Difference between revisions of "Team:NRP-UEA-Norwich/Modeling/3D"
| Line 108: | Line 108: | ||
<h3 class="title">Glycogen</h2> | <h3 class="title">Glycogen</h2> | ||
<div class="space30"></div> | <div class="space30"></div> | ||
| − | <p class="space20"> Glycogen is the glucose storage molecule in animals, bacteria and fungi. It is a polysaccharide composed of monosaccharide glucose units linked by alpha-1,4 glycosidic bonds. Each linear chain contains approximately 13 glucose residues and a number of alpha | + | <p class="space20"> Glycogen is the glucose storage molecule in animals, bacteria and fungi. It is a polysaccharide composed of monosaccharide glucose units linked by alpha-1,4 glycosidic bonds. Each linear chain contains approximately 13 glucose residues and a number of alpha-1,6 glycosidic bonds, which allow branching, that are 3–4 residues apart. Glycogen is the analogue of starch in plants but is more extensively branched and compact.</p> |
<p class="space20">This simple model - created for our wiki by the SWEET software - shows a small section of a glycogen molecule consisting of 91 glucose units which are contained within 7 branches and 3 tiers. The 1,4 linked sections can be seen to coil into a helical shape, and the 1,6 linkages form helical branches away from the centre of the molecule.</p> | <p class="space20">This simple model - created for our wiki by the SWEET software - shows a small section of a glycogen molecule consisting of 91 glucose units which are contained within 7 branches and 3 tiers. The 1,4 linked sections can be seen to coil into a helical shape, and the 1,6 linkages form helical branches away from the centre of the molecule.</p> | ||
Revision as of 14:43, 16 September 2015
3D Modelling Overview
We built 3D models to see how changing parameters such as branching degree and the number of tiers affect the overall structure of the molecule in a chemically accurate way.
Glycogen
Glycogen is the glucose storage molecule in animals, bacteria and fungi. It is a polysaccharide composed of monosaccharide glucose units linked by alpha-1,4 glycosidic bonds. Each linear chain contains approximately 13 glucose residues and a number of alpha-1,6 glycosidic bonds, which allow branching, that are 3–4 residues apart. Glycogen is the analogue of starch in plants but is more extensively branched and compact.
This simple model - created for our wiki by the SWEET software - shows a small section of a glycogen molecule consisting of 91 glucose units which are contained within 7 branches and 3 tiers. The 1,4 linked sections can be seen to coil into a helical shape, and the 1,6 linkages form helical branches away from the centre of the molecule.
You can interact with the model using your mouse.
3D Printing Gallery
References
http://www.biotopics.co.uk/jsmol/glycogen.html
http://watcut.uwaterloo.ca/webnotes/Metabolism/glycogenStructure.html.
http://www.glycosciences.de/modeling/sweet2/doc/index.php
