Difference between revisions of "Team:technion"

Line 4: Line 4:
 
<meta charset="utf-8"/>
 
<meta charset="utf-8"/>
 
 
<style type="text/css">
+
<link rel="stylesheet" type="text/css" href="https://2015.igem.org/Template:Technion/CSS?action=raw&ctype=text/css" />
+
.abstract {
+
font-size: 130%;
+
}
+
+
#top_menu_14 {
+
width: 100%;
+
}
+
 
+
#top_menu_inside {
+
width: 100%;
+
}
+
#top_menu_under {
+
width: 100%;
+
}
+
#globalWrapper {
+
width: 100%;
+
float: none;
+
}
+
#content {
+
width: 100%;
+
}
+
 
+
h1 {
+
border-bottom: none;
+
}
+
 
+
.main_menu, footer {
+
width: 650px;
+
margin: auto;
+
clear: both;
+
}
+
+
#igem_login {
+
float: right;
+
color: white;
+
background:#7f7f7f;
+
background:rgba(0,0,0,0.2);
+
}
+
+
#igem_login:hover {
+
color: blue;
+
}
+
+
#team_logo {
+
width: 400px;
+
height: auto;
+
display: block;
+
margin: auto;
+
}
+
+
.facebook_link {
+
margin-top: 5px;
+
}
+
+
body {
+
font-family: sans-serif;
+
background-image: url("https://static.igem.org/mediawiki/2015/1/1b/Team_Technion_Background_Hair.jpg");
+
}
+
+
.content {
+
width: 700px;
+
margin: auto;
+
background:#7f7f7f;
+
background:rgba(255,255,255,0.5);
+
}
+
+
.abstract {
+
position: relative;
+
text-align: left;
+
z-index: 1;
+
margin-left: 10px;
+
}
+
+
.abstract_title {
+
position: relative;
+
text-align: center;
+
z-index: 1;
+
}
+
+
+
+
/*************************footer****************/
+
footer .team_name  {
+
text-align: center;
+
color: white;
+
}
+
+
footer .connect_links {
+
width: 130px;
+
margin: auto;
+
}
+
+
footer {
+
background:#7f7f7f;
+
background:rgba(0,0,0,0.5);
+
width: 100%;
+
}
+
+
footer h3 {
+
margin-top: 0px;
+
margin-bottom: 0px;
+
color: white;
+
}
+
+
.connect_links {
+
display: flex;
+
}
+
/*************************footer-end*************/
+
+
+
+
+
+
/************************************************************************************/
+
/***********************************Buttons******************************************/
+
/************************************************************************************/
+
+
/*************************one****************/
+
.button_main1 {
+
background: #f33;
+
color: #fff;
+
border: 0;
+
padding: 1em 2em;
+
border-radius: 6px;
+
cursor: pointer;
+
border-bottom: 3px solid #e60000;
+
outline: none;
+
position: relative;
+
overflow: hidden;
+
}
+
.button_main1:hover {
+
border-bottom-width: 2px;
+
margin-top: 0px;
+
}
+
.button_main1:active,
+
.button_main1:focus {
+
border-bottom-width: 1px;
+
margin-top: 2px;
+
-webkit-animation: shakeBtn 20ms infinite;
+
animation: shakeBtn 20ms infinite;
+
}
+
.button_main1 .btn-text {
+
position: relative;
+
z-index: 1;
+
}
+
.button_main1 .btn-bg {
+
position: absolute;
+
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
+
background: linear-gradient(to bottom, #f99, #ff1a1a);
+
top: -100%;
+
left: 0;
+
width: 100%;
+
height: 200%;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.button_main1:hover .btn-bg {
+
top: 0;
+
}
+
/*************************one-end*************/
+
/*************************two****************/
+
.button_main2 {
+
background: #f33;
+
color: #fff;
+
border: 0;
+
padding: 1em 2em;
+
border-radius: 6px;
+
cursor: pointer;
+
border-bottom: 3px solid #e60000;
+
outline: none;
+
position: relative;
+
overflow: hidden;
+
}
+
.button_main2:hover {
+
border-bottom-width: 2px;
+
margin-top: 0px;
+
}
+
.button_main2:active,
+
.button_main2:focus {
+
border-bottom-width: 1px;
+
margin-top: 2px;
+
-webkit-animation: shakeBtn 20ms infinite;
+
animation: shakeBtn 20ms infinite;
+
}
+
.button_main2 .btn-text {
+
position: relative;
+
z-index: 1;
+
}
+
.button_main2 .btn-bg {
+
position: absolute;
+
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
+
background: linear-gradient(to bottom, #f99, #ff1a1a);
+
top: -100%;
+
left: 0;
+
width: 100%;
+
height: 200%;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.button_main2:hover .btn-bg {
+
top: 0;
+
}
+
/*************************two-end*************/
+
/*************************three****************/
+
.button_main3 {
+
background: #f33;
+
color: #fff;
+
border: 0;
+
padding: 1em 2em;
+
border-radius: 6px;
+
cursor: pointer;
+
border-bottom: 3px solid #e60000;
+
outline: none;
+
position: relative;
+
overflow: hidden;
+
}
+
.button_main3:hover {
+
border-bottom-width: 2px;
+
margin-top: 0px;
+
}
+
.button_main3:active,
+
.button_main3:focus {
+
border-bottom-width: 1px;
+
margin-top: 2px;
+
-webkit-animation: shakeBtn 20ms infinite;
+
animation: shakeBtn 20ms infinite;
+
}
+
.button_main3 .btn-text {
+
position: relative;
+
z-index: 1;
+
}
+
.button_main3 .btn-bg {
+
position: absolute;
+
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
+
background: linear-gradient(to bottom, #f99, #ff1a1a);
+
top: -100%;
+
left: 0;
+
width: 100%;
+
height: 200%;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.button_main3:hover .btn-bg {
+
top: 0;
+
}
+
/*************************three-end*************/
+
/*************************four****************/
+
.button_main4 {
+
background: #f33;
+
color: #fff;
+
border: 0;
+
padding: 1em 2em;
+
border-radius: 6px;
+
cursor: pointer;
+
border-bottom: 3px solid #e60000;
+
outline: none;
+
position: relative;
+
overflow: hidden;
+
}
+
.button_main4:hover {
+
border-bottom-width: 2px;
+
margin-top: 0px;
+
}
+
.button_main4:active,
+
.button_main4:focus {
+
border-bottom-width: 1px;
+
margin-top: 2px;
+
-webkit-animation: shakeBtn 20ms infinite;
+
animation: shakeBtn 20ms infinite;
+
}
+
.button_main4 .btn-text {
+
position: relative;
+
z-index: 1;
+
}
+
.button_main4 .btn-bg {
+
position: absolute;
+
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
+
background: linear-gradient(to bottom, #f99, #ff1a1a);
+
top: -100%;
+
left: 0;
+
width: 100%;
+
height: 200%;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.button_main4:hover .btn-bg {
+
top: 0;
+
}
+
/*************************four-end*************/
+
/*************************five****************/
+
