Difference between revisions of "Team:Georgia State"
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<h3 class="h4" style="text-align: left;color: white;">Our Project</h3> | <h3 class="h4" style="text-align: left;color: white;">Our Project</h3> | ||
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− | <p class="lead" style="color: white;" > | + | <p class="lead" style="color: white;" ><a class="tipped" data-title="Abstract" data-tipper-options='{"direction":"top"}'><b>Protein Products from Plants and Pichia: Novel Manufacturing of Analgesics and Cannabinoids</b></a> Cannabinoids and opiates are widely used classes of pharmaceuticals; unfortunately, these drugs have strong psychoactive effects or can be addictive. Our project consists of two ideas, both revolving around utilizing bioengineered microorganisms to create non-psychoactive cannabinoids and non-addictive analgesics. To achieve this we developed two projects: (1) Manufacturing a protein expression system to produce CBDA synthase in tobacco plants using agrobacterium, (2) Engineering the pGAPα vector system to express the mambalgin in Pichia Pastoris as a continuation of the 2014 GSU iGEM project. Simultaneously, we developed a proof of concept using horseradish peroxidase. By the end of this project we hope to have produced a synthetic biological system to manufacture pharmaceutical alternatives for patients that suffer from diseases such as epilepsy, cancer, or chronic severe pain.</p> |
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Revision as of 18:02, 27 August 2015
Protein Products Pichia Plants
Our Project
Protein Products from Plants and Pichia: Novel Manufacturing of Analgesics and Cannabinoids Cannabinoids and opiates are widely used classes of pharmaceuticals; unfortunately, these drugs have strong psychoactive effects or can be addictive. Our project consists of two ideas, both revolving around utilizing bioengineered microorganisms to create non-psychoactive cannabinoids and non-addictive analgesics. To achieve this we developed two projects: (1) Manufacturing a protein expression system to produce CBDA synthase in tobacco plants using agrobacterium, (2) Engineering the pGAPα vector system to express the mambalgin in Pichia Pastoris as a continuation of the 2014 GSU iGEM project. Simultaneously, we developed a proof of concept using horseradish peroxidase. By the end of this project we hope to have produced a synthetic biological system to manufacture pharmaceutical alternatives for patients that suffer from diseases such as epilepsy, cancer, or chronic severe pain.
Sponsor
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