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Revision as of 05:08, 4 September 2015
Platform for Electronmagnetic Control
HOW DOES IT WORK?
This summer we are trying to design a platform for remote regular of gene expression by electromagnetic signal.
STEP 1
The platform is mainly constructed by magnetic receiver and regulator.
STEP 2
Induced by electromagnetic fidle, magnetic receiver would be heated.
STEP 3
In response to change in temprature, thermosensitive regulator would activate GFP expression.
Magnetic Receiver
For magnetic receiver, we choose ferritin, the iron-storage protein in organisms, which could synthesis terric***core in its hollow protein shell. When exposed to electromagnetic field, the ferritin oxihydroxide core would be heated.
More details
Thermosensitive Regulator
For thermosensitive regulator, we choose RNA thermosensitive and constructed a thermosensitive T7 RNA polymerase. RNA thermometer is a structured RNA which could expose RBS only when heated. The thermosensitive T7 RNA polymerase is a normal T7 RNA polymerase at the selected locus of which was inserted by a temprature-sensitive intein, which could self-splice at specific temperature.
More detailsFollow us on facebook @IGEM_OUC
Mailto: oucigem@163.com