.button_main5 {
+
background: #f33;
+
color: #fff;
+
border: 0;
+
padding: 1em 2em;
+
border-radius: 6px;
+
cursor: pointer;
+
border-bottom: 3px solid #e60000;
+
outline: none;
+
position: relative;
+
overflow: hidden;
+
}
+
.button_main5:hover {
+
border-bottom-width: 2px;
+
margin-top: 0px;
+
}
+
.button_main5:active,
+
.button_main5:focus {
+
border-bottom-width: 1px;
+
margin-top: 2px;
+
-webkit-animation: shakeBtn 20ms infinite;
+
animation: shakeBtn 20ms infinite;
+
}
+
.button_main5 .btn-text {
+
position: relative;
+
z-index: 1;
+
}
+
.button_main5 .btn-bg {
+
position: absolute;
+
background: -webkit-linear-gradient(top, #f99, #ff1a1a);
+
background: linear-gradient(to bottom, #f99, #ff1a1a);
+
top: -100%;
+
left: 0;
+
width: 100%;
+
height: 200%;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.button_main5:hover .btn-bg {
+
top: 0;
+
}
+
/*************************five-end*************/
+
+
/************************************************************************************/
+
/***********************************Buttons-end**************************************/
+
/************************************************************************************/
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
/************************************************************************************/
+
/***********************************dropdown menu************************************/
+
/************************************************************************************/
+
+
.dropdown {
+
position: fixed;
+
top: 10px;
+
display: inline-block;
+
float: left;
+
z-index: 999;
+
}
+
.dropdown nav {
+
max-height: 0px;
+
overflow: hidden;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.dropdown nav a {
+
display: block;
+
}
+
.dropdown:hover nav {
+
max-height: 999px;
+
}
+
.dropdown a {
+
width: 155px;
+
display: inline-block;
+
background: #33f;
+
background:rgba(0,0,0,0.4);
+
color: #fff;
+
text-decoration: none;
+
text-align: center;
+
padding: 1em 2em;
+
font-family: sans-serif;
+
}
+
+
.dropdown a:hover {
+
background: #33f;
+
background:rgba(0,0,0,0.8);
+
}
+
/*************************one*****************************/
+
.sub1 {
+
overflow: hidden;
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
max-width: 0;
+
max-height: 50px;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.sub1 a {
+
background: #ffb733;
+
background:rgba(255,183,51,0.4);
+
}
+
.main1 {
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
}
+
+
.main1 a {
+
width: 140px;
+
}
+
+
.main1:hover .sub1 {
+
max-width: 999px;
+
max-height: 50px;
+
}
+
.btn-bg1 {
+
background: #ffb733;
+
background:rgba(255,183,51,0.4);
+
height: 50px;
+
width: 14px;
+
}
+
+
.sub1 a:hover {
+
background: #ffb733;
+
background:rgba(255,183,51,0.8);
+
}
+
/*************************one*****************************/
+
/*************************two*****************************/
+
.sub2 {
+
overflow: hidden;
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
max-width: 0;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.sub2 a {
+
background: #00a600;
+
background:rgba(0,166,0,0.4);
+
}
+
.main2 {
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
}
+
+
.main2 a {
+
width: 140px;
+
}
+
+
.main2:hover .sub2 {
+
max-width: 999px;
+
max-height: 50px;
+
}
+
.btn-bg2 {
+
background: #00a600;
+
background:rgba(0,166,0,0.4);
+
height: 50px;
+
width: 14px;
+
}
+
+
.sub2 a:hover {
+
background: #ffb733;
+
background:rgba(0,166,0,0.8);
+
}
+
/*************************two*****************************/
+
/*************************three*****************************/
+
.sub3 {
+
overflow: hidden;
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
max-width: 0;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.sub3 a {
+
background: #ff1a1a;
+
background:rgba(255,26,26,0.4);
+
}
+
.main3 {
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
}
+
+
.main3 a {
+
width: 140px;
+
}
+
+
.main3:hover .sub3 {
+
max-width: 999px;
+
max-height: 50px;
+
}
+
.btn-bg3 {
+
background: #ff1a1a;
+
background:rgba(255,26,26,0.4);
+
height: 50px;
+
width: 14px;
+
}
+
+
.sub3 a:hover {
+
background: #ffb733;
+
background:rgba(255,26,26,0.8);
+
}
+
/*************************three*****************************/
+
/*************************four*****************************/
+
.sub4 {
+
overflow: hidden;
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
max-width: 0;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.sub4 a {
+
background: #a600a6;
+
background:rgba(166,0,166,0.4);
+
}
+
.main4 {
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
}
+
+
.main4 a {
+
width: 140px;
+
}
+
+
.main4:hover .sub4 {
+
max-width: 999px;
+
max-height: 50px;
+
}
+
.btn-bg4 {
+
background: #a600a6;
+
background:rgba(166,0,166,0.4);
+
height: 50px;
+
width: 14px;
+
}
+
+
.sub4 a:hover {
+
background: #ffb733;
+
background:rgba(166,0,166,0.8);
+
}
+
/*************************four*****************************/
+
/*************************five*****************************/
+
.sub5 {
+
overflow: hidden;
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
max-width: 0;
+
-webkit-transition: all 600ms ease;
+
transition: all 600ms ease;
+
}
+
.sub5 a {
+
background: #0000FF;
+
background:rgba(0,0,255,0.4);
+
}
+
.main5 {
+
display: -webkit-box;
+
display: -webkit-flex;
+
display: -ms-flexbox;
+
display: flex;
+
}
+
+
.main5 a {
+
width: 140px;
+
}
+
+
.main5:hover .sub5 {
+
max-width: 999px;
+
max-height: 50px;
+
}
+
.btn-bg5 {
+
background: #0000FF;
+
background:rgba(0,0,255,0.4);
+
height: 50px;
+
width: 14px;
+
}
+
+
.sub5 a:hover {
+
background: #0000FF;
+
background:rgba(0,0,255,0.8);
+
}
+
/*************************five*****************************/
+
+
/************************************************************************************/
+
/***********************************dropdown menu-end********************************/
+
/************************************************************************************/
+
</style>
+
 
