Difference between revisions of "Team:Valencia UPV/Modelling/DetModel"
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<p>Basically, our aim is the biological design of a multiplexor that only expresses the genetic information <b>when, where</b> and <b>which</b> is desired by the user. The biological components that allow us this implementation in living organisms are <i>two switches, two recombinases and a library of different binding domains</i>. All those elements have been coordinated in this cascade of three different levels.</p> | <p>Basically, our aim is the biological design of a multiplexor that only expresses the genetic information <b>when, where</b> and <b>which</b> is desired by the user. The biological components that allow us this implementation in living organisms are <i>two switches, two recombinases and a library of different binding domains</i>. All those elements have been coordinated in this cascade of three different levels.</p> | ||
− | <div style="text-align:center"><img src="https://static.igem.org/mediawiki/2015/0/09/Valencia_upv_modelcircuitfull.jpg"></div> | + | <div style="text-align:center"><img src="https://static.igem.org/mediawiki/2015/0/09/Valencia_upv_modelcircuitfull.jpg"></div><br/> |
<div class="table-wrapper"><table class="alt"> | <div class="table-wrapper"><table class="alt"> | ||
− | <tr><td>Component</td><td>Symbol</td></tr> | + | <tr style="background-color:green;font-weight:bold"><td>Component</td><td>Symbol</td></tr> |
<tr><td>DB1-PIF6</td><td><img src="https://static.igem.org/mediawiki/2015/b/b3/Valencia_upv_pif6.png"></td></tr> | <tr><td>DB1-PIF6</td><td><img src="https://static.igem.org/mediawiki/2015/b/b3/Valencia_upv_pif6.png"></td></tr> | ||
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<div class="table-wrapper"><table class="alt"> | <div class="table-wrapper"><table class="alt"> | ||
− | <tr><td>Component</td><td>Symbol</td></tr> | + | <tr style="background-color:green;font-weight:bold"><td>Component</td><td>Symbol</td></tr> |
<tr><td>BD3-PIF6</td><td><img src="https://static.igem.org/mediawiki/2015/1/16/Valencia_upv_bd3pif6.png"></td></tr> | <tr><td>BD3-PIF6</td><td><img src="https://static.igem.org/mediawiki/2015/1/16/Valencia_upv_bd3pif6.png"></td></tr> |
Revision as of 09:48, 17 September 2015
Our deterministic model uses mathematical information contained in its equations, in order to provide results that depict the behavior of our device. Although how much is an important question, the value of this information overpasses the numerical frontiers, getting to the most important point when new and revolutionary devices are being tested, which is how. How does AladDNA behave is the main question that we want to answer with our modelling task. Take a sit and enjoy this wander in our mathematical chaos! The idea of our circuit can be simply represented by this picture. Basically, our aim is the biological design of a multiplexor that only expresses the genetic information when, where and which is desired by the user. The biological components that allow us this implementation in living organisms are two switches, two recombinases and a library of different binding domains. All those elements have been coordinated in this cascade of three different levels. Hello world
What is our device supposed to do? Circuit explanation
Component Symbol DB1-PIF6 PhyB-VP16 BD2-LOV2 ePDZ-VP16 BxB1
Component Symbol BD3-PIF6 BD4-LOV2 ƟC31 BD5-PIF6 BD6-LOV2
From Biochemical reactions to Mathematical equations
Mass Action Kinetics, Quasy Steady State Analysis