 15:15, 8 August 2015

Team:BGU Israel - 2015.igem.org

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Team:BGU Israel


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hyscoFilter – Clean different.

Despite the huge investment in research and the development of a variety of treatment methods, cancer is still a major cause of death in the world.
Today, both surgical and pharmacological treatments against most types of cancer are not accurate enough to identify and treat the disease on a cellular level. On the other hand, novel biological treatments being developed were only found effective for a relatively small number of patients.
In cancer, many cellular and molecular processes take place, enabling the tumor to develop and spread in the body.
We believe that it is possible to take advantage of the many typical biological mechanisms of cancer cells, by developing a synthetic biology-based system for identifying and treating cancer on a cellular level. Together as a team, we developed a modular system which identifies numerous genetic changes in cancer cells and responds by activating a synthetic machine that executes a cell suicide program or enables color-based "tagging" of the cells for tumor detection, ensuring complete surgical removal.

Achievements

Hover over the picture!
Then you can actually HEAR the sound in our laboratory.

European Jamboree results:

  • Gold medal
  • Best Wiki
  • European First Runner Up

World Jamboree results:

  • Best Environment Project
  • World First Runner Up

Business plan competitions after iGEM:

Sponsors

Locations of visitors to this page

Retrieved from "https://2013.igem.org/Team:TU-Munich"