|
|
| Line 8: |
Line 8: |
| | <title>Team: Technion 2015</title> | | <title>Team: Technion 2015</title> |
| | </head> | | </head> |
| | + | <style> |
| | + | #pic_top{position: absolute; |
| | + | left: 200px; |
| | + | } |
| | + | |
| | + | .content{width:900px; |
| | + | height: 900px; |
| | + | position: absolute; |
| | + | left: 200px; |
| | + | top: 280px; |
| | + | background-color: white;} |
| | + | </style> |
| | <body> | | <body> |
| | | | |
| | <header> | | <header> |
| − |
| + | <div id="pic_top"> |
| − | <img src="https://static.igem.org/mediawiki/2015/e/e5/Technion_Israel_2015_Collaboration.jpg" alt="Collaboration_Photo" />
| + | <img style="border-top: 5px solid black; border-bottom: 5px solid black" src="https://static.igem.org/mediawiki/2015/e/e5/Technion_Israel_2015_Collaboration.jpg" alt="Collaboration_photo" width="900px" height="200px"> |
| − | | + | |
| − | <div class="main_menu"> | + | |
| − | <nav>
| + | |
| − | <a href="#">
| + | |
| − | <button class="button_main1"> | + | |
| − | <span class="btn-text">Project</span>
| + | |
| − | <span class="btn-bg"></span>
| + | |
| − | </button>
| + | |
| − | </a>
| + | |
| − | <a href="https://2015.igem.org/Team:Technion_Israel/Lab_Notebook">
| + | |
| − | <button class="button_main2">
| + | |
| − | <span class="btn-text">Lab Notebook</span>
| + | |
| − | <span class="btn-bg"></span>
| + | |
| − | </button>
| + | |
| − | </a>
| + | |
| − | <a href="#">
| + | |
| − | <button class="button_main3">
| + | |
| − | <span class="btn-text">Judging Criteria</span>
| + | |
| − | <span class="btn-bg"></span>
| + | |
| − | </button>
| + | |
| − | </a>
| + | |
| − | <a href="#">
| + | |
| − | <button class="button_main4">
| + | |
| − | <span class="btn-text">Human Practices</span>
| + | |
| − | <span class="btn-bg"></span>
| + | |
| − | </button>
| + | |
| − | </a>
| + | |
| − | <a href="#">
| + | |
| − | <button class="button_main5">
| + | |
| − | <span class="btn-text">Team</span>
| + | |
| − | <span class="btn-bg"></span>
| + | |
| − | </button>
| + | |
| − | </a>
| + | |
| − | </nav>
| + | |
| | </div> | | </div> |
| − | </header>
| |
| | | | |
| | <!---------------------------------------dropdown menu-----------------------------------> | | <!---------------------------------------dropdown menu-----------------------------------> |
| Line 111: |
Line 88: |
| | | | |
| | <div class="content"> | | <div class="content"> |
| − | <h1 class="abstract_title">Hello! Welcome to our temporary wiki page!</h1> | + | |
| − | <div class="abstract">
| + | |
| − | <b>Our team is developing a treatment for male pattern baldness.</b>
| + | |
| − | <p>
| + | |
| − | Hair loss affects roughly 61 million people in the United States. More than 95% of hair thinning in men is attributed to male pattern baldness, or androgenetic alopecia. The hair loss product market is a multi-billion dollar market: in the United States alone, this market’s annual revenue is 7 billion dollars, with 3.5% annual growth rate from 2007 to 2012, yet a sufficient solution has yet to be made available.
| + | |
| − | The trigger for androgenetic alopecia is believed to be dihydrotestosterone (DHT), a derivative of testosterone.
| + | |
| − | This summer, we are engineering Bacillus Subtilis, a model organism for a bacterium found naturally on the scalp, to secrete 3α-hydroxysteroid dehydrogenase (3-α-HSD). This enzyme reduces DHT to a non-steroidically active compound, using NADPH and NADH as cofactors.
| + | |
| − | </p>
| + | |
| − | <p>
| + | |
| − | Our project consists of 3 main parts: 3-α-HSD secretion by the bacterium, engineered bacterium for NADPH overproduction, and a comb as a tool to create a user-friendly experience.
| + | |
| − | By synchronizing these parts, we hope to be able to show convincing evidence of DHT breakdown, providing a promising platform for treatment of male pattern baldness!
| + | |
| − | </p>
| + | |
| − | </div>
| + | |
| | </div> | | </div> |
| | | | |