 
<link rel="stylesheet" href="css/style.css"/>
 
 
<title>Team: Technion 2015</title>
 
<title>Team: Technion 2015</title>
 
</head>
 
</head>

Revision as of 13:34, 25 July 2015

Team: Technion 2015

Hello! Welcome to our temporary wiki page!

Our team is developing a treatment for male pattern baldness.

Hair loss affects roughly 61 million people in the United States. More than 95% of hair thinning in men is attributed to male pattern baldness, or androgenetic alopecia. The hair loss product market is a multi-billion dollar market: in the United States alone, this market’s annual revenue is 7 billion dollars, with 3.5% annual growth rate from 2007 to 2012, yet a sufficient solution has yet to be made available. The trigger for androgenetic alopecia is believed to be dihydrotestosterone (DHT), a derivative of testosterone. This summer, we are engineering Bacillus Subtilis, a model organism for a bacterium found naturally on the scalp, to secrete 3α-hydroxysteroid dehydrogenase (3-α-HSD). This enzyme reduces DHT to a non-steroidically active compound, using NADPH and NADH as cofactors.

Our project consists of 3 main parts: 3-α-HSD secretion by the bacterium, engineered bacterium for NADPH overproduction, and a comb as a tool to create a user-friendly experience. By synchronizing these parts, we hope to be able to show convincing evidence of DHT breakdown, providing a promising platform for treatment of male pattern baldness!

Contact Us