Difference between revisions of "Team:Birkbeck/Practices"

This June University College London, Birkbeck and London Biohackspace attended a jointly organised iGEM boot camp featuring BioBrick making in the lab, presentations from key iGEM team advisors as well as Skype talks with iGEM Headquarters representatives, DIY spectrophotometers, wiki design and extra lab skills.

The purpose of this successful week-long event was to kickstart all team projects and bring all members to the same page in our iGEM journey. The knowledge and experience acquired by everyone enabled the individual teams to start making the most of their summer work which is now underway. All participants benefited from laboratory induction sessions, and smaller groups divided into specialised tracks.

The DIY track group assembled a functional spectrophotometer at the London Biohackspace using 3D printed components, while the Software track group learnt the basic progrsmming required in developing the iGEM wiki and submitting BioBricks to the registry. Finally, the extra lab group received insights into the most efficient cutting edge cloning technologies relevant to iGEM work.

The boot camp culminated in the Mini Jamboree where all different institution teams presented their work over the past week to the rest of the attendants including highschoolers, and the track groups also presented their specific projects. The networking opportunities throughout the boot camp strengthened our teams, and wrapped up with a fantatic snacks and drinks sleection after the jamboree!

As the Birkbeck iGEM 2015 team, we found it essential to involve the wider community in the ideas underpinning iGEM, more broadly about synthetic biology and genetic information. Since most primary schools in the UK do not have a teacher specifically trained in the sciences, we took the oportunity of a science busking at a William Tyndale Primary School in Islington. Our aim was to use fun props and games to illustrate key concepts in genetics to an eager audience of four separate classes of 9-year olds and 11-year olds.

The planning necessary before the big day was instrumental in our success. We devised scripts to involve all out team in the presentations and games while leaving room for inevitable improvisation, designed engaging and practically feasible games with a tight time limit, crafted attractive props and finally rehearsed numerous times to ensure our busk was going to be memorable.

We came up with four different games. The first one involved a talk about germs and a game where clapping children would react to glitter on their hands when a team member in our clapping row introduced it at a random time. The glitter symbolised germs, and the game showed the children unequivocally just how easily they spread through brief hand to hand contact. Our second game elegantly illustrated the notions in Mendelian genetics by using red and white beans as alleles for flower colour. The kids were given varying combinations of these beans and had to work out what colour they produced.

Cautiously, we introduced DNA as a concept to the children in our third and fourth games. We assigned volunteers a nucleotide base and through complementary binding and strand annealing we created a human DNA. Finally, paper DNA with action codes on was given to groups of pupils. After decoding their piece of DNA, the whole class acted out what it specified all at once as the DNA was “activated”.

The reactions from the most enthusiastic children were unforgettable and hilarious in equal measure, and we can safely say that even the most sceptical of kids became fascinated by the end of our busk.

What have we been doing, you ask? Well, for starters, we've been forwarding our articles for the Amoy China 2015 iGEM team whose Newsletter reaches hundreds of people. To read more about our team, go to p.9-11, and on p.59-66, we describe the kinds of human practice events we've already taken part in. For example, we talk about the iGEM London BootCamp that we jointly organised with the UCL 2015 iGEM and the London Biohackspace 2015 iGEM teams! And now we're planning another London iGEM meet (at the end of July), and a more general UK iGEM meet (at the beginning of September)! - More details on these latter 2 events, coming up soon!

To gage the importance of a cheap and simple diagnostic kit for use in rural areas in developing countries on economically neglected diseases, such as Tubercolosis, through Rachel's contacts at The Brooke we reached out to doctors in the field.