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Revision as of 11:39, 8 September 2015
What is the Game Over?
Allowing the end of the game
Nature has evolved a multiple of photoreceptors able to sense light. Those systems have provide synthetic biology tools for the precise control of biological functions, offering superior spatial and temporal resolution. The research field focusing on the combination of optical method and genetic has been named «optogenetics» and can lead to the control of gene expression, cell morphology or even signaling pathway thank to light signal.
Concept
Using thermosensitive liposomes
IN CONSTRUCTION
Using toxins
IN CONSTRUCTION
Why did we choose the photoreceptor VVD ?
Contrary to other photoreceptors, VVD is a small protein with 150 amino-acids facilitating accurate molecular design and avoiding steric issue. Moreover, it is a homo-dimer when most of photo-inducible dimer are heterodimer. In addition, the use of VVD is easy; and doesn’t need any addition of co-factors: VVD works with Flavin adenine dinucleotide (FAD) which is already abundant in eukaryote and prokaryote cells. (Müller & Weber, 2013; Nihongaki, Suzuki, Kawano, & Sato, 2014)
PROJECT
Our reality game using bacteria
BIOBRICKS
Our parts of DNA
MICROFLUIDICS
Our challenge in achieving the Bio-console