Difference between revisions of "Team:DTU-Denmark"

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{{DTU-Denmark}}
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<h2>Modular Biosynthesis</h2>
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<p>Nonribosomal peptides, polyketides and hybrids thereof are secondary metabolites that are biosynthesized by condensation of amino and/or carboxylic acids. These metabolites have a wide variety of important biological activities that include antibacterial, anticancer and immunosuppressing activities.</p>
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    <link href="/Team:DTU-Denmark/bootstrap.css?action=raw&ctype=text/css" rel="stylesheet">
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    <link href="/Team:DTU-Denmark/style.css?action=raw&ctype=text/css" rel="stylesheet">
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    <link href="/Team:DTU-Denmark/font-awesome.css?action=raw&ctype=text/css" rel="stylesheet">
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    <script type="text/javascript" src="/Team:DTU-Denmark/jquery.js?action=raw&ctype=text/javascript"></script>
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    <script type="text/javascript" src="/Team:DTU-Denmark/bootstrap.js?action=raw&ctype=text/javascript"></script>
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</head>
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<body>
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<div class="container">
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<div class="row clearfix">
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<div class="col-md-12 column">
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<div class="page-header">
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<h1>Technical University of Denmark
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<!--small>Team Name</small-->
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</h1>
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</div>
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</div>
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    <div class="col-md-2">
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        <div class="sidebar-nav">
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<nav class="navbar navbar-default" role="navigation">
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<div class="collapse navbar-collapse" id="bs-example-navbar-collapse-1">
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<ul class="nav navbar-nav">
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<li class="dropdown active">
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<a href="/Team:DTU-Denmark"
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  >Home
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Team"
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  >Team
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                                          </a></li>
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<li class="dropdown">
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<a href=""
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  aria-expanded="false">Project
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                                          <span class="caret"></span></a><ul class="dropdown-menu" role="menu">
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Description"
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  >Description
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Experiments"
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  >Experiments & Protocols
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Results"
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  >Results
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Design"
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  >Design
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                                          </a></li></ul></li>
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<li class="dropdown">
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  aria-expanded="false">Parts
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                                          <span class="caret"></span></a><ul class="dropdown-menu" role="menu">
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Parts"
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  >Team Parts
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Basic_Part"
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  >Basic Parts
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Composite_Part"
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  >Composite Parts
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Part_Collection"
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  >Part Collection
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                                          </a></li></ul></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Notebook"
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  >Notebook
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Attributions"
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  >Attributions
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Collaborations"
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  >Collaborations
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Practices"
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  >Human Practices
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Safety"
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  >Safety
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Modeling"
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  >Modeling
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Measurement"
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  >Measurement
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Software"
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  >Software
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                                          </a></li>
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<li class="dropdown">
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<a href="/Team:DTU-Denmark/Entrepreneurship"
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  >Entrepreneurship
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                                          </a></li>
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</ul>
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</div>
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</nav>
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    <h2>
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        Project description
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    </h2>
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    <p>Nonribosomal peptides, polyketides and hybrids thereof are secondary metabolites that are biosynthesized by condensation of amino and/or carboxylic acids. These metabolites have a wide variety of important biological activities that include antibacterial, anticancer and immunosuppressing activities.</p>
  
 
<p>New ways to rationally design such products and creation of libraries that can be tested for desired activities can lead to new medicinally and industrially important products.</p>
 
<p>New ways to rationally design such products and creation of libraries that can be tested for desired activities can lead to new medicinally and industrially important products.</p>
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<p>Nonribosomal peptide synthetases(nrps) and polyketide synthases(pks) consist of many modules that incorporate one amino or carboxylic acid unto a growing chain. These modules can be rearranged and their specificity can be altered in order to make new products. The aim of our project is to design modules that can be combined in order to create nrps/pks hybrids as well as an easy way to create libraries of similar compounds with altered side chains based on an existing scaffold.</p>
 
<p>Nonribosomal peptide synthetases(nrps) and polyketide synthases(pks) consist of many modules that incorporate one amino or carboxylic acid unto a growing chain. These modules can be rearranged and their specificity can be altered in order to make new products. The aim of our project is to design modules that can be combined in order to create nrps/pks hybrids as well as an easy way to create libraries of similar compounds with altered side chains based on an existing scaffold.</p>
  
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<!--h2> Welcome to iGEM 2015! </h2>
 
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<p>Your team has been approved and you are ready to start the iGEM season! </p>
 
