Difference between revisions of "Team:NCTU Formosa/Description"

Line 111: Line 111:
 
<div class="photo1"></div>
 
<div class="photo1"></div>
 
<div class="content2">
 
<div class="content2">
Cancers, the last thing that human beings would like to get involved. Everyone wishes to have clean bills of health no matter in what age. Nowadays, the top cancers include lung cancer, colorectal cancer, breast cancer, melanoma and thyroid cancer. According to National Cancer Institute(NCI), in 2015, the estimated number of new cases of these cancers are 724,410. The estimated death cases of these cancers are 260,360.So, it is inevitable for some situations to suffer cancers, and we would all be desperate to have the most effective and appropriate therapies to beat up cancers. Eventually, targeted drug, a precise therapy directly identifying the cancer cells has been invented.</div>  
+
Cancer has the crucial impact on individuals, family and society around the globe. According to the cancer statistics published by World Health Organization (WHO) in 2015, there were approximately 14 million new cases and 8.2million cancer related deaths in 2012. It’s also expected that cancer cases will rise from 14 million to 22 million within the next two decades. <br>Even though governments and health-care organizations try hard to prevent and reduce the rising number of cancer cases, cancers still risk everyone’s life. As the result, the notion of precise and efficient personal therapy─targeted drug therapy arises.</div>  
 
<div class="content3">
 
<div class="content3">
Targeted drug therapy becomes widely used over time. As we known that targeted drug therapies are <font color="#AC1F4A">more precisely</font>  attack cancer cells, which can <font color="#AC1F4A">increase the treatment efficiency</font> by a large margin. In Figure 1, in 2003, targeted drug therapy is not commonly used compared with other therapies, accounting for only 11% usage. Over one decade, it is estimated that the usage of targeted drug therapy dramatically <font color="#AC1F4A">increases to 46%</font>. It becomes the top therapy in cancer treatments among others. According to the statistics, the usage of targeted drugs therapy does have effective treatment in cancer, decreasing the morality of cancer and increasing the five-year survival rate after treatment.</div>
+
TStudies show that targeted drug therapy can attack cancer cells more precisely and enhance the efficiency of treatment by a large margin. According to the statistics, the usage rate of targeted drug therapy has increased within ten years. In Figure, in 2003, targeted drug therapy is not commonly used compared with other therapies, accounting for only 11% usage. Over one decade, it is estimated that the usage of targeted drug therapy dramatically increases to 46%. By this estimation, targeted drugs will become the commonly used therapy in cancer treatments among others in the future.</div>
 
<div class="photo2"></div>
 
<div class="photo2"></div>
 
<div class="content4">
 
<div class="content4">
One of a kind of targeted drugs therapy is monoclonal
+
Targeted drugs therapy utilize compounds that are capable of inhibiting targeted molecules on cancer cells which send message along signaling pathways in cell growth, cell division or cell death. Via specific binding to targeted biomarkers, targeted drugs show more accurate attack to cancer cells and less harmful damage to normal tissues, bringing a new perspective in the treatment of cancer. [1] Although targeted drugs treatments can lead to the dramatic regressions of solid tumors, the responses are often short-lived because resistant cancer cells arise after a period of treatment. The major strategy proposed for overcoming the resistance is combination therapy. The clinical and preclinical researches further indicated that the combination therapy which treats cancer with multiple drugs can attain greater effects than using only one. There are less probability that a single mutation will cause cross-resistance to both drugs.[2] Furthermore, the targeted therapy is a major step forward for many cancers, especially advanced cancer. Physicians and researchers are now focusing on the development of targeted drugs, and creating a new era of personalized cancer treatment.[3]</div>
antibody. It blocks the growth and spread of cancer by interfering with
+
specific molecules ("molecular targets") that are involved in the growth,  
+
progression,and spread of cancers.Furthermore, the research also
+
indicated that utilizing different targeted drugs to treat cancers simultaneously
+
attain greater effects than only using one targeted drug. However, targeted  
+
drugs therapy must  treat patients in the proper condition to reach the best
+
effect of the therapy. What's worse, the improper usage of targeted drugs
+
therapy would not only waste money and medical resources but also
+
cause the invalid treatment result to patients.Above all, defining whether
+
to use the targeted drugs might be the crucial pointof targeted drugs
+
therapy.That is, if doctor can prescribe the proper targeted drugs that
+
specific to every patient's condition, it will reach to a direct personalized  
+
medicine method for using targeted drugs therapy .
+
Therefore, NCTU_Formosa focuses on creating a multimarker
+
diagnosis platform for helping doctors to judge whether to use monoclonal
+
antibody targeted drugs by innovative method directly.</div>
+
 
<div class="photo3"></div>
 
<div class="photo3"></div>
 
<div style="position:relative;">
 
<div style="position:relative;">

Revision as of 04:56, 2 September 2015

Cancer has the crucial impact on individuals, family and society around the globe. According to the cancer statistics published by World Health Organization (WHO) in 2015, there were approximately 14 million new cases and 8.2million cancer related deaths in 2012. It’s also expected that cancer cases will rise from 14 million to 22 million within the next two decades.
Even though governments and health-care organizations try hard to prevent and reduce the rising number of cancer cases, cancers still risk everyone’s life. As the result, the notion of precise and efficient personal therapy─targeted drug therapy arises.
TStudies show that targeted drug therapy can attack cancer cells more precisely and enhance the efficiency of treatment by a large margin. According to the statistics, the usage rate of targeted drug therapy has increased within ten years. In Figure, in 2003, targeted drug therapy is not commonly used compared with other therapies, accounting for only 11% usage. Over one decade, it is estimated that the usage of targeted drug therapy dramatically increases to 46%. By this estimation, targeted drugs will become the commonly used therapy in cancer treatments among others in the future.
Targeted drugs therapy utilize compounds that are capable of inhibiting targeted molecules on cancer cells which send message along signaling pathways in cell growth, cell division or cell death. Via specific binding to targeted biomarkers, targeted drugs show more accurate attack to cancer cells and less harmful damage to normal tissues, bringing a new perspective in the treatment of cancer. [1] Although targeted drugs treatments can lead to the dramatic regressions of solid tumors, the responses are often short-lived because resistant cancer cells arise after a period of treatment. The major strategy proposed for overcoming the resistance is combination therapy. The clinical and preclinical researches further indicated that the combination therapy which treats cancer with multiple drugs can attain greater effects than using only one. There are less probability that a single mutation will cause cross-resistance to both drugs.[2] Furthermore, the targeted therapy is a major step forward for many cancers, especially advanced cancer. Physicians and researchers are now focusing on the development of targeted drugs, and creating a new era of personalized cancer treatment.[3]
contact us
NCTU_Formosa APOllO   
  Engineering Building 6 EF455, 1001 University Road, Hsinchu 300, Taiwan, ROC.