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<h4>Before you start: </h4>
 
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<p> Please read the following pages:</p>
 
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<ul>
 
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<li>  <a href="https://2015.igem.org/Requirements">Requirements page </a> </li>
 
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<li> <a href="https://2015.igem.org/Wiki_How-To">Wiki Requirements page</a></li>
 
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<h4> Styling your wiki </h4>
 
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<p>You may style this page as you like or you can simply leave the style as it is. You can easily keep the styling and edit the content of these default wiki pages with your project information and completely fulfill the requirement to document your project.</p>
 
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<p>While you may not win Best Wiki with this styling, your team is still eligible for all other awards. This default wiki meets the requirements, it improves navigability and ease of use for visitors, and you should not feel it is necessary to style beyond what has been provided.</p>
 
 
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<h4> Editing your wiki </h4>
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<p>On this page you can document your project, introduce your team members, document your progress and share your iGEM experience with the rest of the world! </p>  
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<p> <a href="https://2015.igem.org/wiki/index.php?title=Team:DTU-Denmark&action=edit"> Click here to edit this page! </a></p>
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<p>See tips on how to edit your wiki on the <a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation</a> page.</p>
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<h4>Templates </h4>
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<p> This year we have created templates for teams to use freely. More information on how to use and edit the templates can be found on the
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<a href="https://2015.igem.org/TemplatesforTeams_Code_Documentation">Template Documentation </a> page.</p>
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<h4>Tips</h4>
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<p>This wiki will be your team’s first interaction with the rest of the world, so here are a few tips to help you get started: </p>
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<ul>
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<li>State your accomplishments! Tell people what you have achieved from the start. </li>
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<li>Be clear about what you are doing and how you plan to do this.</li>
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<li>You have a global audience! Consider the different backgrounds that your users come from.</li>
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<li>Make sure information is easy to find; nothing should be more than 3 clicks away.  </li>
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<li>Avoid using very small fonts and low contrast colors; information should be easy to read.  </li>
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<li>Start documenting your project as early as possible; don’t leave anything to the last minute before the Wiki Freeze. For a complete list of deadlines visit the <a href="https://2015.igem.org/Calendar_of_Events">iGEM 2015 calendar</a> </li>
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<li>Have lots of fun! </li>
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<h4>Inspiration</h4>
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<p> You can also view other team wikis for inspiration! Here are some examples:</p>
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<ul>
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<li> <a href="https://2014.igem.org/Team:SDU-Denmark/"> 2014 SDU Denmark </a> </li>
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<li> <a href="https://2014.igem.org/Team:Aalto-Helsinki">2014 Aalto-Helsinki</a> </li>
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<li> <a href="https://2014.igem.org/Team:LMU-Munich">2014 LMU-Munich</a> </li>
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<li> <a href="https://2014.igem.org/Team:Michigan"> 2014 Michigan</a></li>
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<li> <a href="https://2014.igem.org/Team:ITESM-Guadalajara">2014 ITESM-Guadalajara </a></li>
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<li> <a href="https://2014.igem.org/Team:SCU-China"> 2014 SCU-China </a></li>
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</ul>
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<h4> Uploading pictures and files </h4>
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<p> You can upload your pictures and files to the iGEM 2015 server. Remember to keep all your pictures and files within your team's namespace or at least include your team's name in the file name. <br />
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When you upload, set the "Destination Filename" to <code>Team:YourOfficialTeamName/NameOfFile.jpg</code>. (If you don't do this, someone else might upload a different file with the same "Destination Filename", and your file would be erased!)</p>
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<a href="https://2015.igem.org/Special:Upload">CLICK HERE TO UPLOAD FILES</a>
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Revision as of 12:13, 7 August 2015

Technical University of Denmark

Project description

Nonribosomal peptides, polyketides and hybrids thereof are secondary metabolites that are biosynthesized by condensation of amino and/or carboxylic acids. These metabolites have a wide variety of important biological activities that include antibacterial, anticancer and immunosuppressing activities.

New ways to rationally design such products and creation of libraries that can be tested for desired activities can lead to new medicinally and industrially important products.

Nonribosomal peptide synthetases(nrps) and polyketide synthases(pks) consist of many modules that incorporate one amino or carboxylic acid unto a growing chain. These modules can be rearranged and their specificity can be altered in order to make new products. The aim of our project is to design modules that can be combined in order to create nrps/pks hybrids as well as an easy way to create libraries of similar compounds with altered side chains based on an existing scaffold.